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The alveolar macrophage is one of the few tissue macrophage populations readily accessible to study both in the human and in animals. Since harvesting of these cells by bronchoalveolar lavage was first described in 1961, alveolar macrophages have been extensively investigated.
A O, Fels, Z A, Cohn
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Cellular Immunology, 2018
Alveolar macrophages are the most abundant innate immune cells in the distal lung parenchyma, located on the luminal surface of the alveolar space. They are the first to encounter incoming pathogens and pollutants and to help orchestrate the initiation and resolution of the immune response in the lung.
Nikita, Joshi +2 more
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Alveolar macrophages are the most abundant innate immune cells in the distal lung parenchyma, located on the luminal surface of the alveolar space. They are the first to encounter incoming pathogens and pollutants and to help orchestrate the initiation and resolution of the immune response in the lung.
Nikita, Joshi +2 more
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Hospital Practice, 1990
Alveolar macrophages play important roles in lung homeostatic and defense mechanisms. These essential physiologic functions, however, may be subverted. What influences the cells one way or the other? Recent evidence is reviewed. Many of the relevant stimulatory and inhibitory factors are produced by alveolar macrophages themselves.
A, Holian, R K, Scheule
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Alveolar macrophages play important roles in lung homeostatic and defense mechanisms. These essential physiologic functions, however, may be subverted. What influences the cells one way or the other? Recent evidence is reviewed. Many of the relevant stimulatory and inhibitory factors are produced by alveolar macrophages themselves.
A, Holian, R K, Scheule
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THE PULMONARY ALVEOLAR MACROPHAGE
Australian and New Zealand Journal of Medicine, 1984Abstract:The pulmonary alveolar macrophage (PAM) occupies a unique environment, with exposure to both the atmosphere and the blood stream. This position enables the PAM to perform its primary role of protecting the lung from inhaled, potentially damaging, agents.
G, McLennan, N, DeYoung
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Micronuclei in Human Alveolar Macrophages
Respiration, 2009Occurrence of micronuclei was monitored in pulmonary alveolar macrophages collected from 31 individuals undergoing diagnostic bronchoalveolar lavage. The overall frequency of micro nucleated cells was 3.88 ± 1.84%₀, without any significant difference attributable to sex, age, pathology, occupation, or smoking habits.
D'AGOSTINI, FRANCESCO +3 more
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Inhibition of alveolar macrophages by pentoxifylline
Critical Care Medicine, 1991Pentoxifylline can inhibit blood leukocyte functions in vitro, and some inflammatory processes in the lung in vivo. Therefore, we examined the effects of pentoxifylline on alveolar macrophage functions in vitro. Alveolar macrophages were harvested from normal rat lungs by airway lavage.
J H, Williams +3 more
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1960
The alveolar macrophages, or dust cells, of the lung are cells which lie free within the air spaces of the lung alveoles. They have been extensively studied in the light microscope [for summary see (1)]. Their phagocytic potentialities are likewise known from light microscopic studies, in which dyes, India ink, or oils were injected into the trachea of
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The alveolar macrophages, or dust cells, of the lung are cells which lie free within the air spaces of the lung alveoles. They have been extensively studied in the light microscope [for summary see (1)]. Their phagocytic potentialities are likewise known from light microscopic studies, in which dyes, India ink, or oils were injected into the trachea of
openaire +1 more source

