Results 41 to 50 of about 4,183 (267)

ACOUSTIC ENVIRONMENT AND GAS PRODUCTION IN DIFFERENT GROWING-FINISHING SWINE FACILITIES [PDF]

Engenharia Agrícola, 2016
This study aimed to evaluate gas levels and the acoustic environment (noise) of growing-finishing swine in different facilities, one composed of shallow pool (SP) and another of partially slatted floor (PSF).
Rafaella R. Andrade, Alessandro T. Campos, Daiane Cecchin, Francine A. Sousa, Pedro I. S. Amaral   +4 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

CUSTOMER SATISFACTION TOWARDS THE PERCEPTION IN AMBIENCE OF SMALL CAR WITH REFERENCE TO MADURAI REGION [PDF]

ICTACT Journal on Management Studies, 2020
Some of the consumers who get satisfied in the ambience of the product, not bothering about the quality, utility, price and technology even never bother about their affordability.
N Selvaraj
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Análise espacial das condições térmicas do ambiente pré-ordenha de bovinos leiteiros sob regimes de climatização Spatial analysis of thermal conditions of the pre-milking dairy cattle under climatization regimes

Revista Brasileira de Engenharia Agrícola e Ambiental, 2012
Propõe-se, com este trabalho, caracterizar a variabilidade espacial da temperatura do ar na sala de pré-ordenha a partir de diferentes tempos de operação do sistema de resfriamento adiabático evaporativo automatizado.
Irenilson M. da Silva, Heliton Pandorfi, Gledson L. P. de Almeida, Cristiane Guiselini, Anildo M. Caldas, Arthur L. Jacob   +5 more
doaj   +1 more source

Un silence sans ambiance. Hammershøi, les impressionnistes et le tournant atmosphérique contemporain

Ambiances, 2023
This article aims at problematizing, from an aesthetic perspective, the contemporary “atmospheric turn”. From a confrontation between French impressionist painting and the painting of the Danish Vilhelm Hammershøi (1864-1916), we thus distinguish three ...
Hugues Choplin
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Influence of Retail Atmospherics as Nonverbal Communication on Purchase Behaviour in the Nigerian Retail Environment

Journal of Marketing and Consumer Behaviour in Emerging Markets, 2017
This paper focuses on unravelling the impact of atmospherics on shopper purchase behaviour in emerging markets like Nigeria and attempts to isolate the atmospheric cue that is the most signifi cant predictor of shopper purchase decisions. The paper seeks
Kizito Ogedi Alakwe, Ngozi Okpara
doaj   +1 more source