Results 111 to 120 of about 4,881,215 (246)
Advanced Science, EarlyView.Our study reveals the protective role of GPR124 in maintaining BBB integrity and promoting neurological recovery following TBI. It makes a significant contribution by uncovering a novel molecular interaction between GPR124 and FGFBP1 and linking this to activation of the Wnt/β‐catenin signaling pathway in vascular repair mechanisms.
Chen Wang +13 more
wiley +1 more source
IEEE AccessRecent research has revealed that using machine learning systems for the analysis of genetic data could reliably detect Alzheimer’s disease. The interpretability of these models, however, has been a challenge, as they frequently provided little ...
Tarek Khater +8 more
doaj +1 more source
Dementia Caregiving in Virginia: Data from the 2015 Behavioral Risk Factor Surveillance System
In Virginia, more than 60 percent of all adults providing unpaid care to loved ones with Alzheimer\u2019s or another dementia have been doing so for at least two years.This Fact Sheet is supported by Cooperative Agreement #NU58DP006115 from the Centers ...
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Pharmalogical developments and innovations for alzheimer disease
, 2021 the alzheimer disease is the most common dementia diseases worldwide. this neurodegenerative disease is a progressive disease which cause eventually a memory imperment, and as it progress also motor and functional disabilities. in my thesis i wrote about
Kronzilber, May
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Advanced Science, EarlyView.This study uncovers hierarchical coordination between K11 lactylation and S199 phosphorylation of CKB in cerebral ischemia‐reperfusion injury. Such dual modifications potentiate CKB enzymatic function, remodel energy metabolism, alleviate oxidative stress and neuronal damage, and represent a viable therapeutic target for stroke treatment.
Chao Duan +17 more
wiley +1 more source
Dental Research Journal, 2014 Background: Despite the outbreak in dental science, oral and dental complications in Alzheimer are of the unsolved problems. It is assumed that tumor necrosis factor-α, which is a key factor in Alzheimer, has a relation with periodontal complications in ...
Shirin Zahra Farhad +6 more
doaj
Dementia Caregiving in Indiana: Data from the 2015 Behavioral Risk Factor Surveillance System
In Indiana, more than 60 percent of all adults providing unpaid care to loved ones with Alzheimer\u2019s or another dementia have been doing so for at least two years.This Fact Sheet is supported by Cooperative Agreement #NU58DP006115 from the Centers ...
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Modulation of miR‐23b Wnt/β‐catenin Axis Strengthens Endothelial Barrier Properties
Advanced Science, EarlyView.Early blood‐brain barrier (BBB) disruption contributes to stroke and CNS disease pathology. miR‐23b was identified as a regulator of BBB integrity in brain endothelial cells. Inhibition of miR‐23b enhanced barrier‐associated properties, promoted repair‐related signaling, and reduced BBB leakage in experimental stroke models, supporting further ...
Victor Anthony Martinez +16 more
wiley +1 more source
Dementia caregiving in Arizona: Data from the 2016 Behavioral Risk Factor Surveillance System
In Arizona, more than half of all adults providing unpaid care to loved ones with Alzheimer\u2019s or another dementia have been doing so for at least two years.This Fact Sheet is supported by Cooperative Agreement #NU58DP006115 from the Centers for ...
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