Results 131 to 140 of about 37,190 (246)

Bacillus Licheniformis‐Induced Cognitive Decline in Mice Linking Gut Microbiota Dysbiosis, Metabolic Perturbations, and Hippocampal Neuroinflammation

open access: yesAdvanced Science, EarlyView.
Chronic oral administration of specific probiotic strains triggers gut microbiota dysbiosis and systemic metabolic perturbations in mice. Multi‐omics profiling reveals subsequent hippocampal glial remodeling and neuroinflammation, which are linked to cognitive impairment.
Yibin Lin   +15 more
wiley   +1 more source

Microenvironment‐Responsive Biomimetic Hydrogels Delivering Cistanche Deserticola‐Derived Nanovesicles for Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
An injectable, microenvironment‐responsive hydrogel (HAPOCS@CDNVs) is developed for sustained delivery of Cistanche deserticola‐derived nanovesicles (CDNVs). By scavenging ROS, restoring mitochondrial function, and attenuating SASP, this platform effectively suppresses nucleus pulposus cell senescence and facilitates extracellular matrix reconstruction,
Ning Xu   +11 more
wiley   +1 more source

Interface‐Mediated Self‐Rectifying CsCuCl3 Memristors With Tunable Thresholds for Reconfigurable Neuromorphic Computing

open access: yesAdvanced Science, EarlyView.
Interface‐mediated CsCuCl3 memristors achieve self‐rectification and tunable thresholds, enabling selector‐free 8 × 8 arrays with > 105 ON/OFF and > 104 rectification. Supporting dual‐mode neuromorphic computing, negative thresholds preserve low‐light recognition accuracy (91%), while positive thresholds enable sparsity‐aware edge computing.
Qingwei Shi   +9 more
wiley   +1 more source

Ambient Ionization Mass Spectrometry Imaging by Desorption Electrospray Ionization (DESI)

open access: yesJournal of the Mass Spectrometry Society of Japan, 2019
Akira Motoyama, Keishi Kihara
openaire   +2 more sources

Solute‐Induced Modulation of Hydrogen Bonding, Ion Hydration, and Protonation in Hydrogels for Enhanced Microwave Absorption

open access: yesAdvanced Science, EarlyView.
Systematic solute screening reveals how noncovalent interactions regulate dielectric loss in P(AA‐co‐AM) hydrogels. By tuning proton conduction, ion hydration, and hydrogen‐bond interactions, the dielectric response can be precisely controlled, enabling tailored hydrogels with broadband microwave absorption and providing a general strategy for ...
Zijing Li   +7 more
wiley   +1 more source

Spray‐Dried mRNA‐LNP Powder Enabling Multi‐Route Delivery With 3‐Year Refrigerated Stability

open access: yesAdvanced Science, EarlyView.
Spray‐dried mRNA‐LNP powder with trehalose matrix enables reconstitution for parenteral delivery or direct administration via pulmonary and sublingual routes, maintaining protein expression comparable to liquid controls. The thermostable powder preserves colloidal stability, mRNA integrity, and biological activity for over 3 years at 2°C–8°C, while ...
Ashish Sarode   +4 more
wiley   +1 more source

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