Results 41 to 50 of about 5,719 (245)
4-phenylbutyrate Mitigates Fluoride-Induced Cytotoxicity in ALC Cells
Chronic fluoride over-exposure during pre-eruptive enamel development can cause dental fluorosis. Severe dental fluorosis is characterized by porous, soft enamel that is vulnerable to erosion and decay.
Maiko Suzuki +3 more
doaj +1 more source
The effect of inhibiting p38 MAPK on the expression of genes related to enamel development in mice
Objective To study the effect of p38 mitogen activated protein kinase (p38 MAPK) on the expression of genes related to enamel development in the enamel epithelium and to provide a basis for the study of the molecular mechanism of enamel development ...
LUO Xiaona +4 more
doaj +1 more source
Ameloblastic fibroma is a rare odontogenic tumor comprising neoplastic epithelial and mesenchymal tissues. This lesion was previously considered to be a benign lesion with very limited recurrence rate and malignant transformation. However, recent reports have suggested that this lesion has the potential for recurrence and malignant transformation.
Rao, Srinivas Ponnam +2 more
openaire +3 more sources
Modeling ameloblast-matrix interactions using 3D cell culture
The distinct morphology adopted by ameloblasts during amelogenesis is highly stage specific and involved intimately with the development of a hierarchical enamel microstructure.
Gayathri Visakan +3 more
doaj +1 more source
Intravesicular Phosphatase PHOSPHO1 Function in Enamel Mineralization and Prism Formation
The transport of mineral ions from the enamel organ-associated blood vessels to the developing enamel crystals involves complex cargo packaging and carriage mechanisms across several cell layers, including the ameloblast layer and the stratum intermedium.
Mirali Pandya +7 more
doaj +1 more source
We have recently developed a novel in vitro model using HAT-7 rat ameloblast cells to functionally study epithelial ion transport during amelogenesis. Our present aims were to identify key transporters of bicarbonate in HAT-7 cells and also to examine ...
Róbert Rácz +9 more
doaj +1 more source
Deciphering the functions of Stromal Interaction Molecule-1 in amelogenesis using AmelX-iCre mice
Introduction: The intracellular Ca2+ sensor stromal interaction molecule 1 (STIM1) is thought to play a critical role in enamel development, as its mutations cause Amelogenesis Imperfecta (AI).
Raed Said +10 more
doaj +1 more source
Connexin 43 (Cx43) is an integral membrane protein that forms gap junction channels. These channels mediate intercellular transport and intracellular signaling to regulate organogenesis.
Aya Yamada +12 more
doaj +1 more source
Temporal and spatial expression of TGF-b 2 in tooth crown development in mouse first lower molar
Transforming Growth Factor b2 (TGF-b2) is involved in the regulation of many important cellular processes during tooth development. In this study we systematically characterized the expression pattern of TGF-b2 in vivo and further analyzed its possible ...
JY Li, B Hu, XJ Wang, SL Wang
doaj +1 more source
Single-Cell RNA-Sequencing From Mouse Incisor Reveals Dental Epithelial Cell-Type Specific Genes
Dental epithelial stem cells give rise to four types of dental epithelial cells: inner enamel epithelium (IEE), outer enamel epithelium (OEE), stratum intermedium (SI), and stellate reticulum (SR).
Yuta Chiba +11 more
doaj +1 more source

