The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Do three-spined sticklebacks avoid consuming copepods, the first intermediate host of Schistocephalus solidus ? — an experimental analysis of behavioural resistance [PDF]
Many parasites that use intermediate hosts are transmitted to the next host through predation. If the next host's fitness is strongly reduced by the parasite, it is under selection either to recognize and avoid infected intermediate hosts or to exclude ...
Milinski, M., Wedekind, C.
core
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Simulation based sequential Monte Carlo methods for discretely observed Markov processes [PDF]
Parameter estimation for discretely observed Markov processes is a challenging problem. However, simulation of Markov processes is straightforward using the Gillespie algorithm.
Neal, Peter
core
The Role of Behavioral Dynamics in Determining the Patch Distributions of Interacting Species [PDF]
The effect of the behavioral dynamics of movement on the population dynamics of interacting species in multipatch systems is studied. The behavioral dynamics of habitat choice used in a range of previous models are reviewed.
Abrams, Peter A. +2 more
core +2 more sources
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Intraguild Prey Served as Alternative Prey for Intraguild Predators in a Reciprocal Predator Guild between Neoseiulus barkeri and Scolothrips takahashii. [PDF]
Liu M +7 more
europepmc +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Larval fish and aquatic macroinvertebrates are believed to be at greater predation risk by visual riverine predators during periods of higher lunar illumination.
Joseph J. Riedy +2 more
doaj +1 more source
Predation of boreal owl nests by pine martens in the boreal forest does not vary as predicted by the alternative prey hypothesis. [PDF]
Sonerud GA.
europepmc +1 more source

