Results 261 to 270 of about 1,184,873 (292)

Exosomal microRNAs from Alveolar Macrophages Reveal a Protective Role of the Lung Microbiome Against Oncogenic Signaling During PAH Exposure. [PDF]

Cells
Chandra H, Yadav B, Kuhnell D, Langevin S, Biesiada J, Medvedovic M, Yadav JS.   +6 more
europepmc   +1 more source

Ginsenoside Rg1 Ameliorates LPS‐Induced Sepsis‐Associated Lung Injury in Mice via VEGFC/D‐VEGFR3 Signaling‐Mediated Lymphangiogenesis and Lymphatic Remodeling

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Sepsis‐induced acute lung injury (ALI) remains challenging to treat, with conventional anti‐inflammatory therapies offering limited efficacy. The lymphatic system is crucial for removing edema and inflammatory mediators, and its impairment can exacerbate lung injury.
He Wang, Lan Hu, Chun‐Pan Zhang, Wen‐Jie Qi, Yu‐Guo Song   +4 more
wiley   +1 more source

Microbiota-induced EI24 improves homeostasis but impedes function of alveolar macrophages via metabolic regulation. [PDF]

Nat Commun
Huang Y, Su M, Zhang Y, Pan J, Wang Y, Chen D, Chen X, Tian C, Zhang H, Sun Q, Yuan L, Fu B, Jiang W, Li S, Xie D, Bai L.   +15 more
europepmc   +1 more source

Toxicity Differences Between Microplastics and Nanoplastics in Organs: From Molecular Mechanisms to Potential Therapeutic Strategies

Med Research, EarlyView.
This review systematically compares the size‐dependent toxicity of microplastics and nanoplastics in the intestine, liver, kidney, lung, and brain. Particle size determines bioavailability, barrier penetration, and injury mechanisms. Because of their small size and high surface reactivity, NPs readily cross the intestinal epithelium and blood–brain ...
Yixian Cheng, Junjie Chen, Rui Fu, Jiawei Zhang, Jianguang Jia, Wei Wang, Zheng Zhang, Peng Zhang, Haosong Chen, Huake Cao, Gang Li, Weiwei Sheng, Ting Li, Bo Chen, Guodong Cao   +14 more
wiley   +1 more source

Phagocytosis of <i>Mycobacterium fortuitum</i> by Caprine Alveolar Macrophages Is Associated with iNOS and Pro-Inflammatory Markers Expression. [PDF]

Int J Mol Sci
Blay-Benach M, Cuenca-Lara P, Repullés J, Cervera Z, Pérez de Val B.   +4 more
europepmc   +1 more source

Recent Advances in Exosome‐Based Nanodelivery Systems for Traumatic Brain Injury Treatment

Med Research, EarlyView.
An overview of functional modification, therapeutic effects, molecular composition, and delivery strategies for exosomes. ABSTRACT Traumatic brain injury (TBI) is a highly heterogeneous neurological condition with extremely high rates of mortality and disability.
Jue Zhu, Weiquan Liao, Ziqi Lian, Mengdan Zhang, Chenxing Wang, Xingjia Zhu, Lin Zhang, Jian Chen, Zhichao Lu, Peipei Gong   +9 more
wiley   +1 more source

Unveiling the immunomodulatory properties of starch microparticles on alveolar macrophages. [PDF]

PLoS One
Barrera-Rosales A, Mata-Espinosa D, Villegas-Ruiz V, Silva-Miranda M, Zenteno E, Sánchez S, Hernández-Pando R, Rodríguez-Sanoja R, Moreno-Mendieta S.   +8 more
europepmc   +1 more source

Alveolar macrophages initiate the spatially targeted recruitment of neutrophils after nanoparticle inhalation. [PDF]

Sci Adv
Liu Q, Yang L, Li C, Han L, Wilmot J, Yang G, Leinardi R, Zhou Q, Schröppel A, Kutschke D, Secklehner J, Yldirim AÖ, Huaux F, Zeuschner D, Carlin LM, Sperandio M, Schmid O, Stoeger T, Rehberg M.   +18 more
europepmc   +1 more source

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

Medicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli, Alessia Merra, Chiara Marraccini, Lucia Merolle, Graziella Pellegrini, Eleonora Maurizi   +5 more
wiley   +1 more source

RNA-seq evaluation of equine alveolar macrophages and monocyte-derived macrophages exposed to an inflammatory stimulus (short communication). [PDF]

BMC Vet Res
Kang H, Lee GKC, Bienzle D, Hammermüller J, Arroyo LG, Lillie BN, Beeler-Marfisi J.   +6 more
europepmc   +1 more source