Results 21 to 30 of about 13,942 (180)

The Effectiveness of Amantadine in Improving Consciousness in Patients with Acute Brain Injury

open access: yesArchives of Anesthesia and Critical Care, 2023
Background: The improved consciousness level reflects the patient’s recovery following acute brain injury. The medications that can regulate neurotransmitter levels, neural synaptic plasticity, and functional connectivity of consciousness networks might
Alireza Rahat Dahmardeh   +3 more
doaj   +1 more source

Theoretical Investigation of Amantadine Adsorption on Sc-, Ti-, and Zn-Boron Nitride Nanosheets: DFT, NBO, and QTAIM [PDF]

open access: yesNanochemistry Research, 2023
In this work, the potentials of Sc-, Ti-, and Zn-doped BN nanosheets for adsorbing and detecting the amantadine drug were studied by using density functional theory (DFT), natural bond orbital (NBO), and quantum theory of atoms in molecules (QTAIM).
Ebrahim Saedi khosroshahi   +4 more
doaj   +1 more source

A Case Report of Severe Delirium after Amantadine Withdrawal

open access: yesCase Reports in Neurology, 2017
Amantadine is frequently used in addition to dopaminergic substances like dopamine agonists or L-Dopa in advanced Parkinson disease (PD). However, adverse effects like hallucinations limit its use.
Franz Marxreiter   +3 more
doaj   +1 more source

Potential antidepressant effect of amantadine: a review of preclinical studies and clinical trials

open access: yesBrazilian Journal of Psychiatry, 2018
Objective: Amantadine blocks N-methyl-D-aspartate (NMDA) receptors and has dopaminergic and noradrenergic action, a neurochemical profile that suggests its potential as an antidepressant drug.
Inara F. Raupp-Barcaro   +3 more
doaj   +1 more source

Associations Between Amantadine Usage, Gait, and Cognition in PSP: A post-hoc Analysis of the Davunetide Trial

open access: yesFrontiers in Neurology, 2020
Introduction: Amantadine anecdotally improves gait in progressive supranuclear palsy (PSP) but definitive data is lacking. We investigated associations between amantadine usage, gait, cognition, and activities of daily living in 310 subjects with PSP ...
Marian L. Dale   +3 more
doaj   +1 more source

The Structural Characteristics of Compounds Interacting with the Amantadine-Sensitive Drug Transport System at the Inner Blood–Retinal Barrier

open access: yesPharmaceuticals, 2023
Blood-to-retina transport across the inner blood–retinal barrier (BRB) is a key determinant of retinal drug concentration and pharmacological effect. Recently, we reported on the amantadine-sensitive drug transport system, which is different from well ...
Yusuke Shinozaki   +3 more
doaj   +1 more source

Amantadine can induce intra-epithelial deposition in the cornea

open access: yesAmerican Journal of Ophthalmology Case Reports, 2020
Purpose: Amantadine has been reported to cause various corneal complications, such as superficial punctate keratitis, corneal endothelial dysfunction, and corneal edema.
Asayo Yoshinaka   +2 more
doaj   +1 more source

Preliminary Study of Intravenous Amantadine Treatment for Ataxia Management in Patients with Probable Multiple System Atrophy with Predominant Cerebellar Ataxia [PDF]

open access: yesJournal of Movement Disorders, 2012
Background and Purpose: Multiple system atrophy with predominant cerebellar ataxia is a disabling neurologic disease. However, effective management has not yet been established.
Jinyoung Youn   +3 more
doaj   +1 more source

Right ventricular outflow tract tachycardia after an initial dose of amantadine

open access: yesTürk Kardiyoloji Derneği Arşivi, 2015
Amantadine hydrochloride is an antiviral agent that is also effective in the treatment of Parkinson's disease. In the literature, cardiac arrhythmia is reported in toxic doses of amantadine, but in this paper we report a patient with right ventricular ...
Cüneyt Kocaş   +3 more
doaj   +1 more source

Amantadine Continuation After Hospital Discharge for Acute Stroke Requiring Inpatient Rehabilitation: A Long-term Follow-up Study

open access: yesArchives of Rehabilitation Research and Clinical Translation
Objectives: To describe the dosing strategy, safety, and effectiveness of amantadine in patients admitted to inpatient rehabilitation after stroke. Design: Retrospective, single-center, cohort study. Setting: Ninety-bed, inpatient rehabilitation hospital.
Haley R. Torr, PharmD   +9 more
doaj   +1 more source

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