Results 141 to 150 of about 1,434,923 (313)

Investigating Cancer-related Proteins Specific Domain Interactions and Differential Protein Interactions Caused by Alternative Splicing

, 2012
[[abstract]]A strategy to gain a better understanding of disease proteins is to consider the interactions of these proteins by making use of the protein-protein interaction (PPI) data. It is known that proteins are composed of multiple functional domains.
吳家樂;Ng, Ka-Lok;蔡進發;Jeffrey, J.P.Tsai
core  

Alternative splicing of pre-mRNA in cancer: focus on G protein-coupled peptide hormone receptors

, 2009
Through alternative splicing, multiple different transcripts can be generated from a single gene. Alternative splicing represents an important molecular mechanism of gene regulation in physiological processes such as developmental programming as well as ...
Miller, Laurence J, Körner, Meike
core   +1 more source

Structural equation model of sensory preferences, acceptance, and purchase intentions of a novel food product and their relationship to emotional responses: the case of an instant congee product mixed with cricket protein powder

Cogent Business & Management
Sensory perceptions significantly influence consumer acceptance of innovative food products, including alternative protein sources like house cricket powder.
Peerapong Wongthahan, Amporn Sae-Eaw, Apirachai Wongsriworapon, Phurit Ngoenchai, Sarawut Chandeewanta, Lakkana Hengboriboon   +5 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Biochemical and Antioxidant Characterization of Pigment-Deficient Chlorella vulgaris Flours and the Impact of Fermentation: Comparative Insights from Green, Honey, and White Variants

Foods
This study investigated the biochemical composition and antioxidant potential of flours from pigment-deficient Chlorella vulgaris variants (honey and white) and wild-type (green) and the impact of lactic acid bacteria–yeast co-culture fermentation.
Nafiou Arouna, Elena Tomassi, Július Árvay, Manuel Venturi, Viola Galli, Laura Pucci   +5 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

PRODUCTION AND PROFITABILITY RESPONSES TO ALTERNATIVE PROTEIN SOURCES IN BROILER RATIONS

Profitability of using peanut meal as an alternative protein source in broiler production was investigated through the development of a two-stage mathematical program that optimizes broiler production.
Houston, Jack E., Pesti, Gene M., Costa, Ecio de Farias, Miller, Bill R.   +3 more
core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

PRODUCTION AND PROFITABILITY RESPONSES TO ALTERNATIVE PROTEIN SOURCES AND LEVELS IN BROILER RATIONS

Profitability of using alternative protein sources in broiler feed is investigated through the development of a two-stage mathematical program that optimizes broiler production. A case study of peanut meal vs. soybean meal is examined.
Houston, Jack E., Pesti, Gene M., Costa, Ecio de Farias, Miller, Bill R.   +3 more
core