Results 51 to 60 of about 6,346 (209)

Downregulation of EPAS1 and EGLN1 mRNA Expression Associated With High‐Altitude Adaptive Genetic Variants in Sherpa Highlanders

open access: yesAnnals of Human Genetics, EarlyView.
ABSTRACT Background and Aims Sherpa highlanders exhibit remarkable tolerance to hypoxia, most likely due to genetic adaptations shaped by natural selection at high altitude. This study examined the roles of endothelial PAS domain protein 1 (EPAS1) and egl‐9 family hypoxia‐inducible factor 1 (EGLN1) in the genetic mechanisms underlying this adaptation ...
Yunden Droma   +5 more
wiley   +1 more source

Tick‐Borne Encephalitis (TBE) Vaccine in the National Immunisation Programme—For Whom, When and Where?

open access: yesActa Paediatrica, EarlyView.
ABSTRACT The incidence of Tick‐borne encephalitis (TBE) cases has increased. The presumed location of transmission of Tick‐borne encephalitis virus (TBEV) has been expanding increasingly in the western parts of Europe during the past decade. There has also been an increased incidence of surveillance‐reported TBE cases in southern Sweden and southern ...
H. H. Askling, D. Zavadska
wiley   +1 more source

Obesity as a Conditioning Factor for High-Altitude Diseases

open access: yesObesity Facts, 2017
Obesity, a worldwide epidemic, has become a major health burden because it is usually accompanied by an increased risk for insulin resistance, diabetes, hypertension, cardiovascular diseases, and even some kinds of cancer.
Rocío San Martin   +3 more
doaj   +1 more source

Cellular Signalling Networks in High Altitude Pulmonary Hypertension: From Canonical Pathways to Emerging Targets

open access: yesCell Proliferation, EarlyView.
This review elucidates the intricate cellular signalling networks involved in high‐altitude pulmonary hypertension (HAPH), integrating canonical pathways like HIF, MAPK and BMP with emerging targets such as Wnt/β‐catenin, Notch, Hippo‐YAP and IL‐6. It highlights potential therapeutic strategies targeting these pathways to mitigate vascular remodelling ...
Sheng Ding   +8 more
wiley   +1 more source

Neuroimaging features of fatal high-altitude cerebral edema

open access: yesIndian Journal of Radiology and Imaging, 2018
Acute high-altitude cerebral edema can occur in an unacclimatised individual on exposure to high altitudes and sometimes it can be fatal. Here we have described the neuroimaging features of a patient who suffered from fatal high altitude cerebral edema ...
Gorky Medhi   +2 more
doaj   +1 more source

1166. Helianthus occidentalis Riddell

open access: yesCurtis's Botanical Magazine, EarlyView.
Summary Helianthus occidentalis Riddell (Compositae: Heliantheae: Helianthinae) is described and illustrated. The species' placement in the genus is commented on, as are the differences in infrageneric placement of the other species Heiser originally grouped H. occidentalis with.
Nicholas Hind, Christabel King
wiley   +1 more source

The caliph and the falcons: a ninth‐century history from Iceland to Iraq

open access: yesEarly Medieval Europe, EarlyView.
In the late ninth and early tenth centuries, an extraordinary number of falcons were given to the ʿAbbāsid caliphs in Baghdad, many of which were white. Gifts from competing dynasties in the northern provinces of the Caliphate, at least some of these birds were almost certainly gyrfalcons from near the Arctic Circle.
Caitlin Ellis, Sam Ottewill‐Soulsby
wiley   +1 more source

High-altitude headache and acute mountain sickness

open access: yesNeurología (English Edition), 2014
Introduction: Headache is the most common complication associated with exposure to high altitude, and can appear as an isolated high-altitude headache (HAH) or in conjunction with acute mountain sickness (AMS).
F.J. Carod-Artal
doaj   +1 more source

The (Im)possibilities of Repopulation: How Supply‐Side Factors Hinder the Revitalisation of Vacant Houses in Rural Mountain Regions

open access: yesThe Geographical Journal, EarlyView.
Short Abstract Industrialisation has reshaped European rural areas, leading to both depopulation and, in some cases, lifestyle‐driven repopulation. Our research highlights supply‐side barriers to Alpine repopulation by unpacking the impossibilities of vacant farmhouses revitalisation. Both land transfer traditions ingrained over generation (micro‐level
Bernhard Grüner, Elisabeth Gruber
wiley   +1 more source

Establishing reference intervals for 25 common biochemical analytes in Tibetans living at very high altitude

open access: yesOpen Medicine
High altitude poses extreme living environment for humans, impacting human physiology and leading to physiological adaptations, including higher hemoglobin levels in highlanders.
Ci Bai   +9 more
doaj   +1 more source

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