Results 91 to 100 of about 5,175,501 (310)

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

[Review of] David R. Weber (Ed.), Civil Disobedience in America, A Documentary History [PDF]

open access: yes, 1979
Here is an important book which should be on the required reading list of all Americans. It is imperative reading for ethnic and minority group members. In this anthology, Mr.
Carter, George E.
core   +1 more source

Book Review: Hewitt, Nancy A. Women\u27s Activism And Social Change: Rochester, New York, 1822-1872 [PDF]

open access: yes, 2020
Scholar Nancy A. Hewitt analyzes the lives of women in antebellum Rochester, New York, focusing how they adapted to a wide variety of changes during a turbulent period in American ...
Morgan, Merritt A.
core   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

Population genetic structure and habitat connectivity for jaguar (Panthera onca) conservation in Central Belize

open access: yesBMC Genetics, 2019
Background Connectivity among jaguar (Panthera onca) populations will ensure natural gene flow and the long-term survival of the species throughout its range.
Angelica Menchaca   +11 more
doaj   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

open access: yesFEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen   +6 more
wiley   +1 more source

Primate Phenotypes: A Multi-Institution Collection of 3D Morphological Data Housed in MorphoSource

open access: yesScientific Data
The field of phenomics is experiencing unprecedented advances thanks to the rapid growth of morphological quantification based on three-dimensional (3D) imaging, online data repositories, team-oriented collaborations, and open data-sharing policies.
Sergio Almécija   +19 more
doaj   +1 more source

The Failure or Future of American Archival History: A Somewhat Unorthodox View [PDF]

open access: yes, 2000
The quality of research on American archival history has been uneven and the quantity not very impressive. This essay reviews some of the highlights of American archival history research, especially the growing interest in cultural and public history ...
Cox, Richard J
core  

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

open access: yesFEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Measuring American rents: a revisionist history. [PDF]

open access: yes
Until the end of 1977, the method used to measure changes in rent of primary residence in the U.S. consumer price index (CPI) tended to omit price changes when units changed tenants or were temporarily vacant.
Leonard I. Nakamura   +2 more
core  

Home - About - Disclaimer - Privacy