Results 91 to 100 of about 1,231,896 (240)

scH16S‐Seq Maps Klebsiella pneumoniae‐Associated Myeloid States and Reveals a CD38–NAD Immunometabolic Axis That Impairs Lysosomal Acidification in Sepsis

Advanced Science, EarlyView.
Single‐cell host–bacterial 16S co‐sequencing (scH16S‐seq) integrates cell‐associated bacterial 16S‐derived signals with host transcriptomes to resolve bacterial signal‐enriched myeloid states in Klebsiella pneumoniae sepsis. Complementary pharmacological and genetic analyses define a CD38–NAD immunometabolic axis connecting mitochondrial bioenergetic ...
Yangguang Li, Yilong Yu, Fang Qin, Shenxing Li, Xuanheng Li, Peizhao Liu, Juanhan Liu, Haiqing Liu, Songqi Jing, Jianghao Zou, Sicheng Li, Jiayang Li, Tao Zheng, Yun Zhao, Jianan Ren, Xiuwen Wu   +15 more
wiley   +1 more source

Determining the mRNA quantity of selected proteins of the extracellular matrix in the alveolar bone

, 2017
The objective is to determine the mRNA quantity of selected proteins of the extracellular matrix in the alveolar bone with the help of real-time RT-PCR.
Große Steffen, Christian, Gruber, Rudolf, Georg-August-Universität Göttingen, Miosge, Nicolai, null null, Christian Große Steffen   +5 more
core   +1 more source

Influence of Masticatory Functional Loss on the Remodeling of Alveolar Bone in Rats

Open Journal of Stomatology, 2020
There is plenty of literature on masticatory function and its impact on maxillofacial development. However, the influence of masticatory hypofunction on bone turnover in the alveolar bone has hardly been studied. This study aimed to clarify the influence of tooth loss and soft diet on the alveolar bone turnover during the growth period.
Kei Ogawa, Takamichi Yamada, Norimitsu Hirai, Wataru Morita, Yurie Okada, Seiko Yamamoto-Nemoto, Takehiko Shimizu   +6 more
openaire   +2 more sources

Ultrasound‐Activated Ce(IV)‐Integrated Biomimetic Nanoplatform for Oxygenation‐Reinforced Gas‐Sonodynamic Ferroptosis and cGAS–STING‐Driven Antitumor Immunity

Advanced Science, EarlyView.
A Ce(IV)‐integrated biomimetic nanoplatform coordinates tumor oxygenation, ultrasound‐triggered carbon monoxide release, sonodynamic therapy, ferroptosis amplification, and cyclic GMP–AMP synthase (cGAS)–stimulator of interferon genes (STING) immune activation.
Mengli Ma, Yingying Wu, Yunjie Wang, Yang Li, Yijia Zhang, Zhibo Zhang, Jinzhi Peng, Xiangyu Wu, Yi Luo, Weijing Zhang, Xin Ye, Weisong Lai, Shengyu Wang, Dan Du, Wengang Li, Nan Zheng, Fanghong Luo, Ting Wu   +17 more
wiley   +1 more source

Bone anabolic agents repair alveolar bone damaged by diabetes in mice

International Journal of Oral Science
Type 2 diabetes (T2D) is a chronic metabolic disorder that significantly impacts skeletal health, including bones of the oral cavity, where alveolar bone is particularly susceptible due to its high remodeling rate and sensitivity to systemic metabolic ...
Hakan Turkkahraman, Carson Joseph Walton, Yukiko Koizumi, Tianli Zhu, Nisreen Akel, Xue Yuan, Teresita M. Bellido   +6 more
doaj   +1 more source

Evaluation of Bone Resorption Rate during Alveolar Bone Remodeling by Orthodontic Treatment.

TRANSACTIONS OF THE JAPAN SOCIETY OF MECHANICAL ENGINEERS Series C, 1995
Orthodontic treatment utilizes the biomechanical adaptive deformation of alveolar bone in response to external forces. The alveolar bone resorption rate is one of the fundamental factors for describing a remodeling process of the hard tissue. This paper describes a new estimation technique for the resorption rate during orthodontic treatment.
Morikawa, Hajime, Nishihira, Morimasa, Yamamoto, Katsuyuki, Ishikawa, Hiroyuki, Satoh, Yoshiaki, Nakamura, Shinji   +5 more
openaire   +2 more sources

Peran Matriks Metalloproteninase (MMP 9) pada Remodeling Tulang Alveolar

, 2017
Procceding Book FORKINAS VI FKG UNEJ 14th-15th 2016The alveolar bone is the bone that supported the teeth, contains the thickened ridge of bone, tooth socket, and alveoli.
Maulana, Hafiedz
core  

A Hypothalamic Oxytocinergic–Sympathetic Axis Couples Anxiety Dysregulation With Impaired Tendon–Bone Repair

Advanced Science, EarlyView.
RCI is associated with functional suppression of oxytocinergic neurons in the PVN. Reduced PVNOXT neuronal activity contributes to altered sympathetic regulation involving the IML–sympathetic chain pathway, accompanied by changes in norepinephrine signaling at the BTI.
Liyang Wan, Tingmo Huang, Liyue Zeng, Ruixue Du, Hengshuo Zhang, Shen Liu, Tao Zhang, Jianzhong Hu, Hongbin Lu   +8 more
wiley   +1 more source

The Effect of Etidronate on Alveolar Bone Remodeling in Dog Mandible

, 2001
Indiana University-Purdue University Indianapolis (IUPUI)Etidronate belongs to a class of drugs called bisphosphonates, which are prescribed for the treatment of osteoporosis and other metabolic bone diseases. The main effect of these drugs is to inhibit
Handick, Kimberly E.
core   +1 more source

Aged ZnO Nanoparticles Promote Breast Cancer Lung Metastasis by Remodeling the Pulmonary Microenvironment Through the CXCL10/Wnt/β‐Catenin Axis

Advanced Science, EarlyView.
In summary, pulmonary exposure to ZnO NPs, particularly aged NPs, promotes breast cancer metastasis by remodelling the lung tumour microenvironment. Aged ZnO NPs enrich M2‐macrophages, MDSCs and activated CAFs to form an immunosuppressive metastatic niche. CXCL10 from these cells drives metastasis via Wnt/β‐catenin activation.
Yong Zhu, Siyu Wang, Tong Lin, Jingyi Zhang, Jingya Yang, Dixiang Kang, Wenting Zhao, Na Yu, Meimei Wang   +8 more
wiley   +1 more source