Results 171 to 180 of about 9,650,018 (348)

PND61 LITERATURE REVIEW ON THE POTENTIAL SOCIETAL IMPACT OF DISEASE-MODIFYING THERAPIES IN ALZHEIMER€™S DISEASE [PDF]

Value in Health, 2019
H. Wieffer, T. Mantopoulos, G. Spentzouris, C. Quinn, T. Dort, R. Thompson   +5 more
openaire   +1 more source

Additional file 1: of Attitudes toward clinical trials across the Alzheimerâ s disease spectrum

, 2017
Appendix. (DOC 59 kb)
NuĂąo, Michelle, Gillen, Daniel, Dosanjh, Kulwant, Brook, Jenny, Elashoff, David, Ringman, John, Grill, Joshua   +6 more
openaire   +1 more source

Redox‐Active Polyphenol Red Molecularly Imprinted Polymers on Porous Gold Electrodes for Ultrasensitive, AI‐Assisted Detection of Alzheimer's Biomarkers in Undiluted Biofluids

Advanced Healthcare Materials, EarlyView.
This work presents a low‐cost, reagent‐free point‐of‐care biosensor integrating redox‐active polyphenol red molecularly imprinted polymers (pPhR MIPs) on highly porous gold (HPG) electrodes for ultrasensitive detection of phosphorylated tau 181 (p‐Tau 181), an Alzheimer’s disease biomarker, in undiluted biofluids.
Sudhaunsh Deshpande, Ajith Mohan Arjun, Guoyi Liu, Kryztof Pawlak, Sanjiv Sharma   +4 more
wiley   +1 more source

Promising Effect of Fish Oil against Alzheimer’s Disease [PDF]

Journal of Pharmaceutical and Pharmacological Sciences, 2017
openaire   +1 more source

Investigating Therapeutic Strategies in a Preclinical Model for Alzheimer’s Disease

, 2017
Alzheimer’s disease (AD) is a worldwide, incurable disease, and the most common form of dementia. Numbers of cases are rising, and since its discovery the only approved medications have treated only the symptoms, not the pathological cause. With the cost to society rising, the debilitating nature of the disease and the pressure put on the family ...
openaire   +1 more source

Additional file 8: of Beneficial effects of curtailing immune susceptibility in an Alzheimerâ s disease model

, 2019
Table S1. List of all antibodies used, with respective working dilutions for either WB or IHF, as well as Companies of origin and catalog number specification. (PDF 290 kb)
Benedetto, Giulia Di, Burgaletto, Chiara, Carta, Anna, Saccone, Salvatore, Lempereur, Laurence, Mulas, Giovanna, Loreto, Carla, Bernardini, Renato, Cantarella, Giuseppina   +8 more
openaire   +1 more source

Molecular Simulations of Polymer‐based Drug Nanocarriers: From Physical and Structural Properties to Controlled Release

Advanced Healthcare Materials, EarlyView.
Polymer‐based drug delivery systems can effectively overcome the limitations of free drugs in terms of solubility, stability, and plasma half‐life, yet their development has traditionally relied on time‐consuming trial‐and‐error approaches. This review highlights recent advances in applying molecular simulation to the design of polymer‐based drug ...
Ping Gao, Xin Jiang, Jinyu Li, Julien Nicolas, Tâp Ha‐Duong   +4 more
wiley   +1 more source

A Unique Microglia Type Associated with Restricting Development of Alzheimer’s Disease

Cell, 2017
Hadas Keren-Shaul, A. Spinrad, A. Weiner, O. Matcovitch-Natan, Raz Dvir-Szternfeld, Tyler K. Ulland, Eyal David, K. Baruch, David Lara-Astaiso, Beáta Tóth, S. Itzkovitz, M. Colonna, M. Schwartz, I. Amit   +13 more
semanticscholar   +1 more source

Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs

Advanced Healthcare Materials, EarlyView.
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner, Stefan Keim, Soheil Haddadzadegan, Odile Fernandez Romero, Katrin Zöller, Gabriel Stern, Ilaria Cesi, Krum Kafedjiiski, Andreas Bernkop‐Schnürch   +8 more
wiley   +1 more source

Clinical diagnosis of Alzheimer's disease: Report of the NINCDS—ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease

Neurology, 2011
G. Mckhann, D. Drachman, M. Folstein, R. Katzman, D. Price, E. Stadlan   +5 more
semanticscholar   +1 more source