Results 221 to 230 of about 9,882,917 (355)

An Investigation of the Efficacy of Curcumin for Treatment of Alzheimer's Disease

, 2016
Parantap Patel
openalex   +2 more sources

Longitudinal brain metabolic changes from amnestic mild cognitive impairment to Alzheimer's disease [PDF]

, 2009
Marine Fouquet, Béatrice Desgranges, Brigitte Landeau, Édouard Duchesnay, Florence Mézenge, Vincent de La Sayette, Fausto Viader, Jean‐Claude Baron, Francis Eustache, Gaël Chételat   +9 more
openalex   +1 more source

Parabiosis, Assembloids, Organoids (PAO)

Advanced Science, EarlyView.
This review evaluates parabiosis, organoids, and assembloids as complementary disease models spanning systemic, organ, and multi‐organ levels. It highlights their construction strategies, applications, and current limitations, while emphasizing their integration with frontier technologies such as artificial intelligence, organ‐on‐a‐chip, CRISPR, and ...
Yang Hong, Lavonda Li, Lijie Yan, Long Bai, Jiacan Su, Xingcai Zhang   +5 more
wiley   +1 more source

Subjects harboring presenilin familial Alzheimer's disease mutations exhibit diverse white matter biochemistry alterations.

, 2013
Alex E. Roher, Chera L. Maarouf, Michael Malek‐Ahmadi, Jeffrey S. Wilson, Tyler A. Kokjohn, Ian D. Daugs, Charisse M. Whiteside, Walter M. Kalback, Mi Mi P. Macias, Sandra A. Jacobson, Marwan N. Sabbagh, Bernardino Ghetti, Thomas G. Beach   +12 more
openalex   +1 more source

Commentary on “Ferroptosis, M6A and immune checkpoint-related gene expression in the middle temporal gyrus of the Alzheimer's disease brain”

Ziyu Liu, Suhang Shang
openalex   +1 more source

Pathways towards and away from Alzheimer's disease

Nature, 2004
M. Mattson
semanticscholar   +1 more source

Microglial HVCN1 Deficiency Improves Movement and Survival of SOD1G93A ALS Mice by Enhancing Microglial Migration and Neuroprotection

Advanced Science, EarlyView.
Hydrogen voltage gated channel 1 (HVCN1) is upregulated in microglia of both ALS patients and its mouse model. HVCN1 deficiency enhances microglial migration via suppressing Akt signaling, promotes neurotrophic capacity and motor function, and prolongs survival of the SOD1G93A ALS mice. This study identifies HVCN1 as a novel, promising druggable target
Fan Wang, Ke‐Yu Zhang, Lang‐Jian Zhu, Wei‐Jue Li, Yang Wu, Xiang Gao, Xiao‐Ru Ma, Xiu‐Hua Yin, Jian‐Bin Wu, Xiao‐Kang Ye, Zhao‐Jun Dong, Di‐Xian Wang, Zhe Zhou, Shao‐Dong Wang, Lei Han, Zhi‐Nong Jiang, Jing‐Wei Zhao   +16 more
wiley   +1 more source

Single-cell transcriptomic analysis of Alzheimer’s disease

Nature, 2019
Hansruedi Mathys, J. Dávila-Velderrain, Zhuyu Peng, Fan Gao, S. Mohammadi, Jennie Z. Young, M. Menon, Liang He, Fatema Abdurrob, Xueqiao Jiang, Anthony J. Martorell, R. Ransohoff, B. Hafler, D. Bennett, Manolis Kellis, L. Tsai   +15 more
semanticscholar   +1 more source

Olfactory‐to‐Entorhinal Network Dysrhythmias Drive Parkinson's Cognitive Impairment Through Frequency‐Specific Oscillatory Decoupling

Advanced Science, EarlyView.
Wang et al reveal that in the olfactory system, the selective impairment of gamma‐driven Barcode features underlying early olfactory deficits, while the selective impairment of theta‐driven Barcode features underlying later cognitive deficits, further establishing cross‐network gamma oscillations in the early stage as a biomarker of later cognitive ...
Shuaishuai Wang, Zhishen Cai, Xingfeng Mao, Yixuan Zhang, Yunlong Pan, Jiawen Cheng, Xuechun Wang, Hengyi Song, Sasaki Takuya, Ming Lu, Gang Hu, Xiuxiu Liu, Yingmei Lu, Feng Han   +13 more
wiley   +1 more source

Variant of TREM2 associated with the risk of Alzheimer's disease.

New England Journal of Medicine, 2013
Thorlákur Jónsson, H. Stefánsson, S. Steinberg, I. Jónsdóttir, Pálmi V. Jónsson, J. Snaedal, Sigurbjorn Bjornsson, J. Huttenlocher, A. Levey, J. Lah, D. Rujescu, H. Hampel, I. Giegling, O. Andreassen, K. Engedal, I. Ulstein, S. Djurovic, C. Ibrahim-Verbaas, A. Hofman, M. Ikram, C. V. van Duijn, U. Thorsteinsdóttir, A. Kong, K. Stefánsson   +23 more
semanticscholar   +1 more source