Results 1 to 10 of about 2,537 (184)

A novel Ambn-IRESCre mouse line allows ameloblast-specific Smad4 silencing [PDF]

Frontiers in Physiology
IntroductionFor more than two decades, enamel researchers have primarily used the keratin-14-Cre (Krt14-Cre) driver line to study ameloblast-specific molecular activities.
Rucha Arun Bapat, Yanbin Ji, Marziyeh Aghazadeh, Alexis E. Bauer, David C. Evans, Joseph G. Hacia, Yan Zhou, Yan Zhou, Michael L. Paine, Michael L. Paine   +9 more
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Odontogenesis-associated phosphoprotein (ODAPH) Promotes Ameloblast adhesion and alkaline phosphatase (ALP) expression via LAMC2/ ITGB6/TGF-β1 signaling pathway. [PDF]

PLoS ONE
Recessive hypomineralized amelogenesis imperfecta has been linked to mutations in Odontogenesis-Associated Phosphoprotein (ODAPH). Consistent with human phenotypes, Odaph-null mice exhibit defective enamel mineralization with ameloblast detachment from ...
Mingyue Li, Jie Zhang, Shuang Xiao, Xinyang Liu, Shuai Song, Xiaoyuan Ye, Ruonan Bi, Yuguang Gao, Li Zhang   +8 more
doaj   +2 more sources

The role of the TGF-β1 signaling pathway in the process of amelogenesis [PDF]

Frontiers in Physiology
Amelogenesis is a highly regulated process involving multiple signaling pathways, among which the transforming growth factor-β1 (TGF-β1) signaling pathway plays a pivotal role in enamel formation.
Xiaoxue Ma, Yunjing Ma, Zhiyong Lin, Mei Ji   +3 more
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Small molecules direct the generation of ameloblast-like cells from human embryonic stem cells [PDF]

Stem Cell Research & Therapy
Background Ameloblasts present a promising avenue for the investigation of enamel and tooth regeneration. Previous protocols for directing the differentiation of human embryonic stem cells (hESCs) into dental epithelial (DE) cells involving the need for ...
Ximei Zhu, YiMeng Zhao, Xiaofan Bai, Qiannan Dong, Chunli Tian, Ruilin Sun, Congjuan Yan, Jianping Ruan, Zhongbo Liu, Jianghong Gao   +9 more
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Epiprofin Transcriptional Activation Promotes Ameloblast Induction From Mouse Induced Pluripotent Stem Cells via the BMP-Smad Signaling Axis

Frontiers in Bioengineering and Biotechnology, 2022
The transcriptional regulation of induced pluripotent stem cells (iPSCs) holds promise for their directed differentiation into ameloblasts, which are usually lost after tooth eruption.
Xinchao Miao, Xinchao Miao, Kunimichi Niibe, Yunyu Fu, Maolin Zhang, Maolin Zhang, Praphawi Nattasit, Yumi Ohori-Morita, Takashi Nakamura, Xinquan Jiang, Hiroshi Egusa, Hiroshi Egusa   +11 more
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Amelogenin and alkaline phosphatase expression in ameloblast after saltwater fish consumption in pregnant mice (Mus musculus)

Dental Journal, 2023
Background: The intricate process of tooth formation during embryonic development ensures sufficient nutrition for the growth of healthy dental tissues.
Sandy Christiono, Seno Pradopo, I Ketut Sudiana, Islamy Rahma Hutami, Regilia Shinta Mayangsari, Yayun Siti Rochmah, Zurairah Ibrahim   +6 more
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Correlation of amyloid and ameloblast‐associated proteins to odontogenic cysts and tumors: A cross‐sectional study

Health Science Reports, 2023
Background and Aims Odontogenic cysts and tumors often form hard and soft structures that resemble odontogenesis. It is well known that amyloid is produced in Pindborg tumors; however, it is still debatable whether it is also formed in other odontogenic ...
Haider H. Al‐Qazzaz, Bashar H. Abdullah, Omar S. Museedi   +2 more
doaj   +1 more source

Mobility gene expression differences among wild-type, Mmp20 null and Mmp20 over-expresser mice plus visualization of 3D mouse ameloblast directional movement

Scientific Reports, 2023
Enamel forming ameloblasts move away from the dentino-enamel junction and also move relative to each other to establish enamel shape during the secretory stage of enamel development.
Masashi Shin, Aya Matsushima, Jun-ichi Nagao, Yoshihiko Tanaka, Hidemitsu Harada, Koji Okabe, John D. Bartlett   +6 more
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Significance of pH cyclization in amelogenesis

Fogorvosi Szemle, 2021
The process of amelogenesis is well understood at the histomorphological level, but the regulation of crystal formation and the underlying molecular mechanisms are still largely unknown.
Róbert Rácz, Martin C. Steward, Pamela Denbesten, Gábor Varga, Beáta Kerémi   +4 more
doaj   +1 more source

Evaluation of the Effects of Amoxicillin on Tooth Development in Rats by Histological and Histomorphometric Study [PDF]

Archives of Razi Institute, 2023
Amoxicillin is one of the most commonly prescribed antibiotics in children. As a result, it is prescribed as the first line of defence against cutaneous, gastrointestinal, and respiratory infections.
T Sabah, N. M. H AL-Ghaban
doaj   +1 more source