Usefulness of PCR Analysis for Diagnosis of Alveolar Echinococcosis with Unusual Localizations: Two Case Studies [PDF]
Sophie Georges+6 more
openalex +1 more source
Drug repurposing for hard-to-treat human alveolar echinococcosis: pyronaridine and beyond
Human alveolar echinococcosis is a hard-to-treat and largely untreated parasitic disease with high associated health care costs. The current antiparasitic treatment for alveolar echinococcosis relies exclusively on albendazole, which does not act ...
Weisi Wang+11 more
doaj +1 more source
Application of an in vitro drug screening assay based on the release of phosphoglucose isomerase to determine the structure-activity relationship of thiazolides against Echinococcus multilocularis metacestodes [PDF]
Objectives The disease alveolar echinococcosis (AE), caused by the larval stage of the cestode Echinococcus multilocularis, is fatal if treatment is unsuccessful.
Hemphill, Andrew+3 more
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Hepatic Alveolar Echinococcosis in Cynomolgus Monkeys (Macaca fascicularis) [PDF]
L. N. Bacciarini+4 more
openalex +1 more source
FDG-PET/MRI in alveolar echinococcosis [PDF]
Felix Lötsch+5 more
doaj +4 more sources
Effects of inhibitor targeting the EGFR/MEK signaling pathway on the growth and development of Echinococcus multilocularis and its molecular mechanism [PDF]
泡状棘球蚴病(Alveolarechinococcosis,AE)是由泡状棘球绦虫(Echinococcusmulticularis,Em)幼虫引起的一种致命性的人畜共患寄生虫病。目前对于泡球蚴病的治疗方法十分有限,寻找新型药物靶点十分必要。EGF/EGFR信号通路调控细胞的多种生命活动包括增殖、分化、迁移等,本文在实验室前期研究的基础上,探讨了小分子抑制剂通过对泡球蚴EGF/EGFR介导信号通路作用,对泡球蚴生长发育的影响及其机制。 本文对EGFR抑制剂CI-1033 ...
李秀
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Parasites in food chains [PDF]
While in high-income countries, the majority of people die from non-communicable, chronic conditions, nearly 40% of deaths in developing countries are among children under 15 years. Diarrhoea is among the top 10 leading causes of death and many cases are
Grace, Delia, Roesel, Kristina
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Dot immunogold filtration assay (DIGFA) with multiple native antigens for rapid serodiagnosis of human cystic and alveolar echinococcosis [PDF]
Xiaohui Feng+9 more
openalex +1 more source
Serological diagnosis of echinococcosis: the diagnostic potential of native antigens [PDF]
Purpose: Human alveolar (AE) and cystic echinococcosis (CE) caused by the metacestode stages of Echinococcus multilocularis and E. granulosus, respectively, lack pathognomonic clinical signs.
Bertogg, K.+6 more
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