Results 51 to 60 of about 3,541 (141)

Long-Term Cropping Management Practices Affect the Biochemical Properties of an Alabama Ultisol

open access: yesSoil Systems
Interest in improving the long-term sustainability of agricultural production systems has focused on identifying management practices that promote soil health.
Dexter B. Watts   +5 more
doaj   +1 more source

The Progress of Ferroptosis of Immune Cells in the Tumor Microenvironment and Its Impact on Tumorigenesis and Development

open access: yesImmunity, Inflammation and Disease, Volume 14, Issue 1, January 2026.
The interplay between ferroptosis and the tumor immune microenvironment significantly influences the outcome of cancer immunotherapy. Inducing ferroptosis in tumor cells and immunosuppressive cells, while preventing ferroptosis in effector immune cells, emerges as a promising strategy to enhance the efficacy of immunotherapy. This review highlights the
Fenfen Zhan   +3 more
wiley   +1 more source

Crystal structure of Methanococcus jannaschii dihydroorotase with substrate bound

open access: yesActa Crystallographica Section F, Volume 82, Issue 1, Page 23-31, January 2026.
We present the 1.87 Å resolution structure of M. jannaschii dihydroorotase complexed with the substrate carbamoyl aspartate at room temperature. Contrary to expectations, a flexible loop which is important in catalysis and closes upon substrate binding in order to stabilize the substrate and transition state is observed in both the loop‐out and loop‐in
Jacqueline Vitali   +3 more
wiley   +1 more source

Folate Interaction With Genetic Risk for Neural Tube Defects Among Infants in Bangladesh

open access: yesBirth Defects Research, Volume 117, Issue 12, December 2025.
ABSTRACT Background Neural tube defects such as spina bifida (SB) are congenital anomalies associated with significant morbidity and mortality worldwide. Environmental factors, particularly folate, modify SB risk. Based on recurrence rates of SB within families, genetic risk also contributes to SB development.
Enrique Mondragon‐Estrada   +13 more
wiley   +1 more source

Exploration of Human Skin Phageome to Reveal Endolysins and Novel Antimicrobial Peptides for Therapeutic Applications

open access: yesMicrobiologyOpen, Volume 14, Issue 6, December 2025.
This study uncovers diverse endolysins and novel antimicrobial peptides from the human skin phageome, highlighting their potential to target antibiotic‐resistant pathogens and disrupt virulence mechanisms, paving the way for next‐generation skin therapeutics.
Jibon Kumar Paul   +6 more
wiley   +1 more source

Breaking barriers: pCF10 type 4 secretion system relies on a self-regulating muramidase to modulate the cell wall

open access: yesmBio
Conjugative type 4 secretion systems (T4SSs) are the main driver for the spread of antibiotic resistance genes and virulence factors in bacteria.
Wei-Sheng Sun   +4 more
doaj   +1 more source

Properties of rat liver N-acylethanolamine amidohydrolase.

open access: yesJournal of Biological Chemistry, 1985
Rat liver microsomes and mitochondria contain an amidohydrolase which catalyzes the hydrolysis of N-acylethanolamine to ethanolamine and fatty acid. The enzyme is active over a wide range of pH, does not require divalent cations, and is inhibited by sulfhydryl-reactive agents.
P C, Schmid   +2 more
openaire   +2 more sources

The Acylamide Amidohydrolase of Candida utilis: Purification and Properties [PDF]

open access: yesJournal of General Microbiology, 1969
SUMMARY: The amidohydrolase formed in the later stages of growth on glucose peptone medium by Candida utilis was purified 60-fold from cell-free extracts. The purified enzyme hydrolysed mono- and di-carboxylic acid amides, benzamide, nicotinamide, pyrazinamide and certain β-hydroxyl substituted fatty acid amides, was inactive on l-asparagine and l ...
openaire   +2 more sources

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