Results 121 to 130 of about 1,152,813 (297)
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Contact Leukoderma Induced by Latex Condom: A Case Report
Contact leukoderma occurs when certain chemicals are repeatedly exposed to the skin usually producing a hypopigmented skin condition without inflammation.
Somanaboina Padmakar +2 more
doaj +1 more source
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
MATRIX VALUATION PSEUDO RING (MVPR) AND AN EXTENSION THEOREM OF MATRIX VALUATION [PDF]
Let R be a ring and V be a matrix valuation on R. It is shown that, there exists a correspondence between matrix valuations on R and some special subsets ?(MVPR) of the set of all square matrices over R, analogous to the correspondence between invariant ...
doaj
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +2 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Holographic study on Einstein ring for a charged black hole in conformal gravity
Under the help of AdS/CFT correspondence, the Einstein ring of a charged black hole in conformal gravity has been studied. As an alternative to standard Einstein’s theory, the conformal gravity is both renormalizable and unitary.
Xin-Yun Hu +3 more
doaj +1 more source

