Brazilian Journal of Medical and Biological Research, 2006 To quantify the effects of methylmercury (MeHg) on amacrine and on ON-bipolar cells in the retina, experiments were performed in MeHg-exposed groups of adult trahiras (Hoplias malabaricus) at two dose levels (2 and 6 µg/g, ip).
D.M.O. Bonci +5 more
doaj +1 more source
Thyroid Hormone Signaling in the Mouse Retina. [PDF]
PLoS ONE, 2016 Thyroid hormone is a crucial regulator of gene expression in the developing and adult retina. Here we sought to map sites of thyroid hormone signaling at the cellular level using the transgenic FINDT3 reporter mouse model in which neurons express β ...
Patrick Arbogast +4 more
doaj +1 more source
Frontiers in Neuroscience, 2023 Sequence variants modulating gene function or expression affect various heritable traits, including the number of neurons within a population. The present study employed a forward-genetic approach to identify candidate causal genes and their sequence ...
Bridget Kulesh +11 more
doaj +1 more source
An Amacrine Cell Circuit for Signaling Steady Illumination in the Retina
Cell Reports, 2015 Decades of research have focused on the circuit connectivity between retinal neurons, but only a handful of amacrine cells have been described functionally and placed in the context of a specific retinal circuit.
Jason Jacoby +3 more
doaj +1 more source
Decellularised extracellular matrix-derived peptides from neural retina and retinal pigment epithelium enhance the expression of synaptic markers and light responsiveness of human pluripotent stem cell derived retinal organoids [PDF]
, 2019 Tissue specific extracellular matrices (ECM) provide structural support and enable access to molecular signals and metabolites, which are essential for directing stem cell renewal and differentiation.
Al-Aama, Jumana +15 more
core +2 more sources
Ih channels control feedback regulation from amacrine cells to photoreceptors. [PDF]
PLoS Biology, 2015 In both vertebrates and invertebrates, photoreceptors' output is regulated by feedback signals from interneurons that contribute to several important visual functions.
Wen Hu +3 more
doaj +1 more source
Inhibitory control of feature selectivity in an object motion sensitive circuit of the retina [PDF]
, 2017 Object motion sensitive (OMS) W3-retinal ganglion cells (W3-RGCs) in mice respond to local movements in a visual scene but remain silent during self-generated global image motion. The excitatory inputs that drive responses of W3-RGCs to local motion were
Kerschensteiner, Daniel, Kim, Tahnbee
core +3 more sources
Frontiers in Molecular Neuroscience, 2019 In the mammalian retina, amacrine cells represent the most diverse cell class and are involved in the spatio-temporal processing of visual signals in the inner plexiform layer.
Shubhash C. Yadav +3 more
doaj +1 more source
Dendritic and axonal targeting patterns of a genetically-specified class of retinal ganglion cells that participate in image-forming circuits. [PDF]
, 2014 BackgroundThere are numerous functional types of retinal ganglion cells (RGCs), each participating in circuits that encode a specific aspect of the visual scene.
Feldheim, David A +6 more
core +2 more sources
Docosahexaenoic acid promotes photoreceptor differentiation without altering Crx expression [PDF]
, 2006 PURPOSE: The precise molecular cues required for photoreceptor development are still unknown. Pax6 and Crx are essential during early retinal development and for photoreceptor differentiation, respectively.
Garelli, Andres +2 more
core +2 more sources