Results 21 to 30 of about 18,186 (211)

Directional Deep Brain Stimulation for Parkinson's Disease: Results of an International Crossover Study With Randomized, Double‐Blind Primary Endpoint

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objective Published reports on directional deep brain stimulation (DBS) have been limited to small, single‐center investigations. Therapeutic window (TW) is used to describe the range of stimulation amplitudes achieving symptom relief without side effects.
Alfons Schnitzler, Pablo Mir, Matthew A. Brodsky, Leonard Verhagen, Sergiu Groppa, Ramiro Alvarez, Andrew Evans, Marta Blazquez, Sean Nagel, Julie G. Pilitsis, Monika Pötter‐Nerger, Winona Tse, Leonardo Almeida, Nestor Tomycz, Joohi Jimenez‐Shahed, Witold Libionka, Fatima Carrillo, Christian J. Hartmann, Stefan Jun Groiss, Martin Glaser, Florence Defresne, Edward Karst, Binith Cheeran, Jan Vesper, for the PROGRESS Study Investigators   +24 more
wiley   +1 more source

A semi-quantitative multi-range lateral flow immunoassay for amantadine residues in livestock and poultry products

Food and Agricultural Immunology, 2022
Amantadine is one of the most prescribed antiviral medications. Considering its abuse is life-threatening, monitoring amantadine residues is urgently needed.
Xiangxue Ning, Jing Qiu
doaj   +1 more source

Early amantadine treatment reduces the risk of death in patients with large hemisphere infarctions:a Chinese hospital-based study

BMC Neurology, 2021
Background Amantadine hydrochloride is one of the most frequently prescribed drugs for patients with severe traumatic brain injury in restoring consciousness and accelerating the pace of functional recovery.
Jie Li, Ping Zhang, Yingying Liu, Simiao Wu, Xingyang Yi, Shihong Zhang, Chun Wang, Ming Liu   +7 more
doaj   +1 more source

Amantadine-induced keratopathy

Indian Journal of Ophthalmology. Case Reports, 2023
Amantadine-induced corneal epithelial disease has been reported less frequently than corneal edema. We report an elderly patient with Parkinson's disease who developed superficial punctate keratitis, corneal epithelial hypertrophy, and visual disturbance
Nehal Mohata, Samrat Chatterjee, Sharad N Gomase, Deepshikha Agrawal   +3 more
doaj   +1 more source

Bioavailability and Pharmacokinetics of Once-Daily Amantadine Extended-Release Tablets in Healthy Volunteers: Results from Three Randomized, Crossover, Open-Label, Phase 1 Studies

Neurology and Therapy, 2019
Introduction In February 2018, OS320—an amantadine extended-release (ER) tablet formulation with once-daily morning administration—was approved for the treatment of Parkinson’s disease and drug-induced extrapyramidal reactions in adults.
Tina deVries, Angela Dentiste, Lata Handiwala, David Jacobs   +3 more
doaj   +1 more source

Transcranial direct current stimulation combined with amantadine in repetitive mild traumatic brain injury in rats

BMC Neuroscience, 2022
Background Balance and memory deficits are common in patients with repetitive mild traumatic brain injury (mTBI). Objective To investigate the combined effects of amantadine and transcranial direct current stimulation (tDCS) on balance and memory in ...
Soo Jeong Han, Gahee Park, Jee Hyun Suh
doaj   +1 more source

The sequence analysis of M2 gene for identification of amantadine resistance in avian influenza virus (H9N2 subtype), detected from broiler chickens with respiratory syndrome during 2016-2018, in Isfahan-Iran

Acta Scientiarum: Animal Sciences, 2022
vAmantadine and rimantadine are used for prevention and treatment of influenza A virus (IAV) infection. The rates of resistant IAVs have been increasing globally.
Majid Gholami-Ahangaran, Asal Basiratpour, Oveys Pourmahdi, Pedram Khorrami, Mehrdad Ostadpoor, Mohammad Javad Mirbagheri, Asiye Ahmadi-Dastgerdi   +6 more
doaj   +1 more source

Amantadine for dyskinesias in Parkinson's disease: a randomized controlled trial. [PDF]

, 2010
BACKGROUND: Dyskinesias are some of the major motor complications that impair quality of life for patients with Parkinson's disease. The purpose of the present study was to investigate the efficacy of amantadine in Parkinson's disease patients suffering ...
Oeda Tomoko, Hisanaga Kinya, Tomoko Oeda, Mitsutoshi Yamamoto, Yamamoto Kenji, Kenji Yamamoto, Sawada Hideyuki, Takashi Kawamura, Sadako Kuno, Kuno Sadako, Yamamoto Mitsutoshi, Hideyuki Sawada, null null, Kinya Hisanaga, Masahiro Nomoto, Kawamura Takashi, Nomoto Masahiro, Amantadine Study Group   +17 more
core   +1 more source

The Structural Characteristics of Compounds Interacting with the Amantadine-Sensitive Drug Transport System at the Inner Blood–Retinal Barrier

Pharmaceuticals, 2023
Blood-to-retina transport across the inner blood–retinal barrier (BRB) is a key determinant of retinal drug concentration and pharmacological effect. Recently, we reported on the amantadine-sensitive drug transport system, which is different from well ...
Yusuke Shinozaki, Yuma Tega, Shin-ichi Akanuma, Ken-ichi Hosoya   +3 more
doaj   +1 more source

The Effectiveness of Amantadine in Improving Consciousness in Patients with Acute Brain Injury

Archives of Anesthesia and Critical Care, 2023
Background: The improved consciousness level reflects the patient’s recovery following acute brain injury. The medications that can regulate neurotransmitter levels, neural synaptic plasticity, and functional connectivity of consciousness networks might
Alireza Rahat Dahmardeh, Aliakbar Keykha, Mehdi Rezvani Amin, Masoum Khoshfetrat   +3 more
doaj   +1 more source