Results 81 to 90 of about 1,434,923 (313)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Development and Characterization of Pasta Enriched with Giant Mealworm (Zophobas morio) Powder: An Innovative Nutritional Alternative

Insects
The growing global population has intensified the search for sustainable and nutritious food sources. This study evaluated the effects of incorporating giant mealworm (Zophobas morio) flour at levels of 0%, 7.5%, 15%, and 17.5% on the nutritional ...
Daniel da Silva Marte, Janevane da Silva Castro, Luiz Alves Bitu, Carlos Alberto Nascimento Souto, Adriano Lincoln Albuquerque Mattos, Rafael Audino Zambelli, Elisabeth Mary Cunha da Silva   +6 more
doaj   +1 more source

Alternate Proteins- An Alternate Method: sources of Alternate Proteins, Novel Methods of Extraction Proteins, The Public Attitude Towards Alternate Proteins - A Review

International Journal for Research in Applied Science and Engineering Technology
This study underscores the critical significance of alternative proteins, highlighting their pivotal role in enhancing human nutrition, fostering environmental sustainability, and strengthening food systems to ensure long-term resilience. As global consumption of meat and animal-based products continues to rise, it is contributing to profound ...
openaire   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Future Directions for Sustainable Poultry Feeding and Product Quality: Alternatives from Insects, Algae and Agro-Industrial Fermented By-Products

Agriculture
Due to global increases in poultry meat and egg production, consumers request sustainable agricultural practices, requiring alternative solutions for future feeding. Global egg production increased by over 41% between 2000 and 2020, from 51 to 87 million
Petru Alexandru Vlaicu, Raluca Paula Turcu, Mihaela Dumitru, Arabela Elena Untea, Alexandra Gabriela Oancea   +4 more
doaj   +1 more source

Black Soldier Fly (Hermetia Illucens) as Dietary Source for Laying Quails: Live Performance, and Egg Physico-Chemical Quality, Sensory Profile and Storage Stability

Animals, 2019
Insects are promising candidates as alternative sustainable sources of protein for poultry species. The present research studied the effect of a dietary inclusion of a defatted black soldier fly (BSF) larvae meal as an alternative protein source in the ...
Antonella Dalle Zotte, Yazavinder Singh, Joris Michiels, Marco Cullere   +3 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Large-scale identification and characterization of alternative splicing variants of human gene transcripts using 56 419 completely sequenced and manually annotated full-length cDNAs

, 2006
We report the first genome-wide identification and characterization of alternative splicing in human gene transcripts based on analysis of the full-length cDNAs.
Go, M., Nakao, M., Thierry-Mieg, J., Imanishi, T., Otsuki, T., Isogai, T., Takeda, J-I, Hata, H., Koyanagi, K.O., Gojobori, T., Suzuki, Y., Nomura, N., Yura, K., Shionyu, M., Jin, L., Motono, C., Kuryshev, V., Barrero, R.A., Wiemann, S., Nagai, K., Thierry-Mieg, D., Sugano, S.   +21 more
core  

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Nutritional evaluation of cuticle-intact and cuticle-removed silkworm (Bombyx mori) pupae meal in poultry diets: effects on production performance and fatty acid profiles of meat and eggs

Frontiers in Animal Science
IntroductionSilkworm (Bombyx mori) pupae meal (SWPM), a by-product of sericulture, is rich in high-quality protein (45–60%) and n-3 polyunsaturated fatty acids (PUFA). This study evaluated the effects of graded inclusion levels of cuticle-intact (SWPM-CI)
Vasanthakumar Periyannan, Kumaravel Varadharajan, Thirupathaiah Yeruva, Ravindra Aurade, Deepa P, Manthira Moorthy Shanmugam, Rajeswari Palani   +6 more
doaj   +1 more source