Results 251 to 260 of about 50,888 (294)

Risk assessment: alternatives to animal testing

1997
All new chemicals manufactured specifically for use in food are required to be evaluated for safety. Such chemicals which are intentionally incorporated into foods are additives, and this chapter focuses on their safety assessment. Each proposed food additive is subjected to various in vivo and in vitro assays, which may include tests for genotoxicity,
C. L. Broadhead, R. D. Combes, M. Balls
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Advancing alternative methods to reduce animal testing

Science
Emerging approaches show promise for regulatory ...
Chad P, Nelson, Paul, Brown, Suzanne, Fitzpatrick, Kevin A, Ford, Paul C, Howard, Tracy, MacGill, Edward E C, Margerrison, Jacqueline, O'Shaughnessy, Tucker A, Patterson, Rakesh, Raghuwanshi, Rodney, Rouse, Selen, Stromgren, Kyung E, Sung, Luis G, Valerio, Jeffrey L, Ward, Namandjé N, Bumpus   +15 more
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The Validation and Acceptance of Alternatives to Animal Testing

Toxicology in Vitro, 1999
Validation is the key to the regulatory status of alternative methods. A series of questions are put, to which answers are given, including the following: What is validation? What is meant by "relevance", "reliability" and "purpose"? Why and when is formal validation necessary? What comes before and after a formal validation study?
M, Balls, J H, Fentem
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Trend on alternative to animal testing

International Journal of Cosmetic Science, 2007
For the promotion of 3R's (Reduction, Refinement and Replacement) principles of animal tests, the EU and US established the European Center for the Validation of Alternative Methods (ECVAM) and the Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM), respectively.
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Search for alternatives to animal testing expands

JAMA: The Journal of the American Medical Association, 1981
The Johns Hopkins University, Baltimore, has become the third major research institution this year to agree to seek alternatives to the use of animals for testing the safety of commercial products, and this may be only the beginning. The university's School of Hygiene and Public Health is accepting a $1 million grant from the Cosmetic, Toiletry, and ...
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[Alternatives to animal testing].

Bulletin de l'Academie nationale de medecine, 2010
The use of alternative methods to animal testing are an integral part of the 3Rs concept (refine, reduce, replace) defined by Russel & Burch in 1959. These approaches include in silico methods (databases and computer models), in vitro physicochemical analysis, biological methods using bacteria or isolated cells, reconstructed enzyme systems, and ...
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Welcome Alternatives to Animal Testing

Genetic Engineering & Biotechnology News, 2021
Gary Michelson, Aysha Akhtar
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The Johns Hopkins Center for Alternatives to Animal Testing

Toxicological Sciences, 1984
The Center strives to develop new non-whole-animal test methodologies based on understanding mechanisms of toxicity of chemicals, consumer products, and drugs for the evaluation of safety. The Center will strive for scientific excellence, and to provide superior methods which will replace existing strategies.
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Alternatives to Animal Testing in the Safety Evaluation of Products

Alternatives to Laboratory Animals, 2002
The conventional method for assessing the safety of products, ranging from pharmaceuticals to agrochemicals, biocides and industrial and household chemicals — including cosmetics — involves determining their toxicological properties by using experimental animals.
Derek J, Knight, Damien, Breheny
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