Results 221 to 230 of about 9,392,963 (368)

Patterns of cortical activity and memory performance in Alzheimer’s disease [PDF]

, 2001
Johannes Schröder, Monte S. Buchsbaum, Lina Shihabuddin, Cheuk Y. Tang, Tse-Chung Wei, Jacqueline Spiegel-Cohen, Erin A. Hazlett, L. ABEL, Christina Luu-Hsia, Tina M. Ciaravolo, Deborah B. Marin, Kenneth L. Davis   +11 more
openalex   +1 more source

Delivery of Molecular Hydrogen for Precision Immunomodulation: Mechanisms, Detection Methods, and Applications

Advanced Science, EarlyView.
This review focuses on the immunomodulatory mechanisms of molecular hydrogen, the recent detection methods, and the classification advanced molecular hydrogen delivery materials. It provides a detailed description of their applications in areas such as arthritis, chronic wounds, cardiovascular injury, tumors, and bacterial infections, aiming to enhance
Gangfeng Li, Hannan Cui, Ruixiao Fan, Guming Liu, Zishuo Hou, Yibo Zhang, Xuanming Che, Tengjiao Wang, Hongbo Wei, Peng Li   +9 more
wiley   +1 more source

Inhibition of Phosphodiesterase 10A by MP‐10 Rescues Behavioral Deficits and Normalizes Microglial Morphology and Synaptic Pruning in A Mouse Model of FOXP1 Syndrome

Advanced Science, EarlyView.
We demonstrate that Foxp1± mice, modeling FOXP1 haploinsufficiency, exhibit behavioral deficits, striatal neuroinflammatory changes including altered microglial complexity and synaptic pruning, and markedly reduced Pde10a expression. Pde10a inhibition starting immediately after birth restores Foxp1± behavior, microglial morphology, and pruning ...
Henning Fröhlich, Jing Wang, Ferdinand Althammer, Tim Schubert, Nina Kluck, Valery Grinevich, Stefanie Schmitteckert, Christian P. Schaaf, Gudrun A. Rappold   +8 more
wiley   +1 more source

Amyloid Angiopathy and Variability in Amyloid β Deposition Is Determined by Mutation Position in Presenilin-1-Linked Alzheimer’s Disease [PDF]

, 2001
David M. A. Mann, Stuart Pickering‐Brown, Ayano Takeuchi, Takeshi Iwatsubo   +3 more
openalex   +1 more source

Inflammation and Alzheimer’s disease

Neurobiology of Aging, 2000
H. Akiyama, S. Barger, S. Barnum, B. Bradt, J. Bauer, G. Cole, N. Cooper, P. Eikelenboom, M. Emmerling, B. Fiebich, C. Finch, S. Frautschy, W. Griffin, H. Hampel, M. Hull, G. Landreth, L. Lue, R. Mrak, I. Mackenzie, P. Mcgeer, M. O’Banion, J. Pachter, G. Pasinetti, C. Plata-salamán, J. Rogers, R. Rydel, Yong Shen, W. Streit, R. Strohmeyer, Ikuo Tooyoma, F. L. Muiswinkel, R. Veerhuis, D. Walker, S. Webster, Beatrice Wegrzyniak, G. Wenk, T. Wyss-Coray   +36 more
semanticscholar   +1 more source

Bacteroides Fragilis‐Derived Outer Membrane Vesicles Deliver MiR‐5119 and Alleviate Colitis by Targeting PD‐L1 to Inhibit GSDMD‐Mediated Neutrophil Extracellular Trap Formation

Advanced Science, EarlyView.
Bacteroides fragilis‐derived outer membrane vesicles deliver miR‐5119 and alleviate colitis by targeting PD‐L1 to inhibit GSDMD‐mediated neutrophil extracellular trap formation. Abstract Inflammatory bowel disease (IBD) results from a breakdown in the symbiotic relationship between the intestinal commensal microflora and the mucosal immune system.
Yi Yang, Lanmengxi Yang, Yilin Yang, Haiyi Deng, Shiyu Su, Yinxiao Xia, Jin Su, Yuheng Liu, Junwei Wu, Jing Zhang, Yao Liao, Lifu Wang   +11 more
wiley   +1 more source

The role of complement in Alzheimer’s disease pathology

, 2000
Mark R. Emmerling, M. Desiree Watson, C Raby, Katharyn Spiegel   +3 more
openalex   +1 more source

Brain Regional Quantification of F-Ring and D-/E-Ring Isoprostanes and Neuroprostanes in Alzheimer’s Disease [PDF]

, 2001
Erin E. Reich, William R. Markesbery, L. Jackson Roberts, Larry L. Swift, Jason D. Morrow, Thomas J. Montine   +5 more
openalex   +1 more source

Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine

Advanced Science, EarlyView.
Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang, Feng Gao, Liqun Yu, Haokun Chen, Rongrong Zhu   +4 more
wiley   +1 more source

Single-cell transcriptomic analysis of Alzheimer’s disease

Nature, 2019
Hansruedi Mathys, J. Dávila-Velderrain, Zhuyu Peng, Fan Gao, S. Mohammadi, Jennie Z. Young, M. Menon, Liang He, Fatema Abdurrob, Xueqiao Jiang, Anthony J. Martorell, R. Ransohoff, B. Hafler, D. Bennett, Manolis Kellis, L. Tsai   +15 more
semanticscholar   +1 more source