Results 161 to 170 of about 5,342,585 (286)

Mapping subcellular localizations of unannotated microproteins and alternative proteins with MicroID. [PDF]

open access: yesMol Cell, 2022
Na Z   +11 more
europepmc   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

From Curiosity to Consumption: Consumer Attitudes Toward Alternative Proteins in Northwestern Italy. [PDF]

open access: yesFoods
Garcia-Vozmediano A   +11 more
europepmc   +1 more source

Green, blue and red Exploring alternative proteins and novel foods

open access: yes, 2021
Kristianstad University.   +1 more
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Memorandum / Arbeitsgruppe Alternative Wirtschaftpolitik

open access: yes
MEMORANDUM / ARBEITSGRUPPE ALTERNATIVE WIRTSCHAFTPOLITIK Memorandum / Arbeitsgruppe Alternative Wirtschaftpolitik Memorandum, Alternativen der Wirtschaftspolitik / Arbeitsgruppe "Alternative ...
Arbeitsgruppe Alternative Wirtschaftspolitik
core   +1 more source

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