Drug repurposing for hard-to-treat human alveolar echinococcosis: pyronaridine and beyond
ParasitologyHuman alveolar echinococcosis is a hard-to-treat and largely untreated parasitic disease with high associated health care costs. The current antiparasitic treatment for alveolar echinococcosis relies exclusively on albendazole, which does not act ...
Weisi Wang +11 more
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A monoclonal antibody against Echinococcus multilocularis Em2 antigen [PDF]
, 2017 A monoclonal antibody (MAb G11) species-specific to the Em2 antigen of Echinococcus multilocularis was generated for (i) further biological characterization of the Em2 antigen, (ii) easy affinity-purification of Em2 antigen for immunodiagnostic and ...
Deplazes, P., Gottstein, B.
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Improved serodiagnosis of alveolar echinococcosis of humans using an in vitro-produced Echinococcus multilocularis antigen [PDF]
, 2017 Serology is an important tool for the diagnosis of alveolar echinococcosis (AE) in humans. In order to improve serodiagnostic performance, we have developed an in vitro-produced Echinococcus mulilocularis metacestode vesicle fluid (EmVF) antigen for ...
FREI, E. +3 more
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EchiNam: multicenter retrospective study on the experience, challenges, and pitfalls in the diagnosis and treatment of alveolar echinococcosis in Belgium [PDF]
P Plum +13 more
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Recognising the substantial burden of neglected pandemics cystic and alveolar echinococcosis
The Lancet Global Health, 2020 Adriano Casulli
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Prevalence of Echinococcus spp. Infection Using Coproantigen ELISA among Canids of Moghan Plain, Iran [PDF]
Background: Echinococcosis is one of the most important helminthic zoonotic diseases in Iran. Intestinal Scraping Technique (IST), the traditional method for diagnosis of infection in definitive hosts, has many disadvantages including low susceptibility ...
حبیب زاده, شهرام +9 more
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Effects of inhibitor targeting the EGFR/MEK signaling pathway on the growth and development of Echinococcus multilocularis and its molecular mechanism [PDF]
, 2016 泡状棘球蚴病(Alveolarechinococcosis，AE)是由泡状棘球绦虫(Echinococcusmulticularis，Em)幼虫引起的一种致命性的人畜共患寄生虫病。目前对于泡球蚴病的治疗方法十分有限，寻找新型药物靶点十分必要。EGF/EGFR信号通路调控细胞的多种生命活动包括增殖、分化、迁移等，本文在实验室前期研究的基础上，探讨了小分子抑制剂通过对泡球蚴EGF/EGFR介导信号通路作用，对泡球蚴生长发育的影响及其机制。 本文对EGFR抑制剂CI-1033 ...
李秀
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Visualization and Pathological Characteristics of Hepatic Alveolar Echinococcosis with Synchrotron-based X-ray Phase Sensitive Micro-tomography [PDF]
, 2016 Huiqiang Liu +9 more
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