Molar-Incisor Hypomineralisation in Children: The Essential Role of Paediatricians. [PDF]
ABSTRACT Aim Molar‐incisor hypomineralisation is a developmental enamel defect characterised by lower mineral content in the tooth's outer layer, discoloured and structurally fragile teeth that are more prone to sensitivity, breakdown and caries. This review aims to summarise current knowledge on molar‐incisor hypomineralisation and highlight key ...
Stancati S +3 more
europepmc +2 more sources
Enamel Maturation as a Systems Physiology: Ion Transport and Pi Flux [PDF]
Dental enamel, the final product of amelogenesis, is a highly mineralized bioceramic that becomes acellular and non-regenerating after tooth eruption. This paper reviews literature that explores inorganic phosphate (Pi) transport during the process of ...
Mehrnaz Zarinfar +4 more
doaj +2 more sources
Full Mouth Rehabilitation with All-Ceramic Restorations in a Patient with Amelogenesis Imperfecta: A Case Report with 10-Year Follow-Up [PDF]
Background: Amelogenesis imperfecta (AI) includes a group of inherited disorders that affect enamel formation, both in quality and quantity. It may cause anomalies in a number of teeth or a group of teeth, or it may be present in the whole dentition. The
Stefanos Kourtis
doaj +2 more sources
Reduced Dietary Protein Induces Changes in the Dental Proteome. [PDF]
Low dietary protein (10%) from normal (20%) does change protein expression in tooth proteome and alter developmental pathways. Among the significant protein expressions changes are actin‐based myosins, tooth, and bone development proteins. Perplexingly tooth size is not altered, suggesting more nuanced phenotypic response to low dietary protein in ...
Burroughs RW, Percival CJ, Vitek NS.
europepmc +2 more sources
Amelogenesis Imperfecta; Genes, Proteins, and Pathways
Amelogenesis imperfecta (AI) is the name given to a heterogeneous group of conditions characterized by inherited developmental enamel defects. AI enamel is abnormally thin, soft, fragile, pitted and/or badly discolored, with poor function and aesthetics,
Claire E L Smith +2 more
exaly +3 more sources
Application of Artificial Intelligence in Detecting Dental Anomalies: Current Models, Imaging Modalities, and Future Directions. [PDF]
ABSTRACT Background and Aim As dental anomalies can significantly affect esthetic and function, early detection and diagnosis are crucial for treatment and minimizing potential negative effects. Artificial intelligence (AI) has emerged as a promising tool for the segmentation and detection of dental anomalies in number, morphology, size, position, and ...
Zarabadi MS +4 more
europepmc +2 more sources
THE EFFECT OF AMOXICILLIN ON THE SECRETORY STAGE OF AMELOGENESIS IN RATS [PDF]
Introduction: Molar–incisor hypomineralization is a developmental enamel defect affecting first permanent molars and incisors. The intake of antibiotics during pregnancy and early childhood has been associated with molar incisor hypomineralization ...
Khadiga Kawana +3 more
doaj +1 more source
Amelogenesis imperfecta (AI) represents a group of developmental conditions, genomic in origin, which affect the structure and clinical appearance of enamel of all or nearly all the teeth in a more or less equal manner, and which may be associated with morphologic or biochemical changes elsewhere in the body.
Aldred Michael +2 more
openaire +3 more sources
Deciphering the functions of Stromal Interaction Molecule-1 in amelogenesis using AmelX-iCre mice
Introduction: The intracellular Ca2+ sensor stromal interaction molecule 1 (STIM1) is thought to play a critical role in enamel development, as its mutations cause Amelogenesis Imperfecta (AI).
Raed Said +10 more
doaj +1 more source
Enamel Defects Associated With Dentin Sialophosphoprotein Mutation in Mice
Dentin sialophosphoprotein (DSPP) is an extracellular matrix protein that is highly expressed in odontoblasts, but only transiently expressed in presecretory ameloblasts during tooth development. We previously generated a knockin mouse model expressing a
Tian Liang +6 more
doaj +1 more source

