Results 131 to 140 of about 1,434,923 (313)

Effects of NMR spectral resolution on protein structure calculation

, 2013
Adequate digital resolution and signal sensitivity are two critical factors for protein structure determinations by solution NMR spectroscopy. The prime objective for obtaining high digital resolution is to resolve peak overlap, especially in NOESY ...
Victor Jaravine, Peter Güntert (433824), Guntert, P., Tikole, S., Jaravine, Victor, Victor Jaravine (433822), Orekhov, Vladislav,, Orekhov, Vladislav Yu., Jaravine, Victor,, Vladislav Yu. Orekhov (433823), Suhas Tikole (433821), Tikol, Suhas, Suhas Tikole, Vladislav Yu Orekhov, Peter Güntert, Güntert, Peter   +15 more
core   +1 more source

The House Cricket (Acheta domesticus Linnaeus) in Food Industry: Farming, Technological Challenges, and Sustainability Considerations

Applied Sciences
The growing global demand for alternative, sustainable protein sources has increased interest in edible insects, of which the domestic cricket (Acheta domesticus Linnaeus) is one of the most studied and exploited species.
Viktória Ildikó Farkas, Mónika Máté, Krisztina Takács, Anna Jánosi   +3 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

InsectFish—The Use of Insect Meal in the Fish Sector in Creating Farm-to-Fork Value: Chemical and Quality Characteristics of Sparus aurata Fillets Fed Hermetia illucens Larvae-Based Feed

Foods
The aquaculture sector has seen significant growth recently but also faces sustainability challenges due to the use of fish meal and fish oil. This project explored the potential of using partially defatted Hermetia illucens (black soldier fly) larvae ...
Emma Copelotti, Giovanni Sogari, Giulia Andreani, Baldassare Fronte, Roberta Moruzzo, Chiara Sangiacomo, Asia Zanzot, Andrea Serra, Giuliana Parisi, Isabella Tucciarone, Liudmyla Fihurska, Manus Carey, Katrina Campbell, Simone Mancini   +13 more
doaj   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Valorization of Spent Coffee Grounds as a Functional Protein Ingredient for Sustainable Aquafeed Production

Applied Sciences
Spent coffee grounds (SCGs) represent a globally abundant agro-industrial byproduct with underexploited potential in circular bioeconomy applications.
Anca Becze, Dorina Simedru, Lucian Dordai, Adrian Vasile Timar, Paul Uiuiu   +4 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Industry 4.0 technologies for cultivated meat manufacturing

Food Bioengineering
Industry 4.0 integrates the physical, digital, and biological realms by applying digital automation in systems, processes, and manufacturing facilities.
Sishir K. Kamalapuram, Deepak Choudhury
doaj   +1 more source

A new and sustainable alternative food product: willingness to pay for cultured beef

Frontiers in Sustainable Food Systems
This study aimed to identify consumers in Türkiye's attitudes toward consuming cultured beef, a new and sustainable food product, their willingness to pay, and the factors influencing these consumption.
Gokhan Cinar, Sidika Bozkiran Yilmaz
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source