Results 31 to 40 of about 14,484 (237)

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Ambience: An Introduction [PDF]

, 2021
With this issue of Moveable Type, we hope to set in motion a new wave of interest in ambient literature, seeking new insight into the patterns and thematics of ambient writing and bringing to light discussions left unresolved by various critiques of ...
Fleming, W, Helmers, M, Edwards, S, Chambré, S   +3 more
core   +1 more source

RobôFrango: Proof of concept of a mobile biosensor robot for environmental monitoring in broiler houses

Results in Engineering
The use of mobile sensors represents an innovative strategy for monitoring environmental variables in broiler houses, enabling the identification of conditions that directly affect animal welfare.
Glauber da Rocha Balthazar, Robson Mateus Freitas Silveira, Thauane Cordeiro Soares, Iran José Oliveira da Silva   +3 more
doaj   +1 more source

Sistema silvipastoril na Amazônia: ferramenta para elevar o desempenho produtivo de búfalos Silvopastoral system in the Amazon region: tool to increase the productive performance of buffaloes

Ciência Rural, 2008
Os sistemas agroflorestais são arranjos de técnicas alternativas de uso de solo, combinando espécies florestais, culturas agrícolas e atividades pecuárias.
Anderson Corrêa Castro, José de Brito Lourenço Júnior, Núbia de Fátima Alves dos Santos, Edwana Mara Moreira Monteiro, Márcia Alessandra Brito de Aviz, Alexandre Rossetto Garcia   +5 more
doaj   +1 more source

ACOUSTIC ENVIRONMENT AND GAS PRODUCTION IN DIFFERENT GROWING-FINISHING SWINE FACILITIES [PDF]

Engenharia Agrícola, 2016
This study aimed to evaluate gas levels and the acoustic environment (noise) of growing-finishing swine in different facilities, one composed of shallow pool (SP) and another of partially slatted floor (PSF).
Rafaella R. Andrade, Alessandro T. Campos, Daiane Cecchin, Francine A. Sousa, Pedro I. S. Amaral   +4 more
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Development and validation of a rapid-prototyping IoT-based sensor system for poultry house microclimate monitoring

Smart Agricultural Technology
The industrial production system for broiler chickens involves raising the animals in an artificial environment (aviary) that must provide all necessary conditions to generate a suitable microclimate.
Glauber da Rocha Balthazar, Robson Mateus Freitas Silveira, José Tadeu Aldrigue, Iran José Oliveira da Silva   +3 more
doaj   +1 more source