Results 111 to 120 of about 2,998,707 (241)

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

PREDATOR-PREY SYSTEMS IN PEST MANAGEMENT [PDF]

open access: yes
The use of chemical pesticides frequently causes minor pests to become serious problems by disturbing the natural controls that keep them in check. As a result, it is possible to suffer heavier crop losses after pesticides are introduced than before ...
Harper, Carolyn R.
core  

The resilience of weed seedbank regulation by carabid beetles, at continental scales, to alternative prey. [PDF]

open access: yesSci Rep, 2020
Carbonne B   +11 more
europepmc   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Prey-specific impact of cold pre-exposure

open access: yes, 2018
Number of prey killed and consumed, and number of eggs laid by female Gaeolaelaps aculeifer when feeding on Folsomia candida or Protaphorura fimata at 10 or 20 degrees Celsius after predator and/or prey have been pre-exposed to either ...
Martin Holmstrup (761777)   +9 more
core   +1 more source

Vulnerability of the mosquito larvae to the guppies (Poecilia reticulata) in the presence of alternative preys [PDF]

open access: yesJournal of Vector Borne Diseases, 2008
Background & objectives: The predatory potential of the larvivorous fishes can be affected by the presence of alternative preys. In the present study the predation pattern of the sewage dwelling Poecilia reticulata (Peters 1872) on the larvae of Culex ...
Barnali Manna   +2 more
doaj  

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

open access: yesFEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

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