Results 21 to 30 of about 508 (131)

Three-Dimensional Culture of Ameloblast-Originated HAT-7 Cells for Functional Modeling of Defective Tooth Enamel Formation

Frontiers in Pharmacology, 2021
Background: Amelogenesis, the formation of dental enamel, is well understood at the histomorphological level but the underlying molecular mechanisms are poorly characterized.
Anna Földes, Thanyaporn Sang-Ngoen, Kristóf Kádár, Róbert Rácz, Ákos Zsembery, Pamela DenBesten, Martin C. Steward, Martin C. Steward, Gábor Varga   +8 more
doaj   +1 more source

Significance of pH cyclization in amelogenesis

Fogorvosi Szemle, 2021
The process of amelogenesis is well understood at the histomorphological level, but the regulation of crystal formation and the underlying molecular mechanisms are still largely unknown.
Róbert Rácz, Martin C. Steward, Pamela Denbesten, Gábor Varga, Beáta Kerémi   +4 more
doaj   +1 more source

Identification of stages of amelogenesis in the continuously growing mandiblular incisor of C57BL/6J male mice throughout life using molar teeth as landmarks

Frontiers in Physiology, 2023
Continuously growing mouse incisors are widely used to study amelogenesis, since all stages of this process (i.e., secretory, transition and maturation) are present in a spatially determined sequence at any given time.
Ai Thu Bui, Ai Thu Bui, Lyudmila Lukashova, Kostas Verdelis, Kostas Verdelis, Brent Vasquez, Lasya Bhogadi, Claire M. Gabe, Claire M. Gabe, Henry C. Margolis, Henry C. Margolis, Henry C. Margolis, Elia Beniash, Elia Beniash   +13 more
doaj   +1 more source

Pathogenesis of dental fluorosis: biochemical and cellular mechanisms

Revista Facultad de Odontología Universidad de Antioquia, 2017
The mechanisms involved in the development of dental fluorosis are still unknown. The development of in vivo and in vitro models using biologically relevant concentrations of fluoride for the emergence of fluorosis has allowed suggesting hypotheses that ...
Gina Alejandra Castiblanco-Rubio, Stefania Martignon-Biermann, Jaime Eduardo Castellanos-Parra, Wilson Alfonso Mejía-Naranjo   +3 more
doaj   +1 more source

Dental anomalies in Pleistocene African hippopotamuses from Olduvai Bed II

The Anatomical Record, EarlyView.
Abstract Hippopotamuses are key palaeoenvironmental indicators in African Pleistocene ecosystems due to their ecological dependence on permanent water bodies and their frequent representation in the fossil record. This study examines dental anomalies in Hippopotamus cf. gorgops from several localities in Bed II of Olduvai Gorge (Tanzania), dated to ca.
Darío Fidalgo, Faysal Bibi, Jean‐Renaud Boisserie, Jackson K. Njau, Ignacio de la Torre   +4 more
wiley   +1 more source

Integrated microanatomy and microstructure of the maxillary tooth plate reveal a reinforced feeding system and tougher diet in Late Triassic Hyperodapedontinae (Rhynchosauria, Archosauromorpha)

The Anatomical Record, EarlyView.
Abstract Hyperodapedontine rhynchosaurs possessed a unique oral apparatus, long interpreted as an adaptation for processing abrasive and resistant plant material. However, the microanatomical and histological evidence supporting this interpretation remains poorly documented.
Caio A. Scartezini, Pedro L. B. Pruciano, Brodsky D. M. Farias, Marina B. Soares   +3 more
wiley   +1 more source

Jaw‐specific stem cell dynamics are associated with distinct enamel architecture in mouse incisors

Developmental Dynamics, EarlyView.
Abstract Background The continuously growing mouse incisor serves as a model for stem cell‐driven tooth renewal. Although mice possess maxillary and mandibular incisors, most studies have focused on the mandible. Potential differences in structure and renewal between these serially homologous organs remain insufficiently characterized.
Elias Shahin, Jihan Asmar, Sanako Takano, Jimmy K. Hu, Amnon Sharir   +4 more
wiley   +1 more source

Proteomic signatures of equine dental tooth tissues in ageing and disease

Equine Veterinary Journal, EarlyView.
Abstract Background Ageing and dental disease in horses lead to structural and functional deterioration of dental tissues, yet their molecular signatures remain poorly characterised. Understanding how these processes alter the protein composition of enamel, dentin, cementum and pulp is essential for improving equine oral health and identifying ...
Anders Jensen, Danae Emilie Zambouli, Iris Gringel, Zoe Nugent, Kazuhiro Yamamoto, Lee Cooper, Andrew J. Peffers, Guido Rocchigiani, Mandy J. Peffers   +8 more
wiley   +1 more source

WDR72 Drives Esophageal Squamous Cell Carcinoma Progression by Inhibiting Autophagy via the PI3K/Akt/mTOR Pathway

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Esophageal squamous cell carcinoma (ESCC) is an aggressive malignancy with a high rate of recurrence and metastasis, necessitating the identification of novel therapeutic targets. WD repeat‐containing protein 72 (WDR72) has been linked to various cancers, but its specific biological function and underlying mechanism in ESCC remain largely ...
Hao Wu, Zhong‐Xiang Jiang, Zheng Jiang
wiley   +1 more source

Optimizing Immunostaining of Enamel Matrix: Application of Sudan Black B and Minimization of False Positives from Normal Sera and IgGs

Frontiers in Physiology, 2017
Non-specific fluorescence from demineralized enamel matrix can significantly compromise the immunofluorescence studies and lead to false positives. Our goal was to assess degrees of non-specific binding under different conditions and try to optimize ...
Elia Beniash, Elia Beniash, Xu Yang, Alexander J. Vidunas   +3 more
doaj   +1 more source