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Ambient Ionization Mass Spectrometry: A Tutorial
Analytica Chimica Acta, 2011Ambient ionization is a set of mass spectrometric ionization techniques performed under ambient conditions that allows the direct analysis of sample surfaces with little or no sample pretreatment. Using combinations of different types of sample introduction systems and ionization methods, several novel techniques have been developed over the last few ...
Min-Zong Huang +2 more
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Advances in Ambient Ionization for Mass Spectrometry
Chinese Journal of Analytical Chemistry, 2018Abstract Over the past decade, ambient mass spectrometry (AMS) has become an important scientific research tool which has been widely used in various important fields such as pharmaceuticals, food, environment, public safety, clinic diagnosis and so on.
ZHANG Hua, Huan-Wen Chen, Ke-Ke Huang
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Progress in applications of ambient ionization mass spectrometry for lipids identification [PDF]
Lipids are indispensable components of living organisms and play pivotal roles in cell-membrane fluidity, energy provision, and neurotransmitter transmission and transport. Lipids can act as potential biomarkers of diseases given their abilities to indicate cell-growth status.
Xiao-Rong, Wang +3 more
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Mass Spectrometry Imaging Techniques: Non-Ambient and Ambient Ionization Approaches
Critical Reviews in Analytical ChemistryMolecular information can be acquired from sample surfaces in real time using a revolutionary molecular imaging technique called mass spectrometry imaging (MSI). The technique can concurrently provide high spatial resolution information on the spatial distribution and relative proportion of many different compounds.
Ahsan Habib, Lei Bi
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Ambient Ionization Mass Spectrometry: Application and Prospective
Critical Reviews in Analytical Chemistry, 2022Mass spectrometry (MS) is a formidable analytical tool for the analysis of non-polar to polar compounds individually and/or from mixtures, providing information on the molecular weights and chemical structures of the analytes. During the last more than one-decade, ambient ionization mass spectrometry (AIMS) has developed quickly, producing a wide range
Lulu, Shi +5 more
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Temperature-Tuning Desorption Ionization for Ambient Mass Spectrometry
Analytical Chemistry, 2023In the past decade, mass spectrometry (MS) has been widely used for a broad range of on-site applications. This is largely attributed to the rapid advancement of technologies, such as ambient ionization and mass spectrometer miniaturization. Here, we report the development of the temperature-tuning desorption ionization (TTDI) method for versatile on ...
Ningxi Li +6 more
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Ambient Ionization Mass Spectrometry
Annual Review of Analytical Chemistry, 2010Mass spectrometric ionization methods that operate under ambient conditions and require minimal or no sample pretreatment have attracted much attention in such fields as biomedicine, food safety, antiterrorism, pharmaceuticals, and environmental pollution.
Min-Zong, Huang +4 more
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Nanotip Ambient Ionization Mass Spectrometry
Analytical Chemistry, 2016A method called nanotip ambient ionization mass spectrometry (NAIMS) is described, which applies high voltage between a tungsten nanotip and a metal plate to generate a plasma in which ionized analytes on the surface of the metal plate are directed to the inlet and analyzed by a mass spectrometer. The dependence of signal intensity is investigated as a
Zhenpeng, Zhou +3 more
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Forensic applications of ambient ionization mass spectrometry
Analytical and Bioanalytical Chemistry, 2009This review highlights and critically assesses forensic applications in the developing field of ambient ionization mass spectrometry. Ambient ionization methods permit the ionization of samples outside the mass spectrometer in the ordinary atmosphere, with minimal sample preparation.
Ifa, DR +3 more
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Detection of drugs in urine by ambient direct ionization mass spectrometry
Chinese Journal of Chromatography, 2022According to the Report of Drug Situation in China (2020), the growth rate of the number of drug abusers in China has decreased, but the number of drug abusers is still large. An efficient screening method is necessary for controlling drug abuse. As an important type of biological sample, urine is widely used for the rapid screening of drug addicts ...
Shiling, Xiong +6 more
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