Results 41 to 50 of about 26,228 (200)
Monocyte-macrophage differentiation of acute myeloid leukemia cell lines by small molecules identified through interrogation of the Connectivity Map database [PDF]
, 2015 The transcription factor C/EBPα is required for granulocytic differentiation of normal myeloid progenitors and is frequently inactivated in acute myeloid leukemia (AML) cells. Ectopic expression of C/EBPα in AML cells suppresses proliferation and induces
CALABRETTA, Bruno +9 more
core +1 more source
Effects of TENS and methylphenidate in tuberculous meningo-encephalistis [PDF]
, 2001 Primary objective: Beneficial effects of transcutaneous electrical nerve stimulation (TENS) on cognition and behaviour were observed in a child with probable Herpes Simplex Encephalitis.
Ferenschild, K.C.M.P. +5 more
core +1 more source
Rupture Test and Bioavailability of Oil-Soluble Vitamins [PDF]
, 2013 In lieu of an abstract, here is the article\u27s first paragraph: Bioavailability of multi-vitamins as dietary supplements has always been a concern. Dissolution studies have been successfully used to predict drug release of bioactive molecules, but with
Chablani, Lipika
core +2 more sources
Amantadine toxic effect and acute psychosis – a case report
Journal of Education, Health and Sport, 2023 Introduction and purpose: The pandemic of COVID-19 has induced patients to use different ways to struggle with SARS-CoV-2 infection. Amantadine has become more popular as a supportive drug in the treatment of COVID-19 symptoms.
Dariusz Gruca +3 more
doaj +1 more source
Influenza virus strains with a fusion threshold of pH 5.5 or lower are inhibited by amantadine. Brief report [PDF]
, 1986 Nineteen influenza virus strains were examined for susceptibility to amantadine-HCl (AMT) and for pH-thresholds of haemagglutinin-induced haemolysis. Whereas pH-thresholds below 5.5 were not seen in AMT-resistant strains, AMT-sensitive strains showed pH ...
Beyer, W.E.Ph. (Walter) +3 more
core +2 more sources
Network Localization of Fatigue in Multiple Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo +12 more
wiley +1 more source
Sleep Science, 2023 Objective Amantadine has both anti-glutamatergic and dopaminergic action and may improve restless legs syndrome (RLS). We compared the efficacy and adverse-effect profile of amantadine and ropinirole in RLS.
Govind Madhaw +3 more
doaj +1 more source
Use of Symptomatic Drug Treatment for Fatigue in Multiple Sclerosis and Patterns of Work Loss
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To describe the use of central stimulants and amantadine for fatigue in MS and evaluate a potential association with reduced work loss in people with MS. Methods We conducted a nationwide, matched, register‐based cohort study in Sweden (2006 to 2023) using national registers with prospective data collection.
Simon Englund +3 more
wiley +1 more source
Untargeted metabolomics reveals the mechanism of amantadine toxicity on Laminaria japonica
Frontiers in PhysiologyThe antiviral agent amantadine is frequently detected in seawater and marine organisms. Because of increasing concentrations, amantadine has become a contaminant of emerging concern.
Xiaohan Wang +6 more
doaj +1 more source
Case Reports in Neurological Medicine, 2022 Introduction. Several reports have described the use of amantadine for managing symptoms in Marchiafava–Bignami disease (MBD); however, amantadine’s role for the treatment of MBD symptoms is unclear. Here, we describe 2 patients with MBD who were treated
Leenil Noel +2 more
doaj +1 more source