Results 31 to 40 of about 32,385 (167)
A Chemically Defined Four-Component Self-Adjuvanting Tn Vaccine Activating Mincle, FcγR, and CD206 for Enhanced Antitumor Immunity. [PDF]
Adv Sci (Weinh)A fully synthetic four‐component vaccine has been developed combining Tn antigen, vizantin (Mincle agonist), rhamnose (antibody recruitment), and mannose (CD206 targeting). By synergistically activating Mincle, FcγR, and CD206 pathways, it elicits strong IgG switching and cytotoxic T‐cells, significantly inhibiting tumors in mice.
Ming W +9 more
europepmc +2 more sources
Advanced Science, EarlyView.Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib +8 more
wiley +1 more source
Application of Dual Coagulant (Alum + Barley) in Removing Colour from Leachate
MATEC Web of Conferences, 2017 Coagulation/flocculation is one of the treatment method for highly polluted leachate. One of the main affecting factor for this process is the coagulant used. Coagulant is divided into natural and chemical coagulant.
Shaylinda Mohd Zin Nur +1 more
doaj +1 more source
Veterinary World, 2013 Aim: To compare the newly formulated enterotoxaemia vaccine having oil and alum adjuvants, with presently available toxoid and alum precipitated vaccines.
Ajay Kumar Rai +5 more
doaj +1 more source
Advanced Science, EarlyView.Sustained delivery of a shingles subunit vaccine from an injectable polymer–nanoparticle hydrogel enhanced the potency, durability, and breadth of immune responses in aged mice while minimizing inflammatory cytokine production and reactogenicity. This strategy decouples immunogenicity from reactogenicity and offers a promising approach to improve ...
Ye Eun Song +5 more
wiley +1 more source
Advanced Science, EarlyView.Antigenic peptides Aβ42 and E7 self‐assemble into nanofibrils; APTES and TEOS induce SiO2 NP formation on these fibrils to form SiO2@fibril nanovaccines, which activate BMDCs in vitro. In vivo, SiO2@Aβ42 fibril nanovaccines alleviate AD symptoms and clear Aβ42 plaques in APP/PS1 mice, and SiO2@E7 fibril nanovaccines inhibit tumor growth and promote ...
Xuecheng Yang +6 more
wiley +1 more source
Evaluation of a Novel Poultry Litter Amendment on Greenhouse Gas Emissions
Atmosphere, 2021 Gaseous emissions from poultry litter causes production problems for producers as well as the environment, by contributing to climate change and reducing air quality.
Kelsey Anderson +3 more
doaj +1 more source
Endothelial YAP Signaling Promotes Blood‐Spinal Cord Barrier Repair in Mice After Spinal Cord Injury
Advanced Science, EarlyView.Endothelial YAP is required for blood‐spinal cord barrier repair after spinal cord injury. YAP‐dependent vascular repair is associated with ANGPT1/PI3K/AKT signaling in vivo and may involve endothelial‐pericyte paracrine interactions. By supporting vascular remodeling, tight junction restoration, restored pericyte coverage, and astrocyte‐vascular ...
Jiawei Wang +14 more
wiley +1 more source
Formulation of oral mucoadhesive form of alum and its clinical assessment [PDF]
Journal of Kerman University of Medical Sciences, 2000 Alum had been used in traditional medicine for treatment of oral lesions in Iran.the main aim of this study was to find out a suitable formulation for the mucoadhesive fprm of alum.in this study some materials such as alum,carboxymethyl cellulose (CMC ...
A.A Moghadam nia +2 more
doaj
Short or Long Interval between Priming and Boosting: Does It Impact on the Vaccine Immunogenicity?
Vaccines, 2021 Characterizing the impact of the vaccination schedule on the induction of B and T cell immune responses is critical for improving vaccine immunogenicity.
Elena Pettini +4 more
doaj +1 more source