Results 221 to 230 of about 9,372,438 (357)

Single-cell transcriptomic analysis of Alzheimer’s disease

Nature, 2019
Hansruedi Mathys, J. Dávila-Velderrain, Zhuyu Peng, Fan Gao, S. Mohammadi, Jennie Z. Young, M. Menon, Liang He, Fatema Abdurrob, Xueqiao Jiang, Anthony J. Martorell, R. Ransohoff, B. Hafler, D. Bennett, Manolis Kellis, L. Tsai   +15 more
semanticscholar   +1 more source

Nanoplasmonic Infrared Microarray Sensor Enabling Structural Protein Biomarker‐Based Drug Screening for Neurodegenerative Diseases

Advanced Science, EarlyView.
This work introduces an on‐chip, integrated plasmonic infrared microarray sensor that enables high‐throughput, label‐free drug screening targeting structural protein biomarkers in neurodegenerative diseases. Through ultra‐compact microwell arrays, the sensor achieves ultra‐sensitive, rapid, and multiplexed secondary structural analysis of the effect of
Deepthy Kavungal, Enzo Morro, Senthil T Kumar, Berkay Dagli, Hilal A Lashuel, Hatice Altug   +5 more
wiley   +1 more source

Human antibodies reactive with beta-amyloid protein in Alzheimer's disease. [PDF]

, 1993
Felicia Gaskin, J Finley, Qiang Fang, S. Xu, Shu Man Fu   +4 more
openalex   +1 more source

Inhibition of Phosphodiesterase 10A by MP‐10 Rescues Behavioral Deficits and Normalizes Microglial Morphology and Synaptic Pruning in A Mouse Model of FOXP1 Syndrome

Advanced Science, EarlyView.
We demonstrate that Foxp1± mice, modeling FOXP1 haploinsufficiency, exhibit behavioral deficits, striatal neuroinflammatory changes including altered microglial complexity and synaptic pruning, and markedly reduced Pde10a expression. Pde10a inhibition starting immediately after birth restores Foxp1± behavior, microglial morphology, and pruning ...
Henning Fröhlich, Jing Wang, Ferdinand Althammer, Tim Schubert, Nina Kluck, Valery Grinevich, Stefanie Schmitteckert, Christian P. Schaaf, Gudrun A. Rappold   +8 more
wiley   +1 more source

Correction to "Resilience in Alzheimer's disease: Impact of operationalization and methodological choices". [PDF]

Alzheimers Dement
europepmc   +1 more source

The clinical translation of blood biomarkers for Alzheimer's disease: Timing and challenges. [PDF]

Alzheimers Dement
Huang S, Wang J, Guo T, Wang YJ.
europepmc   +1 more source

Changes in Semantic Memory in Early Stage Alzheimer's Disease Patients [PDF]

, 1993
Herbert J. Weingartner, Claudia H. Kawas, Robert R. Rawlings, M.J Shapiro   +3 more
openalex   +1 more source

Bacteroides Fragilis‐Derived Outer Membrane Vesicles Deliver MiR‐5119 and Alleviate Colitis by Targeting PD‐L1 to Inhibit GSDMD‐Mediated Neutrophil Extracellular Trap Formation

Advanced Science, EarlyView.
Bacteroides fragilis‐derived outer membrane vesicles deliver miR‐5119 and alleviate colitis by targeting PD‐L1 to inhibit GSDMD‐mediated neutrophil extracellular trap formation. Abstract Inflammatory bowel disease (IBD) results from a breakdown in the symbiotic relationship between the intestinal commensal microflora and the mucosal immune system.
Yi Yang, Lanmengxi Yang, Yilin Yang, Haiyi Deng, Shiyu Su, Yinxiao Xia, Jin Su, Yuheng Liu, Junwei Wu, Jing Zhang, Yao Liao, Lifu Wang   +11 more
wiley   +1 more source

Allostatic load dynamics, Alzheimer's disease biomarkers, and progression in individuals with mild cognitive impairment: findings from the Alzheimer's Disease Neuroimaging Initiative. [PDF]

Alzheimers Dement (Amst)
Souza-Talarico JN, Perkhounkova Y, Hein M, Lee J, Hefti M, Sindi S.   +5 more
europepmc   +1 more source

Association of heparan sulfate proteoglycan with the neurofibrillary tangles of Alzheimer's disease [PDF]

, 1991
George Perry, SL Siedlak, Peggy L. Richey, Mitsuru Kawai, Patrick Cras, RN Kalaria, Galloway Pg, J. Marian Scardina, Barbara Cordell, BD Greenberg   +9 more
openalex   +1 more source