Clade Dynamics and Persistence of ALV-J in Taiwan Poultry Populations
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Prolactin affects the disappearance of ALV-J viremia in vivo and inhibits viral infection
Veterinary Microbiology, 2021Based on the RNA-seq data of chicken spleen tissues infected with J subgroup avian leukosis virus (ALV-J), we found that prolactin (PRL) gene was one of differentially expressed gene. We measured ALV-J viremia and PRL levels in the plasma of two groups of ALV-J-infected adult chickens.
Min Feng, Hongmei Li, Xiquan Zhang
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Immunochromatographic test (ICT) for the detection of antibody against ALV-J
The Thai Journal of Veterinary Medicine, 2022ALV-J is an important pathogen in the poultry industry in China. In this study, we developed an immunochromatographic test (ICT) assay for the detection of antibody against of ALV-J to evaluate ALV-J infection. Gp85 protein of ALV-J was employed as a capture antigen.
Guihua Wang, Yanming Wang, Ziqiang Cheng
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Exosomes carring gag/env of ALV-J possess negative effect on immunocytes
Microbial Pathogenesis, 2017J subgroup avian leukosis virus (ALV-J) is an exogenous retrovirus of avian. A key feature of ALV-J infection is leading to severe immunosuppressive characteristic of diseases. Viral components of retrovirus were reported closely associated with immunosuppression, and several similarities between exosomes and retrovirus preparations have lead to the ...
Gen Li, Xiaomin Zhao, Guihua Wang
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An ALV-J isolate is responsible for spontaneous haemangiomas in layer chickens in China
Avian Pathology, 2011Subgroup J avian leukosis virus (ALV-J), first isolated in 1989, mainly induces tumours of myeloid leukosis (ML) in meat-type chickens. In 2006, ALV-J strain SCAU-HN06 was isolated from commercial layer hens with spontaneous haemangiomas in China. To confirm its role in the induction of haemangioma, we constructed a full-length copy of the proviral ...
He-nan, Zhang +8 more
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gp85 protein vaccine adjuvanted with silica nanoparticles against ALV-J in chickens
Vaccine, 2017This study focused on the effect of silica nanoparticles as adjuvant for vaccine applications comprised of gp85, a dominating structural protein of J Subgroup Avian Leukosis Virus (ALV-J), and which was evaluated by comparing with the responsiveness induced by that emulsified in Freund adjuvant.
Jia, Cheng +7 more
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Generierung ALV-J resistenter Hühner mittels Gen-Editierung
2021ALV-J is an oncogenic, immunosuppressive retrovirus which infects chickens. It causes myeloid leucosis and leads to reduced growth and laying performance. The virus is difficult to control due to a lack of adequate prevention measures, such as an effective vaccine.
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MiR-34b-5p Suppresses Melanoma Differentiation-Associated Gene 5 (MDA5) Signaling Pathway to Promote Avian Leukosis Virus Subgroup J (ALV-J)-Infected Cells Proliferaction and ALV-J Replication [PDF]
Frontiers in Cellular and Infection Microbiology, 2017 Avian leukosis virus subgroup J (ALV-J) is an oncogenic retrovirus that has a similar replication cycle to multiple viruses and therefore can be used as a model system for viral entry into host cells. However, there are few reports on the genes or microRNAs (miRNAs) that are responsible for the replication of ALV-J.
Min Feng +2 more
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Liposomes containing recombinant gp85 protein vaccine against ALV-J in chickens
Vaccine, 2014To study the potential of liposome vaccines in the clinical prevention of ALV-J, the effect of recombinant gp85 protein of subgroup J avian leukosis virus (ALV-J) entrapped by liposomes in chickens against ALV-J infection was investigated in this paper.
Limei, Zhang +9 more
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THY1 inhibits the replication of ALV - J by diverting chNHE1 for proteasomal degradation
International Journal of Biological MacromoleculesAvian leukosis virus subgroup J (ALV-J) induces myelocytoma and immunosuppression in infected chickens, thereby severely affecting the global poultry industry. Viruses generally utilize the host cellular machinery for their own replication. However, the interaction relationships between ALV-J and host proteins remain poorly understood.
Qinxi, Chen +10 more
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