Results 211 to 220 of about 336,398 (336)

Engineered Fusion Enzyme‐Mediated Non‐Consecutive Cyclization‐Glycosylation Enables Heterologous Synthesis of Antifungal Enfumafungin

Advanced Science, EarlyView.
The artificial biosynthetic pathway potentially involved in biosynthesis of enfumafungin is first reconstructed in an optimized Aspergillus oryzae chassis with the increased site‐specific integration efficiency and shortened time for marker recycling, which requires an artificial fusion enzyme EfuA(TC)FsoA(GT).
Yaohui Gao, Jianming Lv, Yue Zhong, Zhiqin Cao, Rui Luo, Yue Qi, Gaoqian Wang, Shaoyang Li, Guodong Chen, Dan Hu, Hao Gao, Xinsheng Yao   +11 more
wiley   +1 more source

Angel wing: a class of alternative splicing regulators in animals. [PDF]

Nucleic Acids Res
Zhang T, Li K, Xiao Y, Tan X, Tan X, Cui M, Rong YS.   +6 more
europepmc   +1 more source

Human fibronectin: cell specific alternative mRNA splicing generates polypeptide chains dfffering in the number of internal repeats

, 1984
Alberto R. Kornblihtt, Karen Vibe‐Pedersen, Francisco E. Baralle   +2 more
openalex   +2 more sources

H3K27ac Is Essential for Human Naive Pluripotency Modulated by m6A‐Driven EP300 Expression

Advanced Science, EarlyView.
An et al. reveal H3K27ac elevation is essential for establishing and maintaining human naive pluripotency; its inhibition disrupts this state while enhancement promotes it. METTL3‐mediated m6A modification indirectly controls H3K27ac by suppressing EP300 expression. Reduced EP300 lowers H3K27ac, impeding naive pluripotency.
Chenrui An, Ke Zhong, Xiangjin Kang, Yingying Zhang, Yudan Shang, Hao Liu, Yushan Ji, Jinbei Zeng, Jiajin Lin, Long Jin, Zelong Lin, Yang Yu, Xuetao Shi, Yong Fan   +13 more
wiley   +1 more source

Aberrant alternative splicing in alcoholic hepatitis: regulatory roles of RBPs and sQTLs. [PDF]

BMC Gastroenterol
Zhao J, Cheng J, Liang S, Guo W, Zhao B, Zhang H, Mei X, Zhang N, Sheng M.   +8 more
europepmc   +1 more source

Human endothelial cells synthesize, process, and secrete fibronectin molecules bearing an alternatively spliced type III homology (ED1) [PDF]

, 1990
JH Peters, LA Sporn, MH Ginsberg, DD Wagner   +3 more
openalex   +1 more source

Tumor Intrinsic METTL5 Modulates ATF4 Translation to Prevent T Cell‐Induced Ferroptosis in Ovarian Cancer

Advanced Science, EarlyView.
An integrative analysis combining in vitro genome‐wide immune screens, in vivo ICB screens, and clinical data mining identifies METTL5 as a key tumor‐intrinsic immune factor. Mechanistic studies further reveal the importance of the METTL5‐ATF4‐SLC7A11/SLC3A2‐ferroptosis axis in modulating antitumor immune responses. These findings highlight METTL5 as a
Jiakai Hou, Cheng‐Wei Ju, Nicholas A. Egan, Yanjun Wei, Yunfei Wang, Minghao Dang, Tianyi Zhou, Leilei Shi, Ningbo Zheng, Si Chen, Ashley M. Guerrero, Xiaofang Liang, Wanfu Wu, Areej Akhtar, Chitra Dhiman, Debanwita Roy Burman, Andro E. Gerges, Mason D. Flores, Han Li, Li‐Sheng Zhang, Marleen Kok, Xiaobo Mao, Linghua Wang, Qin Feng, Yiwen Chen, Sanghoon Lee, Daniel J. McGrail, Nidhi Sahni, Chuan He, Amir A. Jazaeri, Weiyi Peng   +30 more
wiley   +1 more source

ZC3H18 regulates alternative splicing and related genes in cervical cancer. [PDF]

Front Genet
Chen W, Liu C, Li S, Xie X, Hu D, Lin Y.
europepmc   +1 more source

Platelet-derived growth factor A chain: gene structure, chromosomal location, and basis for alternative mRNA splicing.

, 1988
David T. Bonthron, Cynthia C. Morton, Stuart H. Orkin, Teresa Collins   +3 more
openalex   +1 more source

Multiple isoforms of the mouse retinoic acid receptor alpha are generated by alternative splicing and differential induction by retinoic acid. [PDF]

, 1991
Pierre Leroy, A. Krust, Arthur Zelent, Cathy Mendelsohn, Jean‐Marie Garnier, Philippe Kastner, A. Dierich, Pierre Chambon   +7 more
openalex   +1 more source