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gp85 protein vaccine adjuvanted with silica nanoparticles against ALV-J in chickens
Vaccine, 2017This study focused on the effect of silica nanoparticles as adjuvant for vaccine applications comprised of gp85, a dominating structural protein of J Subgroup Avian Leukosis Virus (ALV-J), and which was evaluated by comparing with the responsiveness induced by that emulsified in Freund adjuvant.
Jia, Cheng +7 more
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Exosomes carring gag/env of ALV-J possess negative effect on immunocytes
Microbial Pathogenesis, 2017J subgroup avian leukosis virus (ALV-J) is an exogenous retrovirus of avian. A key feature of ALV-J infection is leading to severe immunosuppressive characteristic of diseases. Viral components of retrovirus were reported closely associated with immunosuppression, and several similarities between exosomes and retrovirus preparations have lead to the ...
Guihua, Wang +4 more
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Prolactin affects the disappearance of ALV-J viremia in vivo and inhibits viral infection
Veterinary Microbiology, 2021Based on the RNA-seq data of chicken spleen tissues infected with J subgroup avian leukosis virus (ALV-J), we found that prolactin (PRL) gene was one of differentially expressed gene. We measured ALV-J viremia and PRL levels in the plasma of two groups of ALV-J-infected adult chickens.
Guodong Mo +11 more
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An ALV-J isolate is responsible for spontaneous haemangiomas in layer chickens in China
Avian Pathology, 2011Subgroup J avian leukosis virus (ALV-J), first isolated in 1989, mainly induces tumours of myeloid leukosis (ML) in meat-type chickens. In 2006, ALV-J strain SCAU-HN06 was isolated from commercial layer hens with spontaneous haemangiomas in China. To confirm its role in the induction of haemangioma, we constructed a full-length copy of the proviral ...
He-nan, Zhang +8 more
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Chicken biliary exosomes enhance CD4+T proliferation and inhibit ALV-J replication in liver
Biochemistry and Cell Biology, 2014Exosomes, which are small membrane vesicles of endocytic origin, carry lipids, RNA/miRNAs, and proteins and have immune modulatory functions. In this study, we isolated exosomes from the bile of specific pathogen-free chickens, 42–43 days of age, by using an ultracentrifugation and filtration method.
Yue, Wang +5 more
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[The identification and sequence analysis of ALV-J isolated from layers].
Bing du xue bao = Chinese journal of virology, 2009Two Avian leukosis viruses of subgroup J (ALV-J) were isolated from layers by inoculating the sample into chicken embryo fibroblast (CEF) cells and by indirect fluorescent assay (IFA) with ALV-J specific monoclonal antibody JE-9. Sequence comparison indicated the gp85 identities were only in the ranges of 83.4%-87.3% compared with five international ...
Hui, Wang, Zhi-Zhong, Cui
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Identification of ALV-J associated acutely transforming virus Fu-J carrying complete v-fps oncogene
Virus Genes, 2016Transduction of oncogenes by ALVs and generation of acute transforming viruses is common in natural viral infections. In order to understand the molecular basis for the rapid oncogenicity of Fu-J, an acutely transforming avian leukosis virus isolated from fibrosarcomas in crossbreed broilers infected with subgroup J avian leukosis virus (ALV-J) in ...
Yixin, Wang +7 more
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Transboundary and Emerging Diseases, 2018
One avian leukosis virus subgroup J (ALV-J) strain was isolated from 67 commercial live poultry vaccines produced by various manufacturers during 2013-2016 in China. The complete genomes of the isolate were sequenced and it was found that the genes gag and pol of the strain were relatively conservative, while the gp85 gene of the strain GX14YYA1 had ...
P. Wang +5 more
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One avian leukosis virus subgroup J (ALV-J) strain was isolated from 67 commercial live poultry vaccines produced by various manufacturers during 2013-2016 in China. The complete genomes of the isolate were sequenced and it was found that the genes gag and pol of the strain were relatively conservative, while the gp85 gene of the strain GX14YYA1 had ...
P. Wang +5 more
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In Vitro Cellular & Developmental Biology - Animal, 2017
Avian leukemia subgroup J (ALV-J) is one of the most detrimental neoplastic diseases in poultry production. However, the differences between somatic cells and immune cells post-infection remain poorly understood. The aim of our study was to detect the different responses in chicken to infection with ALV-J in different cell lines.
Guohong, Chen +7 more
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Avian leukemia subgroup J (ALV-J) is one of the most detrimental neoplastic diseases in poultry production. However, the differences between somatic cells and immune cells post-infection remain poorly understood. The aim of our study was to detect the different responses in chicken to infection with ALV-J in different cell lines.
Guohong, Chen +7 more
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Immunochromatographic test (ICT) for the detection of antibody against ALV-J
The Thai Journal of Veterinary Medicine, 2022Guihua Wang, Yanming Wang, Ziqiang Cheng
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