Results 151 to 160 of about 647,233 (310)

Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons   +33 more
wiley   +1 more source

Additional file 5: of Beneficial effects of curtailing immune susceptibility in an Alzheimerâ s disease model

open access: yes, 2019
Figure S5. Co-localization of CD3 and FoxP3 in the human AD brain. Immunofluorescence in representative samples for both molecules was detected in immune cells in the hippocampus of AD patients, whereas it was absent in the brain of healthy individuals (merge column; DAPIâ =â nuclear staining).
Benedetto, Giulia Di   +8 more
openaire   +1 more source

Aquaporin‐4 in Narcolepsy Type 1: Investigation of Perivascular Fluid Movement in Sleep Disorders

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Narcolepsy type 1 (NT1) is caused by the loss of hypocretin‐1 leading to excessive daytime sleepiness and cataplexy. Additionally, disrupted nighttime sleep has become an increasingly recognized feature of NT1. As the glymphatic fluid movement has been linked to sleep architecture, we investigated cerebrospinal fluid (CSF) Aquaporin‐4 (AQP4 ...
Jonas Ranke   +5 more
wiley   +1 more source

Promising Effect of Fish Oil against Alzheimer’s Disease [PDF]

open access: yesJournal of Pharmaceutical and Pharmacological Sciences, 2017
openaire   +1 more source

MOESM2 of Histone post-translational modifications in frontal cortex from human donors with Alzheimerâ s disease

open access: yes, 2015
Additional file 2: Table S2. MRM transitions used for identification.
Anderson, Kyle, Illarion Turko
openaire   +1 more source

Anti‐CD19 CAR T Cells in Autoimmune Encephalitis: Inflammation Controlled, Neurodegeneration Unchecked?

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Just recently, successful chimeric antigen receptor (CAR) T cell therapy was reported in the first patient with refractory, anti‐diacylglycerol lipase alpha (DAGLA) antibody‐mediated autoimmune encephalitis, achieving partial clinical remission.
Dimitrios Mougiakakos   +9 more
wiley   +1 more source

Gene module-trait network analysis uncovers cell type specific systems and genes relevant to Alzheimer's Disease

open access: yesActa Neuropathologica Communications
Alzheimer’s Disease (AD) is marked by the accumulation of pathology, neuronal loss, and gliosis and frequently accompanied by decline in cognition.
Katia de Paiva Lopes   +11 more
doaj   +1 more source

Investigating Therapeutic Strategies in a Preclinical Model for Alzheimer’s Disease

open access: yes, 2017
Alzheimer’s disease (AD) is a worldwide, incurable disease, and the most common form of dementia. Numbers of cases are rising, and since its discovery the only approved medications have treated only the symptoms, not the pathological cause. With the cost to society rising, the debilitating nature of the disease and the pressure put on the family ...
openaire   +1 more source

MOESM1 of Histone post-translational modifications in frontal cortex from human donors with Alzheimerâ s disease

open access: yes, 2015
Additional file 1: Table S1. Donor information.
Anderson, Kyle, Illarion Turko
openaire   +1 more source

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