Results 51 to 60 of about 10,916 (310)

INGESTIVE BEHAVIOR OF NATIVE SHEEP KEPT UNDER A CONTROLLED ENVIRONMENT AT DIFFERENT TEMPERATURES [PDF]

Engenharia Agrícola
The purpose of this research was to evaluate the ingestive behavior of 24 adult male sheep from the Santa Inês, Morada Nova, Soinga, and without defined racial standard breeds, kept in a controlled environment (climatic chamber), at thermoneutral ...
Felipe L. Furtado, José P. Lopes Neto, Dermeval A. Furtado, Raimundo C. M. Rodrigues, Neila L. Ribeiro   +4 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

The ambience aspect of colour and lighting in Tanamera Wellness Spa Centre / Nureen Syazmeen Shaiful Anuar [PDF]

, 2022
The ambience in spas have become the most important function in enhancing health, beauty, and relaxation through self -care treatments. Because the spa has become a staple of recreation for generations of people who want to escape the noise of everyday ...
Shaiful Anuar, Nureen Syazmeen
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Productive losses on broiler preslaughter operations: effects of the distance from farms to abattoirs and of lairage time in a climatized holding area Perdas produtivas nas operações pré-abate de frangos de corte: efeito da distância entre as granjas e os abatedouros e do tempo de espera em galpão climatizado

Revista Brasileira de Zootecnia, 2010
This work aimed to assess the effects of preslaughter lairage time on the welfare and mortality of broilers transported in different farm-abattoir distances. It was evaluated 215 poultry transport trucks from a commercial poultry slaughterhouse from 2006
Frederico Márcio Corrêa Vieira, Iran José Oliveira da Silva, José Antonio Delfino Barbosa Filho, Afrânio Márcio Corrêa Vieira   +3 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

The Marketplace’s Ambiences During the French Colonial Period in an Algerian Oasis: The ‘Al-Gh’deer’ Square in the Oasis of Sidi-Okba (Biskra, Algeria)

Architecture
This study investigates the traditional life within Al-Gh’deer Market Square, which constitutes a fundamental component of the vernacular urban fabric of Sidi Okba’s old city from a sensorial perspective.
Marwa Mansouri, Azeddine Belakehal
doaj   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Development of a New Analytical Model for the Study of the Urban and Architectural Sound Ambiance: The Topological Approach

Proceedings of the International Conference of Contemporary Affairs in Architecture and Urbanism-ICCAUA, 2019
Research in the field of ambiences has clearly evolved in our era, the field of investigation lists all the typologies of space ranging from architectural to urban space.
Selma SARAOUI, Azeddine Belakehal, Abdelghani ATTAR, Amar BENNADJI   +3 more
doaj   +1 more source