Results 161 to 170 of about 647,233 (310)

Impact of Plasma p‐tau181 on Cognition, Motor Phenotypes, and Disease Course in ALS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Phosphorylated tau181 (p‐tau181), an Alzheimer's disease biomarker, was recently evaluated in amyotrophic lateral sclerosis (ALS). We investigated plasma p‐tau181 in 202 ALS/ALS‐FTD patients and 94 healthy controls, assessing cognitive performance, motor function, and longitudinal dynamics.
Elisabeth Kasper, Annaliis Lehto, Nina Nordmann, Oliver Peters, Julian Hellmann, Josef Priller, Eike Jakob Spruth, Gabor C. Petzold, Ina Vogt, Patrick Weydt, Sarah Bernsen, Elisabeth Dinter, Björn Falkenburger, René Günther, Emrah Düzel, Wenzel Glanz, Matthis Synofzik, Lukas Beichert, Annika Spottke, Michael Wagner, Frederic Brosseron, Matthias C. Schmid, Anja Schneider, Stefan Teipel, Johannes Prudlo, Andreas Hermann   +25 more
wiley   +1 more source

PND61 LITERATURE REVIEW ON THE POTENTIAL SOCIETAL IMPACT OF DISEASE-MODIFYING THERAPIES IN ALZHEIMER€™S DISEASE [PDF]

Value in Health, 2019
H. Wieffer, T. Mantopoulos, G. Spentzouris, C. Quinn, T. Dort, R. Thompson   +5 more
openaire   +1 more source

Additional file 1: Table S1. of Increased cerebrospinal fluid soluble TREM2 concentration in Alzheimerâ s disease

, 2016
Details of patients with other neurodegenerative diseases. (DOCX 13 kb)
Heslegrave, Amanda, Heywood, Wendy, Paterson, Ross, Magdalinou, Nadia, Svensson, Johan, Johansson, Per, ÖHrfelt, Annika, Blennow, Kaj, Hardy, John, Schott, Jonathan, Mills, Kevin, Zetterberg, Henrik   +11 more
openaire   +1 more source

Enhanced Strength and Corrosion Resistance of Ti‐13Nb‐12Ta‐10Zr‐4Sn Alloy by Aging Treatment

Advanced Engineering Materials, EarlyView.
This work systematically investigates the effect of aging treatment on mechanical properties and corrosion behavior of vacuum arc‐melted Ti‐13Nb‐12Ta‐10Zr‐4Sn alloy. Owing to the increased α″ martensite, strength and corrosion resistance were significantly enhanced by aging treatment.
Yuhua Li, Rong Zhao, Qian Zhang, Haojie Wang, Yujing Liu, Lai‐Chang Zhang   +5 more
wiley   +1 more source

Caregiver Burden and Perceived Health Competence when Caring for Family Members Diagnosed with Alzheimer’s Disease and Related Dementia [PDF]

, 2015
Purpose: To identify if there is a relationship between perceived health competence and burden of care of informal caregivers of family members with Alzheimer’s Disease and Related Dementia (ADRD).
Bailes, Christine
core  

MOESM2 of Patterns of Chinese medicine use in prescriptions for treating Alzheimerâ s disease in Taiwan

, 2016
Additional file 2. The approval Letter from National Institutes of Health.
Shun-Ku Lin, Sui-Hing Yan, Jung-Nien Lai, Tung-Hu Tsai   +3 more
openaire   +1 more source

Strategies for Loading and Releasing Peptide Therapeutics in Biodegradable Carriers

Advanced Functional Materials, EarlyView.
A biodegradable carrier‐based peptide delivery system is a powerful treatment platform for diverse diseases, owing to its superior therapeutic efficacy and low toxicity. This review examines the conventional peptide‐loaded carrier fabrication process and its current limitations.
Wookyoung Jang, Ki Wan Bong
wiley   +1 more source

Advanced 3D Platforms for Modeling CNS Neuroinflammation: Cell Integration, Techniques, and Challenges

Advanced Healthcare Materials, EarlyView.
This review summarizes the roles of key central nervous system cell types, the extracellular matrix, and the blood‐brain barrier in neuroinflammation, and their integration into diverse 3D culture systems. It examines major incorporation strategies, including direct co‐culture, hydrogel encapsulation, transwell migration assays, and bioprinting ...
Emmanuelle D. Aiyegbusi, Julia Di Stefano, Dearbhaile Dooley   +2 more
wiley   +1 more source

Additional file 1: of Neuronally derived extracellular vesicles: an emerging tool for understanding Alzheimerâ s disease

, 2019
Table S1. Proteins related to neuronally derived EVs of Alzheimerâ s disease patients (DOCX 95 kb)
Watson, Luke, Hamlett, Eric, Stone, Tyler, Sims-Robinson, Catrina   +3 more
openaire   +1 more source

Small Extracellular Vesicles from Neural Cells: Physiological and Pathological Roles, and Potential in Neurodegenerative Therapy

Advanced Healthcare Materials, EarlyView.
Neural cell–derived small extracellular vesicles (sEVs) are emerging as pivotal mediators in neurodegenerative diseases, exerting both pathogenic and therapeutic functions. This review synthesizes current evidence on how sEVs from distinct neural cell types regulate neurodegeneration, neuroprotection, biomarker discovery, and targeted drug delivery ...
Muhammad Waqas Salim, Wei Zhang, Lyndsey Collins‐Praino, Yuling Wang, Andrew Care   +4 more
wiley   +1 more source