Results 51 to 60 of about 1,231,896 (240)

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Isotropic continuum damage/repair model for alveolar bone remodeling

Journal of Computational and Applied Mathematics, 2010
AbstractSeveral authors have proposed mechanical models to predict long term tooth movement, considering both the tooth and its surrounding bone tissue as isotropic linear elastic materials coupled to either an adaptative elasticity behavior or an update of the elasticity constants with density evolution.
Marlene Mengoni, Jean-Philippe Ponthot
openaire   +2 more sources

The effects of alveolar decortications on orthodontic tooth movement and bone remodelling in rats [PDF]

European Journal of Orthodontics, 2017
Alveolar decortication (AD) is a minimally invasive procedure that can be performed in the orthodontic office as an intervention to accelerate tooth movement. There is a gap in the literature evaluating the earlier and delayed responses after AD using lighter orthodontic forces in a rat model.
Eliane H, Dutra, Ahmad, Ahmida, Alexandro, Lima, Sydney, Schneider, Ravindra, Nanda, Sumit, Yadav   +5 more
openaire   +2 more sources

RUNX2 promotes osteoclast differentiation and bone resorption via the newly identified LncRNA-ROD: implications for alveolar remodeling

International Journal of Oral Science
Delayed tooth eruption is a hallmark of cleidocranial dysplasia (CCD) caused by RUNX2 haploinsufficiency, yet the underlying molecular mechanism remains undefined. Here, we show that RUNX2 regulates osteoclast-mediated alveolar bone remodeling, a process
Jie Li, Yang Liu, Yanchun Qiao, Changqing Yan, Weiwei Zhao, Lingli Ji, Dandan Liu, Yuejiao Xin, Chenying Zhang, Xiaozhe Wang, Yixiang Wang, Shuguo Zheng   +11 more
doaj   +1 more source

Regulating Cells Fate and Function to Facilitate Bone Regeneration via Designing Programmable Bio‐Interactive Materials

Advanced Science, EarlyView.
This article aims to elucidate the biological mechanisms of bone repair and the evolution of material design, highlighting key cellular and molecular processes. It further proposes strategies and prospects for programmable bio‐interactive materials, which enable precisely guided bone tissue regeneration by dynamically regulating cell behavior and the ...
Qingrui Fan, Fuming Cao, Junqiang Mao, Pengbin Yin, Licheng Zhang, Jianjun Wang, Peifu Tang   +6 more
wiley   +1 more source

Lymphatic Vessels Orchestrate Immune And Lipid Homeostasis During Bone Regeneration

International Dental Journal
Aim or purpose: Lymphatic vessels play a pivotal role in fluid drainage and immune modulation; however, their precise function in alveolar bone regeneration remains unclear.
Qin Ziyue, Jiang Hongbing, Xu Rongyao
doaj   +1 more source

Bone substitute effect on vascularization and bone remodeling after application of phVEGF165 transfected BMSC [PDF]

, 2012
VEGF (vascular endothelial growth factor) promotes vascularization and remodeling of bone substitutes. The aim of this study was to examine the effect of distinct resorbable ceramic carriers on bone forming capacities of VEGF transfected bone marrow ...
Beverungen, Mirjam, Wieland, Julia, Michael Fehr, Florian Geiger, Philip Kasten, Mirjam Beverungen, Helga Lorenz, Geiger, Florian, Fehr, Michael, Lorenz, Helga, Julia Wieland, Kasten, Philip   +11 more
core   +1 more source

Image_1_CCR2+ Macrophages Promote Orthodontic Tooth Movement and Alveolar Bone Remodeling.pdf

, 2022
During mechanical force-induced alveolar bone remodeling, macrophage-mediated local inflammation plays a critical role. Yet, the detailed heterogeneity of macrophages is still unknown.
Hao Xu (6530), Shuting Zhang (436486), Bin Yan (32980), Adwait Amod Sathe (12044777), Chao Xing (28961), Jiani Guan (816942), Wen Sun (273647), Hanwen Zhang (307516), Zhichun Jin (576264)   +8 more
core   +1 more source

Matrix Stiffness Orchestrates Mesenchymal Stem Cell Lineage Commitment Toward Osteogenesis and Adipogenesis Through the PIEZO1/SP1/STC2 Axis

Advanced Science, EarlyView.
Matrix stiffness directs mesenchymal stem cell lineage commitment through PIEZO1‐dependent activation of the SP1/STC2 pathway. Stiff matrices favor osteogenesis and suppress adipogenesis, whereas the loss of PIEZO1 function impairs early bone formation. STC2 retains lineage‐regulatory activity even when PIEZO1 is inactive.
Shuo Zhang, Siteng Li, Wenzhong Chen, Qingcheng Song, Haiyue Zhao, Peng Wang, Yiran Zhang, Wenquan Liang, Shaowei Zheng, Juan Wang, Wei Chen, Yanbin Zhu, Yingze Zhang   +12 more
wiley   +1 more source

Cephalometric Evaluation of Alveolar Bone Remodeling following Anterior Teeth Retraction

, 2007
Aim To evaluate the extent of the alveolar bone remodeling after incisor retraction using lateral cephalograms. Materials and methods Lateral cephalograms of 30 patients with age of 16 years and above requiring therapeutic extraction of both maxillary ...
Darshit Dhanani, G Shivaprakash
core   +1 more source