Results 11 to 20 of about 13,942 (180)

The importance of longitudinal evaluation using DAT-SPECT in organophosphate-induced toxic parkinsonism. [PDF]

PCN Rep
We performed longitudinal evaluation using magnetic resonance imaging (MRI) and dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) in a case of organophosphate‐induced toxic parkinsonism. Fluid‐attenuated inversion recovery (FLAIR) images showed bilateral striatal hyperintensity in the acute phase, followed by reduction of ...
Nakao S, Kogoh Y, Funahashi H, Yanoma Y, Azuma M, Ishida Y, Hirano Y.   +6 more
europepmc   +2 more sources

Intravenous amantadine for freezing of gait resistant to dopaminergic therapy: a randomized, double-blind, placebo-controlled, cross-over clinical trial. [PDF]

PLoS ONE, 2012
Freezing of gait (FOG) is one of the most disabling symptoms in Parkinsonism. Open-label studies have suggested that intravenous (IV) amantadine is effective against FOG resistant to dopaminergic therapy in Parkinson's disease (PD).
Young Eun Kim, Ji Young Yun, Hui June Yang, Han-Joon Kim, Namyi Gu, Seo Hyun Yoon, Joo-Youn Cho, Beom S Jeon   +7 more
doaj   +1 more source

A semi-quantitative multi-range lateral flow immunoassay for amantadine residues in livestock and poultry products

Food and Agricultural Immunology, 2022
Amantadine is one of the most prescribed antiviral medications. Considering its abuse is life-threatening, monitoring amantadine residues is urgently needed.
Xiangxue Ning, Jing Qiu
doaj   +1 more source

Early amantadine treatment reduces the risk of death in patients with large hemisphere infarctions:a Chinese hospital-based study

BMC Neurology, 2021
Background Amantadine hydrochloride is one of the most frequently prescribed drugs for patients with severe traumatic brain injury in restoring consciousness and accelerating the pace of functional recovery.
Jie Li, Ping Zhang, Yingying Liu, Simiao Wu, Xingyang Yi, Shihong Zhang, Chun Wang, Ming Liu   +7 more
doaj   +1 more source

Amantadine-induced keratopathy

Indian Journal of Ophthalmology. Case Reports, 2023
Amantadine-induced corneal epithelial disease has been reported less frequently than corneal edema. We report an elderly patient with Parkinson's disease who developed superficial punctate keratitis, corneal epithelial hypertrophy, and visual disturbance
Nehal Mohata, Samrat Chatterjee, Sharad N Gomase, Deepshikha Agrawal   +3 more
doaj   +1 more source

Amantadine-induced corneal edema: A case and literature review

American Journal of Ophthalmology Case Reports, 2023
Purpose: To present a case of irreversible corneal edema after 10 years of amantadine use. A literature review was carried out to describe the clinical characteristics and outcomes of amantadine-induced corneal edema.
Antony Raharja, Wessam Mina, Zahra Ashena   +2 more
doaj   +1 more source

Transcranial direct current stimulation combined with amantadine in repetitive mild traumatic brain injury in rats

BMC Neuroscience, 2022
Background Balance and memory deficits are common in patients with repetitive mild traumatic brain injury (mTBI). Objective To investigate the combined effects of amantadine and transcranial direct current stimulation (tDCS) on balance and memory in ...
Soo Jeong Han, Gahee Park, Jee Hyun Suh
doaj   +1 more source

Amantadine variant – aryl conjugates that inhibit multiple M2 mutant – amantadine resistant influenza a viruses

European Journal of Medicinal Chemistry Reports, 2022
Influenza A viruses can cause a serious future threat due to frequent mutations. Amantadine and rimantadine drugs inhibit influenza A M2 wild-type (WT; bearing in the protein M2 proton channel serine at position-31) viruses by binding and blocking M2 WT ...
Christina Tzitzoglaki, Anja Hoffmann, Andreea L. Turcu, Patrick Schmerer, Chunlong Ma, George Laros, Christos Liolios, Brea José, Jun Wang, Santiago Vázquez, Michaela Schmidtke, Antonios Kolocouris   +11 more
doaj   +1 more source

Directional Deep Brain Stimulation for Parkinson's Disease: Results of an International Crossover Study With Randomized, Double‐Blind Primary Endpoint

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objective Published reports on directional deep brain stimulation (DBS) have been limited to small, single‐center investigations. Therapeutic window (TW) is used to describe the range of stimulation amplitudes achieving symptom relief without side effects.
Alfons Schnitzler, Pablo Mir, Matthew A. Brodsky, Leonard Verhagen, Sergiu Groppa, Ramiro Alvarez, Andrew Evans, Marta Blazquez, Sean Nagel, Julie G. Pilitsis, Monika Pötter‐Nerger, Winona Tse, Leonardo Almeida, Nestor Tomycz, Joohi Jimenez‐Shahed, Witold Libionka, Fatima Carrillo, Christian J. Hartmann, Stefan Jun Groiss, Martin Glaser, Florence Defresne, Edward Karst, Binith Cheeran, Jan Vesper, for the PROGRESS Study Investigators   +24 more
wiley   +1 more source

The sequence analysis of M2 gene for identification of amantadine resistance in avian influenza virus (H9N2 subtype), detected from broiler chickens with respiratory syndrome during 2016-2018, in Isfahan-Iran

Acta Scientiarum: Animal Sciences, 2022
vAmantadine and rimantadine are used for prevention and treatment of influenza A virus (IAV) infection. The rates of resistant IAVs have been increasing globally.
Majid Gholami-Ahangaran, Asal Basiratpour, Oveys Pourmahdi, Pedram Khorrami, Mehrdad Ostadpoor, Mohammad Javad Mirbagheri, Asiye Ahmadi-Dastgerdi   +6 more
doaj   +1 more source