Development of human monoclonal antibodies against TARM1 by yeast display
FEBS Open Bio, EarlyView.Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source
Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte +13 more
wiley +1 more source
Study of the Chernobyl fallout in 30-km zone after construction of the Confinement
Ядерна фізика та енергетика, 2019 Radionuclides behavior on strongly contaminated territories of 30-km Chernobyl zone was studied. Samples in two layers for determination of the possible impact of works on construction of the "Shelter" object were collected. As a result, abnormal A(241Am)
M. V. Zheltonozhska +3 more
doaj +1 more source
Portable, high intensity isotopic neutron source provides increased experimental accuracy [PDF]
, 1968 Small portable, high intensity isotopic neutron source combines twelve curium-americium beryllium sources. This high intensity of neutrons, with a flux which slowly decreases at a known rate, provides for increased experimental ...
Mohr, W. C. +2 more
core +1 more source
Performance of a corona ion source for measurement of sulfuric acid by chemical ionization mass spectrometry [PDF]
, 2010 The performance of an ion source based on corona discharge has been studied. This source is used for the detection of gaseous sulfuric acid by chemical ionization mass spectrometry (CIMS) through the reaction of NO−3 ions with H2SO4.
Curtius, Joachim +3 more
core +2 more sources
Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky +8 more
wiley +1 more source
Study of actinide chemistry in saturated potassium fluoride solution [PDF]
, 1969 Study concerning the chemistry of actinides in saturated KF solution included work with neptunium, uranium, and americium. Solubilities, absorption spectra, oxidation-reduction reactions, and solid compounds which can be produced in KF solution were ...
Cohen, D., Thalmayer, C. E.
core +1 more source
Many-Body Electronic Structure of Americium metal
, 2005 We report computer based simulations of energetics, spectroscopy and electron-phonon interaction of americium using a novel spectral density functional method.
G. Kotliar +5 more
core +1 more source
Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi +19 more
wiley +1 more source
The Periodic Table\u27s 150th Anniversary [PDF]
, 2019 Word play using the names of the ...
Francis, Darryl
core +1 more source