Results 41 to 50 of about 5,719 (245)

4-phenylbutyrate Mitigates Fluoride-Induced Cytotoxicity in ALC Cells

open access: yesFrontiers in Physiology, 2017
Chronic fluoride over-exposure during pre-eruptive enamel development can cause dental fluorosis. Severe dental fluorosis is characterized by porous, soft enamel that is vulnerable to erosion and decay.
Maiko Suzuki   +3 more
doaj   +1 more source

The effect of inhibiting p38 MAPK on the expression of genes related to enamel development in mice

open access: yes口腔疾病防治, 2021
Objective To study the effect of p38 mitogen activated protein kinase (p38 MAPK) on the expression of genes related to enamel development in the enamel epithelium and to provide a basis for the study of the molecular mechanism of enamel development ...
LUO Xiaona   +4 more
doaj   +1 more source

Ameloblastic fibroma

open access: yesJournal of Oral and Maxillofacial Pathology, 2012
Ameloblastic fibroma is a rare odontogenic tumor comprising neoplastic epithelial and mesenchymal tissues. This lesion was previously considered to be a benign lesion with very limited recurrence rate and malignant transformation. However, recent reports have suggested that this lesion has the potential for recurrence and malignant transformation.
Rao, Srinivas Ponnam   +2 more
openaire   +3 more sources

Modeling ameloblast-matrix interactions using 3D cell culture

open access: yesFrontiers in Physiology, 2022
The distinct morphology adopted by ameloblasts during amelogenesis is highly stage specific and involved intimately with the development of a hierarchical enamel microstructure.
Gayathri Visakan   +3 more
doaj   +1 more source

Intravesicular Phosphatase PHOSPHO1 Function in Enamel Mineralization and Prism Formation

open access: yesFrontiers in Physiology, 2017
The transport of mineral ions from the enamel organ-associated blood vessels to the developing enamel crystals involves complex cargo packaging and carriage mechanisms across several cell layers, including the ameloblast layer and the stratum intermedium.
Mirali Pandya   +7 more
doaj   +1 more source

No Change in Bicarbonate Transport but Tight-Junction Formation Is Delayed by Fluoride in a Novel Ameloblast Model

open access: yesFrontiers in Physiology, 2017
We have recently developed a novel in vitro model using HAT-7 rat ameloblast cells to functionally study epithelial ion transport during amelogenesis. Our present aims were to identify key transporters of bicarbonate in HAT-7 cells and also to examine ...
Róbert Rácz   +9 more
doaj   +1 more source

Deciphering the functions of Stromal Interaction Molecule-1 in amelogenesis using AmelX-iCre mice

open access: yesFrontiers in Physiology, 2023
Introduction: The intracellular Ca2+ sensor stromal interaction molecule 1 (STIM1) is thought to play a critical role in enamel development, as its mutations cause Amelogenesis Imperfecta (AI).
Raed Said   +10 more
doaj   +1 more source

Connexin 43-Mediated Gap Junction Communication Regulates Ameloblast Differentiation via ERK1/2 Phosphorylation

open access: yesFrontiers in Physiology, 2021
Connexin 43 (Cx43) is an integral membrane protein that forms gap junction channels. These channels mediate intercellular transport and intracellular signaling to regulate organogenesis.
Aya Yamada   +12 more
doaj   +1 more source

Temporal and spatial expression of TGF-b 2 in tooth crown development in mouse first lower molar

open access: yesEuropean Journal of Histochemistry, 2009
Transforming Growth Factor b2 (TGF-b2) is involved in the regulation of many important cellular processes during tooth development. In this study we systematically characterized the expression pattern of TGF-b2 in vivo and further analyzed its possible ...
JY Li, B Hu, XJ Wang, SL Wang
doaj   +1 more source

Single-Cell RNA-Sequencing From Mouse Incisor Reveals Dental Epithelial Cell-Type Specific Genes

open access: yesFrontiers in Cell and Developmental Biology, 2020
Dental epithelial stem cells give rise to four types of dental epithelial cells: inner enamel epithelium (IEE), outer enamel epithelium (OEE), stratum intermedium (SI), and stellate reticulum (SR).
Yuta Chiba   +11 more
doaj   +1 more source

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