Results 31 to 40 of about 147,339 (190)

Ambroxol: A potential therapeutics against neurodegeneration

Health Sciences Review, 2023
Ambroxol hydrochloride is a pharmacological chaperone approved by FDA as an expectorant. Currently, it is used as an antitussive and anti-asthmatic agent.
Prajwal Dhanve, Punita Aggarwal, Sourabh Choure, Devendra K. Dhaked, Sugato Banerjee   +4 more
doaj   +1 more source

Validasi Metode Analisis Klorfeniramin Maleat Dan Guaifenesin Menggunakan Kromatografi Cair Kinerja Tinggi Serta Aplikasinya Dalam Sediaan Sirup [PDF]

, 2017
The combination of CTM and GG is often used as an active substances to relieve symptoms of cough and cold. The concentration of CTM and GG in syrup are very low, so that it need validated determination method to ensure therapeutic dose. The purposes of
Afifah, I. (Ira), Budiarti, A. (Aqnes)
core   +5 more sources

A quality-by-design eco-friendly UV-HPLC method for the determination of four drugs used to treat symptoms of common cold and COVID-19

Scientific Reports, 2023
An optimization approach based on full factorial design was employed for developing an HPLC–UV method for simultaneous determination of a quaternary mixture used for the treatment of symptoms related to common cold and COVID-19. The quaternary mixture is
Nora A. Abdallah, Mona E. Fathy, Manar M. Tolba, Amina M. El-Brashy, Fawzia A. Ibrahim   +4 more
doaj   +1 more source

Evaluation of safety and efficacy of inhaled ambroxol in hospitalized adult patients with mucopurulent sputum and expectoration difficulty

Frontiers in Medicine, 2023
BackgroundAmbroxol is a widely used mucoactive drug in sputum clearance of respiratory diseases taken orally and by injection. However, there is a paucity of evidence for inhaled ambroxol in sputum clearance.MethodsThis study performed a multicenter ...
Zeguang Zheng, Kai Yang, Ni Liu, Xiuhua Fu, Huijie He, Hong Chen, Peijun Xu, Jing Wang, Maofeng Liu, Yuling Tang, Fengzi Zhao, Shufeng Xu, Xiaowei Yu, Jichang Han, Bo Yuan, Bin Jia, Guifen Pang, Yantong Shi, Min Kuang, Haiyan Shao, Hao Xiong, Jia He, Yuanyuan Pan, Rongchang Chen   +23 more
doaj   +1 more source

Flow injection analysis using carbon film resistor electrodes for amperometric determination of ambroxol [PDF]

, 2008
Flow injection analysis (FIA) using a carbon film sensor for amperometric detection was explored for ambroxol analysis in pharmaceutical formulations.
Angnes, Lúcio, Brett, Christopher M. A., Felix, Fabiana S.   +2 more
core   +1 more source

Biodegradable Chitosan-Based Ambroxol Hydrochloride Microspheres: Effect of Cross-Linking Agents [PDF]

Journal of Young Pharmacists, 2011
The objective of this study was to investigate the influence of type of cross-linking method used on the properties of ambroxol hydrochloride microspheres such as encapsulation efficiency, particle size, and drug release. Microspheres were prepared by solvent evaporation technique using chitosan as a matrix-forming agent and cross-linked using ...
Gangurde, HH, Chavan, NV, Mundada, AS, Derle, DV, Tamizharasi, S   +4 more
openaire   +2 more sources

Development of a new ultra-high performance liquid chromatography - tandem mass spectrometry method for determination of ambroxol hydrochloride in serum with pharmacokinetic application [PDF]

Hemijska Industrija, 2016
Ambroxol hydrochloride is an expectorant agent, successfully applied in mucolytic therapy for acute and chronic bronchopulmonary diseases. The drug regulates not only mucus secretion but also showed antioxidant, anti-inflammatory and local ...
Vujović Maja M., Jokanović Milan, Nikolić Goran M.   +2 more
doaj   +1 more source

Electrochemical Methods for Quantitative Estimation of Ambroxol Hydrochloride in drug for the Treatment of Asthmatic Bronchitis

International Journal of Electrochemical Science, 2021
This study presented the electrochemical quantitative estimation of ambroxol hydrochloride (AHC) as drug safety for asthmatic bronchitis on ZnO nanoparticles electrodeposited on carboxylated CNTs modified glassy carbon electrode (ZnO NPs/c-CNTs/GCE). The
Lina Li
doaj   +1 more source

Ambroxol improves lysosomal biochemistry in glucocerebrosidase mutation-linked Parkinson disease cells. [PDF]

, 2014
Gaucher disease is caused by mutations in the glucocerebrosidase gene, which encodes the lysosomal hydrolase glucosylceramidase. Patients with Gaucher disease and heterozygous glucocerebrosidase mutation carriers are at increased risk of developing ...
Abramov, AY, Chau, KY, Cooper, JM, Foltynie, T, Gegg, M, Hughes, D, Magalhaes, J, McNeill, A, Mehta, A, Schapira, AH, Shen, C   +10 more
core   +1 more source

Effects of ambroxol on the autophagy-lysosome pathway and mitochondria in primary cortical neurons [PDF]

, 2018
Glucocerebrosidase (GBA1) mutations are the major genetic risk factor for Parkinson's Disease (PD). The pathogenic mechanism is still unclear, but alterations in lysosomal-autophagy processes are implicated due to reduction of mutated glucocerebrosidase (
Gegg, ME, Magalhaes, J, Migdalska-Richards, A, Schapira, AH   +3 more
core   +1 more source