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Aluminum toxicity to the brain

Science of The Total Environment, 1988
The association between elevated brain aluminum levels and Alzheimer's disease (AD) is examined and critically reviewed. We found elevated aluminum levels in the brains of patients with AD (greater than 4 micrograms/g dry wt.) compared with normal subjects (approximately 1.5 micrograms/g dry wt.).
S S, Krishnan   +4 more
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Aspects of Aluminum Toxicity

Clinics in Laboratory Medicine, 1990
Aluminum is the most abundant metal in the earth's crust. The widespread occurrence of aluminum, both in the environment and in foodstuffs, makes it virtually impossible for man to avoid exposure to this metal ion. Attention was first drawn to the potential role of aluminum as a toxic metal over 50 years ago, but was dismissed as a toxic agent as ...
C D, Hewitt, J, Savory, M R, Wills
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Aluminum toxicity. Hematological effects

Toxicology Letters, 2000
Sequential effects of intoxication with aluminum hydroxide (Al) (80 mg/Kg body weight, i.p., three times a week), were studied on rats from weaning and up to 28 weeks. The study was carried out on hematological and iron metabolism-related parameters on peripheral blood, at the end of the 1st, 2nd, 3rd, 4th, 5th and 6th months of exposure.
S, Mahieu   +4 more
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Aluminum and toxicity

2023
Aluminum (Al) is the third most prevalent element on earth after oxygen and silicon. Al compounds are used in the production of many different products including pots, pans, paints, varnishes, lubricants, cosmetics, vaccinations, pharmaceuticals, and nano-carrier systems, in the field of veterinary medicine and industry.
GÖKMEN, Sedat, GÜL, Burcu
openaire   +1 more source

Axonal transport of cytoskeletal proteins in aluminum toxicity

Neurochemical Pathology, 1983
Aluminum administration in certain species results in the accumulation of neurofilament bundles within the neuronal perikaryon and the proximal neuronal processes. The study presented here was designed to investigate how aluminum exerts its effects on the neuronal cytoskeleton.
K S, Kosik   +3 more
openaire   +2 more sources

[Aluminum toxicity].

Klinische Wochenschrift, 1990
In view of the increasing pollution of our environment and forest decline, growing interest has been focused on aluminum toxicity. Aluminum is one of the most abundant metals and commonly present in tap water, beverages, food, cosmetics, and pharmaceutical preparations. Thus everybody is exposed to aluminum to a greater or lesser extent.
openaire   +1 more source

Aluminum Toxicity

Archives of Pediatrics & Adolescent Medicine, 1998
E, Gilbert-Barness   +3 more
openaire   +2 more sources

Aluminum toxicity and albumin.

ASAIO transactions, 1990
During a study of priming solutions for extracorporeal membrane oxygenation (ECMO) in the intensive care nursery, it was discovered that those solutions using certain brands of 25% albumin contained aluminum levels within the toxic range. When the brand was changed to a brand known to have a lower aluminum (Al) content, a marked drop in priming ...
A T, Kelly   +4 more
openaire   +1 more source

Aluminum Toxicity in Humans

1990
Systemically administered aluminum can cause severe toxicity primarily effecting the neurological, skeletal and hematopoietic systems. Humans have largely been protected from toxicity because of the insoluble nature of most aluminum compounds. However, when administered with citrate aluminum compounds can be solubilized, and absorption markedly ...
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Chronic aluminum toxicity: effects of aluminum on neurotransmitters

Neurobiology of Aging, 1986
Abstract Available data suggest that chronic neurotoxicity may be associated with repeated dietary exposure to extremely low concentrations of aluminum in susceptible populations. Adverse effects of aluminum on central neurotransmitter function have been demonstrated both in vivo and in vitro with several different aluminum salts.
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