Results 71 to 80 of about 3,132 (206)
Rho GTPases in ameloblast differentiation
During tooth development, ameloblasts differentiate from inner enamel epithelial cells to enamel-forming cells by modulating the signal pathways mediating epithelial–mesenchymal interaction and a cell-autonomous gene network.
Keishi Otsu, Hidemitsu Harada
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Enamelin is critical for ameloblast integrity and enamel ultrastructure formation. [PDF]
Mutations in the human enamelin gene cause autosomal dominant hypoplastic amelogenesis imperfecta in which the affected enamel is thin or absent. Study of enamelin knockout NLS-lacZ knockin mice revealed that mineralization along the distal membrane of ...
Jan C-C Hu+10 more
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Paleo‐evo‐devo implications of a revised conceptualization of enameloids and enamels
ABSTRACT Understanding the origin and evolution of the mineralized skeleton is crucial for unravelling vertebrate history. However, several limitations hamper our progress. The first obstacle is the lack of uniformity and clarity in the literature for the definition of the tissues of concern, especially of enameloid(s) and enamel(s), resulting in ...
Guillaume Houée+3 more
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Optical Metasurfaces for the Next‐Generation Biosensing and Bioimaging
Recent advances in this understanding of light‐matter interactions, combined with innovations in the design and fabrication of large‐scale nanostructured metasurfaces, have enabled transformative approaches to biosensing and bioimaging. This review explores innovations in refractometric sensing, surface‐enhanced spectroscopy, and super‐resolution ...
Anthony J. El‐Helou+6 more
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OPTN interacts with NRF2 to facilitate the AKT/DRP1‐mediated regulation of mitochondrial fission in the cytoplasm of SCAPs, promoting tooth root mineralisation. Additionally, OPTN maintains NRF2's nuclear translocation, enhancing the transcriptional regulation of downstream BCL2, ultimately leading to the inhibition apoptosis in SCAPs and regulate ...
Haojie Liu+9 more
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Ameloblastic Fibro–Odontoma [PDF]
A case of an amelobastic fibro-odontoma affecting a 15 year-old girl will be discussed. The characteristic radiologic and histologic features of the entity will be described.
Brenda L. Nelson, Lester D.R. Thompson
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Tissue clearing and its application in dental research
Tissue‐clearing methods can be classified into three types based on the chemical medium they employ, with each method following a set of shared general principles and essential steps. Furthermore, by integrating novel techniques such as labeling and imaging technologies, researchers can expand the applications of tissue clearing.
Lingxi Meng+6 more
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Dental Abnormalities in Congenital Ichthyoses: Case Report and Review of the Literature
ABSTRACT We describe a 1‐day old female with features of keratitis‐ichthyosis‐deafness (KID) syndrome and natal teeth. Genetic analysis confirmed GJB2 263C and A88V de novo pathogenic variants consistent with KID syndrome. Natal teeth were promptly extracted to avoid the risk of aspiration.
Sarah Maarouf+3 more
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Ameloblastic fibroma is a rare odontogenic tumor comprising neoplastic epithelial and mesenchymal tissues. This lesion was previously considered to be a benign lesion with very limited recurrence rate and malignant transformation. However, recent reports have suggested that this lesion has the potential for recurrence and malignant transformation.
Rao, Srinivas Ponnam+2 more
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New insights into the functions of enamel matrices in calcified tissues
Ameloblasts secrete enamel matrix proteins, including amelogenin, ameloblastin, enamelin, amelotin, and Apin/odontogenic ameloblast-associated protein (Apin/ODAM). Amelogenin is the major protein component of the enamel matrix.
Satoshi Fukumoto+7 more
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