Results 51 to 60 of about 4,183 (267)

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Physiological responses of caprines raised under different types of covering [PDF]

Engenharia Agrícola, 2013
Thermal discomfort inside facilities is one of the factors responsible for low productivity of caprines in the Brazilian Northeast region, because inadequate weather conditions can cause elevated rectal temperature, increased respiratory rate, decreased ...
Celso Y. Kawabata, Lindalva de A. de Jesus, Ana Paula V. da Silva, Thiago V. R. de Sousa, Luis F. B. da Cruz   +4 more
doaj   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

INFRARED THERMOGRAPHY FOR DETERMINING TRAY TEMPERATURE IN LETTUCE PRODUCTION [PDF]

Engenharia Agrícola, 2019
This research was carried out in Recife, PE, Brazil, and aimed to assess the variation of the surface temperature of trays and substrate in the production of lettuce seedlings and its influence on the final product.
Sávio D. L. Cavalcanti, Héliton Pandorfi, Cristiane Guiselini, Dimas Menezes, Luiz A. de A. Neto   +4 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

The Marketplace’s Ambiences During the French Colonial Period in an Algerian Oasis: The ‘Al-Gh’deer’ Square in the Oasis of Sidi-Okba (Biskra, Algeria)

Architecture
This study investigates the traditional life within Al-Gh’deer Market Square, which constitutes a fundamental component of the vernacular urban fabric of Sidi Okba’s old city from a sensorial perspective.
Marwa Mansouri, Azeddine Belakehal
doaj   +1 more source

Productive losses on broiler preslaughter operations: effects of the distance from farms to abattoirs and of lairage time in a climatized holding area Perdas produtivas nas operações pré-abate de frangos de corte: efeito da distância entre as granjas e os abatedouros e do tempo de espera em galpão climatizado

Revista Brasileira de Zootecnia, 2010
This work aimed to assess the effects of preslaughter lairage time on the welfare and mortality of broilers transported in different farm-abattoir distances. It was evaluated 215 poultry transport trucks from a commercial poultry slaughterhouse from 2006
Frederico Márcio Corrêa Vieira, Iran José Oliveira da Silva, José Antonio Delfino Barbosa Filho, Afrânio Márcio Corrêa Vieira   +3 more
doaj   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

INGESTIVE BEHAVIOR OF NATIVE SHEEP KEPT UNDER A CONTROLLED ENVIRONMENT AT DIFFERENT TEMPERATURES [PDF]

Engenharia Agrícola
The purpose of this research was to evaluate the ingestive behavior of 24 adult male sheep from the Santa Inês, Morada Nova, Soinga, and without defined racial standard breeds, kept in a controlled environment (climatic chamber), at thermoneutral ...
Felipe L. Furtado, José P. Lopes Neto, Dermeval A. Furtado, Raimundo C. M. Rodrigues, Neila L. Ribeiro   +4 more
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source