Trained Immunity Attenuates Bleomycin-Induced Pulmonary Fibrosis by Promoting AMPK-Mediated Autophagy in Alveolar Macrophages. [PDF]
Wang X, Guo X, Meng H, Sun Z.
europepmc +1 more source
Ac‐SDKP modulates apoptosis via HSP27 and the FAS/FASL and mitochondrial axes
Schematic diagram of Ac‐SDKP regulating the FAS/FASL and mitochondrial apoptosis pathways via HSP27. Ac‐SDKP inhibits HSP27 expression, activates the FAS/FASL pathway and Caspase‐3 signaling, increases Caspase‐8 and Caspase‐3 expression, and induces cell apoptosis.
Wenxin Guo +13 more
wiley +1 more source
RANKL-RANK signaling promotes cigarette smoke-induced emphysema with MMP-9 upregulation in alveolar macrophages. [PDF]
Zhou L +4 more
europepmc +1 more source
Marine‐derived type I collagen is extracted from Scyliorhinus canicula skin and characterized by physicochemical and morphological analyses. The collagen exhibits excellent biocompatibility, promotes wound healing, reduces inflammatory mediators, and inhibits melanogenesis.
Marwa Rejeb +6 more
wiley +1 more source
Nrf2 Activation Alleviates Silica-Induced Toxicity in Alveolar Macrophages via Glutamine Metabolic Reprogramming. [PDF]
Zhu X +7 more
europepmc +1 more source
The miniSdd7‐BE4max‐SpG system enables highly efficient multiplex C‐to‐T base editing of APN, CD163, and MSTN in porcine fibroblasts, providing a robust platform for future development of multiplex gene‐edited livestock. ABSTRACT Efficient multiplex genome editing is essential for improving complex traits in livestock that are governed by multiple ...
Shaoshuai Wang +4 more
wiley +1 more source
UBE2M deficiency in alveolar macrophages promotes emphysema through HIF-2α/MMP12 axis. [PDF]
Li Z +12 more
europepmc +1 more source
The Cytokine TGF‐&bgr; Promotes the Development and Homeostasis of Alveolar Macrophages
Xue-Yan Yu +6 more
semanticscholar +1 more source
Human Fibroblast–Myeloid Cell Tissue Atlas Across the Lungs, Synovium, Skin, and Heart
Objective The availability of single‐cell RNA sequencing (scRNAseq) data in different tissues and disease states provides an opportunity to compare cellular subsets and identify common and unique cellular activation. In this study, we aimed to characterize shared and tissue‐specific myeloid and stromal phenotypes and to uncover key cellular subtypes ...
Lucy MacDonald +9 more
wiley +1 more source
Effects of Chlorogenic Acid on Deoxynivalenol (DON)-Induced Ferroptosis in Porcine Alveolar Macrophages. [PDF]
Zhang J +5 more
europepmc +1 more source

