Results 221 to 230 of about 336,398 (336)

IPGCA: A Comprehensive Single Cell Atlas of 1 074 127 Porcine Intestinal Cells Revealing Cellular Dynamics, Genetic Regulation, and Cross‐Species Conservation

Advanced Science, EarlyView.
A high resolution integrated cell atlas of the pig intestine provides insights into the genetic mechanisms of complex traits (Created in BioRender. Yu, P. (2025) https://BioRender.com/o14c563) Abstract The porcine intestinal tract is vital for nutrient absorption, immune regulation, and various physiological processes.
Pengfei Yu, Qinqin Xie, Xiaodian Cai, Zhanming Zhong, Ran Wei, He Han, Shuang Liu, Zhenyang Zhang, Lingyao Xu, Zitao Chen, Zhe Zhang, Qishan Wang, Yuchun Pan, Zhen Wang, Zhe Zhang   +14 more
wiley   +1 more source

Alternative Splicing Regulation in Metabolic Disorders. [PDF]

Obes Rev
Kaminska D.
europepmc   +1 more source

The rat alpha-tropomyosin gene generates a minimum of six different mRNAs coding for striated, smooth, and nonmuscle isoforms by alternative splicing.

, 1988
David F. Wieczorek, Christopher W. J. Smith, Bernardo Nadal‐Ginard   +2 more
openalex   +1 more source

Multiple Rh messenger RNA isoforms are produced by alternative splicing [PDF]

, 1992
Caroline Le Van Kim, Baya Chérif‐Zahar, V Raynal, Isabelle Mouro-Chanteloup, Marc Lopez, JP Cartron, Yves Colin   +6 more
openalex   +1 more source

Comparative Cochlear Transcriptomics in Echolocating Bats and Mouse Reveals Hras as Protector Against Noise‐Induced Hearing Loss

Advanced Science, EarlyView.
Comparative cochlear transcriptomics of noise‐exposed bats (Miniopterus fuliginosus) and mice reveals bat‐specific protection mechanisms for noise‐induced hearing loss (NIHL), identifying Hras as a key hub regulator. Functional studies in mice show hair‐cell‐specific Hras overexpression significantly reduced hair‐cell damage and NIHL by activating the ...
Peng Chen, Chenhao Che, Lingjie Wu, Changjie Sun, Dongming Xu, Qinyang Hua, Yunzhong Zhang, Yi‐Quan Tang, Peng Shi, Shan Sun   +9 more
wiley   +1 more source

Autism and mild epilepsy associated with a de novo missense pathogenic variant in the GTPase effector domain of DNM1

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView., 2023
Abstract Dynamin 1 is a GTPase protein involved in synaptic vesicle fission, which facilitates the exocytosis of neurotransmitters necessary for normal signaling. Pathogenic variants in the DNM1 gene are associated with intractable epilepsy, often manifested as infantile spasms at onset, developmental delay, and a movement disorder, and are located in ...
Davide Mei, Elena Parrini, Claudia Bianchini, Maria Luisa Ricci, Renzo Guerrini   +4 more
wiley   +1 more source

Alternative Splicing in Tumorigenesis and Cancer Therapy. [PDF]

Biomolecules
Chen H, Tang J, Xiang J.
europepmc   +1 more source

Coronavirus leader‐RNA‐primed transcription: An alternative mechanism to RNA splicing

, 1986
Michael M. C. Lai
openalex   +1 more source

Pre-pre-B acute lymphoblastic leukemia: high frequency of alternatively spliced ALL1-AF4 transcripts and absence of minimal residual disease during complete remission [PDF]

, 1994
JW Janssen, WD Ludwig, Arndt Borkhardt, U Spadinger, Harald Rieder, Christa Fonatsch, DK Hossfeld, Jochen Harbott, AS Schulz, Reinald Repp   +9 more
openalex   +1 more source

Stage‐Resolved Phosphoproteomic Landscape of Mouse Spermiogenesis Reveals Key Kinase Signaling in Sperm Morphogenesis

Advanced Science, EarlyView.
The quantitative proteomic and phosphoproteomic profiling reveals dynamic phosphorylation regulation of sperm morphogenesis. Kinase‐substrate phosphorylation network and phosphorylation module analysis, followed by in vivo knockdown and knockout analysis, identify TTBK2 and CSNK1G1 as key regulators of morphogenesis, including head, flagellar, and ...
Tianyu Zhu, Yan Zhu, Xinyi Jiang, Xiangzheng Zhang, Bing Wang, Yu Chen, Yichen Zhao, Yulian Wang, Qi Zhou, Zhongyan Han, Yaling Qi, Mengjiao Luo, Haixia Tu, Bingjie Hao, Mengmeng Gao, Jie Ren, Xin Zhou, Xingyu Zhang, Xu Chen, Haojie Li, Qian Huang, Chenghao Situ, Yueshuai Guo, Hui Zhu, Yan Li, Xuejiang Guo   +25 more
wiley   +1 more source