Results 31 to 40 of about 18,186 (211)

Potential antidepressant effect of amantadine: a review of preclinical studies and clinical trials

open access: yesBrazilian Journal of Psychiatry, 2018
Objective: Amantadine blocks N-methyl-D-aspartate (NMDA) receptors and has dopaminergic and noradrenergic action, a neurochemical profile that suggests its potential as an antidepressant drug.
Inara F. Raupp-Barcaro   +3 more
doaj   +1 more source

Theoretical Investigation of Amantadine Adsorption on Sc-, Ti-, and Zn-Boron Nitride Nanosheets: DFT, NBO, and QTAIM [PDF]

open access: yesNanochemistry Research, 2023
In this work, the potentials of Sc-, Ti-, and Zn-doped BN nanosheets for adsorbing and detecting the amantadine drug were studied by using density functional theory (DFT), natural bond orbital (NBO), and quantum theory of atoms in molecules (QTAIM).
Ebrahim Saedi khosroshahi   +4 more
doaj   +1 more source

Associations Between Amantadine Usage, Gait, and Cognition in PSP: A post-hoc Analysis of the Davunetide Trial

open access: yesFrontiers in Neurology, 2020
Introduction: Amantadine anecdotally improves gait in progressive supranuclear palsy (PSP) but definitive data is lacking. We investigated associations between amantadine usage, gait, cognition, and activities of daily living in 310 subjects with PSP ...
Marian L. Dale   +3 more
doaj   +1 more source

Preliminary Study of Intravenous Amantadine Treatment for Ataxia Management in Patients with Probable Multiple System Atrophy with Predominant Cerebellar Ataxia [PDF]

open access: yesJournal of Movement Disorders, 2012
Background and Purpose: Multiple system atrophy with predominant cerebellar ataxia is a disabling neurologic disease. However, effective management has not yet been established.
Jinyoung Youn   +3 more
doaj   +1 more source

Amantadine Revisited: A Contender for Initial Treatment in Parkinson’s Disease?

open access: yes, 2021
The best practice for the initiation of symptomatic motor treatment for Parkinson’s disease is an ongoing topic of debate. Fueled by interpretation of the results of the LEAP and MED Parkinson’s disease studies, many practitioners opt for early ...
Marmol, Sarah   +7 more
core   +1 more source

A Randomized, Open Label, Exploratory Trial Comparing Efficacy of Amantadine and Ropinirole in Restless Legs Syndrome

open access: yes, 2023
Objective Amantadine has both anti-glutamatergic and dopaminergic action and may improve restless legs syndrome (RLS).
Puneet Dhamija   +3 more
core   +1 more source

Amantadine Continuation After Hospital Discharge for Acute Stroke Requiring Inpatient Rehabilitation: A Long-term Follow-up Study

open access: yesArchives of Rehabilitation Research and Clinical Translation
Objectives: To describe the dosing strategy, safety, and effectiveness of amantadine in patients admitted to inpatient rehabilitation after stroke. Design: Retrospective, single-center, cohort study. Setting: Ninety-bed, inpatient rehabilitation hospital.
Haley R. Torr, PharmD   +9 more
doaj   +1 more source

Amantadine-induced peripheral neuropathy

open access: yes, 1999
We report a 48-year-old woman with a 17-year history of PD who developed a peripheral sensory-motor neuropathy secondary to chronic administration (8 years) of amantadine.
Minagar, A   +3 more
core   +1 more source

Amantadine for the treatment of childhood and adolescent psychiatric symptoms [PDF]

open access: yes, 2021
This retrospective study examined clinical parameters associated with amantadine treatment of psychiatric symptoms in children. A total of 297 pediatric patients were prescribed amantadine and met study criteria to assess clinical responses and ...
Boduch, Cassandra   +11 more
core   +1 more source

Supramolecular Allostery Achieves Tunable Luminescence Aromatic Bridged Phenothiazine Noncovalent Frameworks

open access: yesAdvanced Science, EarlyView.
Tunable luminescent supramolecular organic framework enabled by multiple allosteric effects, composed of a tetracation vinylphenylpyridinium‐modified aromatic‐bridged phenothiazine guest and cucurbit[8]uril, not only exhibits unique guest oxidation‐driven NIR luminescence blue‐shift and effectively enhances the quantum yield by 46‐fold to 22.2% but ...
Xinping Lu, Jianchong Chen, Jie Yu
wiley   +1 more source

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