Results 41 to 50 of about 322,084 (409)

Preparation, Characterization and Evaluation of Some New Amides as Antimicrobial Agents

Hittite Journal of Science and Engineering, 2020
The some new amide derivatives 1(a-c) and, 2d were synthesized by the two-step N-acylation of 4-nitroaniline or heterocyclic amine derivatives with acyl chlorides.
Aysel Veysioğlu, Şükriye Çakmak
doaj   +1 more source

Alkylation of N-substituted-2-phenylacetamides [PDF]

Journal of the Serbian Chemical Society, 2004
Various N-substituted phenylacetamides were alkylated using different alkylating agents under neutral and basic conditions. Reactions were performed at different reaction temperatures and in various solvents. Also, a number of various catalysts were used
Mijin Dušan Ž., Mišić-Vuković Milica M., Petrović Slobodan D.   +2 more
doaj   +1 more source

Lithium and aluminium carbamato derivatives of the utility amide 2, 2, 6, 6- tetramethylpiperidide [PDF]

, 2010
Insertion of CO2 into the metal-N bond of a series of synthetically-important alkali-metal TMP (2,2,6,6-tetramethylpiperidide) complexes has been studied.
Abram, Alan R. Kennedy, Andrews, Aresta, Armstrong, Ball, Belforte, Butler, Chang, Conway, Conway, David E. Oliver, Davies, Dell'Amico, Dell'Amico, Feier-Iova, Garcia-Álvarez, Gehrhus, Habereder, Hagadorn, Hyvärinen, Inoue, Katritzky, Knabel, Knabel, Köhn, Lappert, Lucht, Maruoka, Mulvey, Mulvey, Mulvey, Naruse, Nozaki, Otero, Otero, Otero, Rathke, Remenar, Robert E. Mulvey, Sheldrick, Stuart D. Robertson, Tanaka, Tang, Vauthey, Williard, Woodcock, Wu, Yang, Yasuda, Yasuda   +50 more
core   +1 more source

New Sorafenib Derivatives: Synthesis, Antiproliferative Activity Against Tumour Cell Lines and Antimetabolic Evaluation

Molecules, 2012
Sorafenib is a relatively new cytostatic drug approved for the treatment of renal cell and hepatocellular carcinoma. In this report we describe the synthesis of sorafenib derivatives 4a–e which differ from sorafenib in their amide part.
Branka Zorc, Jos Vanderleyden, Marijeta Kralj, Mariya Petrova, Jan Balzarini, Ana-Matea Mikecin, Zrinka Rajić, Maja Crkvenčić, Željka Babić   +8 more
doaj   +1 more source

Synthesis of C-5" and C-6"-modified α-GalCer analogues as iNKT-cell agonists [PDF]

, 2015
Alpha-Galactosyl Ceramide (α-GalCer) is a prototypical synthetic ligand of invariant natural killer T (iNKT) cells. Upon presentation by the MHC class I-like molecule CD1d, this glycolipid stimulates iNKT cells to secrete a vast amount of both pro ...
ASPESLAGH, SANDRINE, Elewaut, Dirk, Guillaume, Joren, Pauwels, Nora, Van Calenbergh, Serge, Zajonc, Dirk   +5 more
core   +1 more source

Nickel-Catalyzed 1,2-Diarylation of Simple Alkenyl Amides.

Journal of the American Chemical Society, 2018
A nickel-catalyzed conjunctive cross-coupling of simple alkenyl amides with aryl iodides and aryl boronic esters is reported. The reaction is enabled by an electron-deficient olefin (EDO) ligand, dimethyl fumarate, and delivers the desired 1,2-diarylated
J. Derosa, Roman Kleinmans, V. Tran, Malkanthi K. Karunananda, S. Wisniewski, Martin D. Eastgate, K. Engle   +6 more
semanticscholar   +1 more source

Metabolites Identification of Bioactive Compounds Daturataturin A, Daturametelin I, N-Trans-Feruloyltyramine, and Cannabisin F From the Seeds of Datura metel in Rats

Frontiers in Pharmacology, 2018
Datura metel L. is a widely used traditional herbal medicine, and withanolides and amides are the two groups of main bioactive constituents in Datura metel seeds.
Silun Xu, Yan Liu, Ling Xiang, Fan Zhou, Hongyu Li, Yongjian Su, Xinyi Xu, Qi Wang   +7 more
doaj   +1 more source

KNH2 - KH: a metal amide - hydride solid solution [PDF]

, 2016
We report for the first time the formation of a metal amide-hydride solid solution. The dissolution of KH into KNH2 leads to an anionic substitution, which decreases the interaction among NH2 - ions.
Baricco, Marcello, Bergemann, Nils, Cao, Hujun, Chierotti, Michele R., Dornheim, Martín, Garroni, Sebastian, Gobetto, Roberto, Hauback, Bjorn C., Karimi, Fahim, Klassen, Thomas, Le, Thi T., Pinatel, Eugenio, Pistidda, Claudio, Puszkiel, Julián Atilio, Santoru, Antonio, Sørby, Magnus H.   +15 more
core   +4 more sources

Highly selective transition-metal-free transamidation of amides and amidation of esters at room temperature

Nature Communications, 2018
Amide chemistry has an essential role in the synthesis of high value molecules, such as pharmaceuticals, natural products, and fine chemicals. Over the past years, several examples of transamidation reactions have been reported.
Guangchen Li, M. Szostak
semanticscholar   +1 more source

Copper-Catalyzed N-Arylation of Amides Using (S)-N-Methylpyrrolidine-2-carboxylate as the Ligand

Molecules, 2010
(S)-N-methylpyrrolidine-2-carboxylate, a derivative of natural L-proline, was found to be an efficient ligand for the copper-catalyzed Goldberg-type N-arylation of amides with aryl halides under mild conditions. A variety of N-arylamides were synthesized
Dong-Sheng Ma, Hua Zhang, Wei Wang, Lijuan Liu, Chaoyu Wang   +4 more
doaj   +1 more source