Results 131 to 140 of about 5,180,843 (313)

Additional file 1: of Rubidium and potassium levels are altered in Alzheimerâ s disease brain and blood but not in cerebrospinal fluid

, 2016
ROC analysis of Rb & K levels in plasma (Figure S1) and platelets (Figure S2). (DOCX 1297 kb)
Roberts, Blaine, Doecke, James, Rembach, Alan, L. YĂŠvenes, Fowler, Christopher, McLean, Catriona, Lind, Monica, Volitakis, Irene, Masters, Colin, Bush, Ashley, Hare, Dominic   +10 more
openaire   +1 more source

Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs, Marcel Naumann, Annaliis Lehto, Hanna Schön, Jens Kurth, Johannes Prudlo, Andreas Hermann, Elisabeth Kasper   +7 more
wiley   +1 more source

Synaptic and memory dysfunction induced by tau oligomers is rescued by up-regulation of the nitric oxide cascade

Molecular Neurodegeneration, 2019
Background Soluble aggregates of oligomeric forms of tau protein (oTau) have been associated with impairment of synaptic plasticity and memory in Alzheimer’s disease.
Erica Acquarone, Elentina K. Argyrousi, Manon van den Berg, Walter Gulisano, Mauro Fà, Agnieszka Staniszewski, Elisa Calcagno, Elisa Zuccarello, Luciano D’Adamio, Shi-Xian Deng, Daniela Puzzo, Ottavio Arancio, Jole Fiorito   +12 more
doaj   +1 more source

Additional file 1: Table S1. of Disease-related determinants are associated with mortality in dementia due to Alzheimerâ s disease

, 2018
Cox proportional hazard models using nonimputed data; influence of baseline characteristics and medical history on survival status. Table S2. Cox proportional hazard models based on nonimputed data; influence of CSF and MRI on survival status. (DOCX 26 kb)
Rhodius-Meester, Hanneke, Liedes, Hilkka, Koene, Ted, Lemstra, Afina, Teunissen, Charlotte, Barkhof, Frederik, Scheltens, Philip, van Gils, Mark, LĂśtjĂśnen, Jyrki, van der Flier, Wiesje   +9 more
openaire   +1 more source

Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the utility, accessibility, and equivalence to supervised scales of online cognitive assessment in older individuals with cognitive impairment. Methods Patients with Alzheimer's disease (AD, n = 31), idiopathic normal pressure hydrocephalus (iNPH, n = 26), and traumatic brain injury (TBI, n = 23) completed online cognitive ...
Martina Del Giovane, Valentina Giunchiglia, Michael C. B. David, Magdalena A. Kolanko, William R. Trender, Peter J. Hellyer, Harmeena Kaur, David J. Sharp, Christopher Carswell, Paresh A. Malhotra, Adam Hampshire   +10 more
wiley   +1 more source

Additional file 1: of Bapineuzumab for mild to moderate Alzheimerâ s disease: a meta-analysis of randomized controlled trials

, 2017
Shows the reasons for exclusion of retrieved articles during full text screening. (DOCX 31 kb)
Abdelrahman Abushouk, Elmaraezy, Ahmed, Aglan, Amro, Reham Salama, Fouda, Samar, Fouda, Rana, AlSafadi, Ammar   +6 more
openaire   +1 more source

The Multiple Sclerosis Severity Allele rs10191329A and Cognitive Function: A UK Biobank Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The genome‐wide association study of Multiple Sclerosis severity linked the genetic variant rs10191329A to long‐term disability and implicated brain resilience as a determinant of outcome. We hypothesised that rs10191329A might influence cognition in other neurological diseases and healthy controls.
Ioanna Zimianiti, Sheena Waters, Adil Harroud, Pernilla Stridh, Ruth Dobson, Benjamin M. Jacobs   +5 more
wiley   +1 more source

Topological Measurements of DWI Tractography for Alzheimer’s Disease Detection [PDF]

, 2017
Neurodegenerative diseases affect brain morphology and connectivity, making complex networks a suitable tool to investigate and model their effects. Because of its stereotyped pattern Alzheimer’s disease (AD) is a natural benchmark for the study of novel
Alfonso Monaco, Nicola Amoroso, Sabina Tangaro, Alzheimer’s Disease Neuroimaging Initiative   +3 more
core   +1 more source

Clinical validation of new alzheimer disease diagnosis tools based on plasma p-Tau217

Scientific Reports
Nowadays, there is an unmet need for reliable and minimally-invasive diagnosis tools capable of detecting Alzheimer’s disease at early stages. Such tools could significantly reduce the reliance on confirmatory tests that are invasive and costly, such as ...
Aleix Martí-Navia, Lourdes Álvarez-Sánchez, Laura Ferré-González, Alejandro López, Carmen Peña-Bautista, Ángel Balaguer, Nevenka Pedrosa, Helena Vico, Miguel Baquero, Consuelo Cháfer-Pericás   +9 more
doaj   +1 more source

Additional file 7: Figure S2. of Gender differences in white matter pathology and mitochondrial dysfunction in Alzheimerâ s disease with cerebrovascular disease

, 2016
Structural alignment of human and bovine MBP sequences. EMBOSS_001 corresponds to human MBP and MBP_Bovine corresponds to bovine MBP. (PDF 231Â kb)
Gallart-Palau, Xavier, Lee, Benjamin, Adav, Sunil, Jingru Qian, Serra, Aida, Park, Jung, Lai, Mitchell, Chen, Christopher, Kalaria, Raj, Siu Sze   +9 more
openaire   +1 more source