Results 41 to 50 of about 13,942 (180)

The Effect of Systemic Amantadine Sulfate on Malondialdehyde and Total Thiol Levels in Rat Corneas

Journal of Ophthalmic & Vision Research, 2014
Purpose: To evaluate the malondialdehyde (MDA) and total thiol (sulfhydryl, SH) levels in rat corneas after intraperitoneal injection of amantadine sulfate.
Züleyha Yalniz-Akkaya, Vildan Fidanci, Aytul Kilinc, Ayse Burcu, Guner O Uney, Firdevs Ornek   +5 more
doaj   +1 more source

Inhibitory effects on HAV IRES-mediated translation and replication by a combination of amantadine and interferon-alpha

Virology Journal, 2010
Hepatitis A virus (HAV) causes acute hepatitis and sometimes leads to fulminant hepatitis. Amantadine is a tricyclic symmetric amine that inhibits the replication of many DNA and RNA viruses.
Yang Lingli, Kiyohara Tomoko, Kanda Tatsuo, Imazeki Fumio, Fujiwara Keiichi, Gauss-Müller Verena, Ishii Koji, Wakita Takaji, Yokosuka Osamu   +8 more
doaj   +1 more source

Low dose Amantadine and Escitalopram combination in Atypical Parkinsonian disorders- A Retrospective chart review

European Psychiatry, 2023
Introduction The response to conventional antiparkinsonian medications is elusive in atypical parkinsonian disorders. Improvement in parkinsonian symptoms in atypical parkinsonian disorders has been reported with anecdotal use of Amantadine. The role of
S. M. Tripathi, P. Chutia
doaj   +1 more source

Resolution of Levodopa/Dopa‐Decarboxylase Inhibitor—Associated Microscopic Colitis with Subcutaneous Foslevodopa/Foscarbidopa: A Case Series and Review of the Literature

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Microscopic colitis (MC) typically presents with chronic, non‐bloody watery diarrhea. Diagnosis requires endoscopy with colonic mucosal biopsies. The etiology is multifactorial, with several medications implicated, although only a few cases have been attributed to oral levodopa/dopa‐decarboxylase inhibitor (LDDCI) therapy.
Romana Hintner, Franziska Eberhardt, Manuela Kofler, Andreas Eigentler, Atbin Djamshidian, Florian Krismer, Anton Hittmair, Heinz Zoller, Valentina Ellinger, Beatrice Heim, Klaus Seppi   +10 more
wiley   +1 more source

A Randomized, Open Label, Exploratory Trial Comparing Efficacy of Amantadine and Ropinirole in Restless Legs Syndrome

Sleep Science, 2023
Objective Amantadine has both anti-glutamatergic and dopaminergic action and may improve restless legs syndrome (RLS). We compared the efficacy and adverse-effect profile of amantadine and ropinirole in RLS.
Govind Madhaw, Ravi Gupta, Puneet Dhamija, Niraj Kumar   +3 more
doaj   +1 more source

Informing future randomized controlled trials of amantadine hydrochloride in neurocritical care and post-neurocritical care stroke patients through a retrospective study

BMC Neurology
Background Amantadine hydrochloride has been increasingly prescribed as a neurostimulant for neurocritical care stroke patients to promote wakefulness during inpatient recovery.
Enzo G. Plaitano, Rebecca A. Scharf, Pakinam E. Aboutaleb, Andrea L. Glennon, Emiliya Melkumova, Deborah M. Green-LaRoche   +5 more
doaj   +1 more source

Exocrine Gland Dysfunction in Parkinson's Disease: Pathophysiology, Clinical Manifestations, and Therapeutic Perspectives—A Narrative Review

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Non‐motor symptoms, especially autonomic dysfunction, are major contributors to disability and decreased quality of life in Parkinson's disease (PD). Despite being common and having a wide range of clinical facets, exocrine gland dysfunction is still not well recognized and managed.
Renato P. Munhoz, Marina Farah, Laura Silveira‐Moriyama   +2 more
wiley   +1 more source

Molecular docking investigation of the amantadine binding to the enzymes upregulated or downregulated in Parkinson’s disease

ADMET and DMPK, 2020
Parkinson’s disease (PD) is a progressive neurodegenerative disease. Levodopa in combination with amantadine has a demonstrated efficacy in motility impairment. An extensive investigation of some enzymes described to be upregulated or downregulated in PD
Mihaela Ileana Ionescu
doaj   +1 more source

Movement Disorders in Developmental and Epileptic Encephalopathies

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Monogenic developmental and epileptic encephalopathies (DEE) frequently feature co‐occurring movement disorders. Gene discovery has expanded epilepsy‐dyskinesia syndromes (EDS) from classic associations such as stereotypies in Rett syndrome to PRRT2‐related infantile seizures with paroxysmal dyskinesia and crouched gait in SCN1A ...
Shekeeb Mohammad, Darius Ebrahimi‐Fakhari, Hugo Morales‐Briceno   +2 more
wiley   +1 more source

Adamantine Amantadine

Journal of General Internal Medicine
Abstract Recognition of the serendipitous history of amantadine, first as a flu treatment and now as a Parkinson disease drug, and its adamantine persistence, and how small changes, like rearranging a few letters in a word or a DNA strand, can have a big impact.
openaire   +2 more sources