Results 51 to 60 of about 62,562 (308)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Influence of Retail Atmospherics as Nonverbal Communication on Purchase Behaviour in the Nigerian Retail Environment

Journal of Marketing and Consumer Behaviour in Emerging Markets, 2017
This paper focuses on unravelling the impact of atmospherics on shopper purchase behaviour in emerging markets like Nigeria and attempts to isolate the atmospheric cue that is the most signifi cant predictor of shopper purchase decisions. The paper seeks
Kizito Ogedi Alakwe, Ngozi Okpara
doaj   +1 more source

INFRARED THERMOGRAPHY FOR DETERMINING TRAY TEMPERATURE IN LETTUCE PRODUCTION [PDF]

Engenharia Agrícola, 2019
This research was carried out in Recife, PE, Brazil, and aimed to assess the variation of the surface temperature of trays and substrate in the production of lettuce seedlings and its influence on the final product.
Sávio D. L. Cavalcanti, Héliton Pandorfi, Cristiane Guiselini, Dimas Menezes, Luiz A. de A. Neto   +4 more
doaj   +1 more source

Psychoacoustic Considerations in Surround Sound with Height [PDF]

, 2014
This paper presents recent research findings in the psychoacoustics of 3D multichannel sound recording and rendering. The addition of height channels in new reproduction formats such as Auro-3D, Dolby Atmos and 22.2, etc. enhances the perceived spatial
Gribben, Christopher, Lee, Hyunkook, Wallis, Rory   +2 more
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Deep Memory Networks for Attitude Identification

, 2017
We consider the task of identifying attitudes towards a given set of entities from text. Conventionally, this task is decomposed into two separate subtasks: target detection that identifies whether each entity is mentioned in the text, either explicitly ...
Chang C.-C., Collobert R., De Marneffe M.-C., Faulkner A., Gimpel K., Glorot X., Hasan K. S., Hermann K. M., Irsoy O., Jiang L., Kingma D., Kobayashi N., Le Q. V., Li F., Mikolov T., Mohammad S. M., Popescu A., Socher R., Socher R., Sukhbaatar S., Vo D.-T., Walker M. A., Wang S., Zhang M., Zirn C.   +24 more
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

INGESTIVE BEHAVIOR OF NATIVE SHEEP KEPT UNDER A CONTROLLED ENVIRONMENT AT DIFFERENT TEMPERATURES [PDF]

Engenharia Agrícola
The purpose of this research was to evaluate the ingestive behavior of 24 adult male sheep from the Santa Inês, Morada Nova, Soinga, and without defined racial standard breeds, kept in a controlled environment (climatic chamber), at thermoneutral ...
Felipe L. Furtado, José P. Lopes Neto, Dermeval A. Furtado, Raimundo C. M. Rodrigues, Neila L. Ribeiro   +4 more
doaj   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source