Results 61 to 70 of about 6,806 (259)
Environmental Microbiology Reports, Volume 18, Issue 1, February 2026.The Antarctic Dietzia and Pusillimonas isolates were tested for bioremediation applications. Genomic analyses revealed the potential to degrade complex organic compounds, potential virulence factors and resistance genes. Physiological assays showed a wide range of adaptation to abiotic factors and sensitivity to different groups of antibiotics ...
Tomasz Krucoń +4 more
wiley +1 more source
Characterization of the gene cluster involved in allantoate catabolism and its transcriptional regulation by the RpiR-type repressor HpxU in Klebsiella pneumoniae [PDF]
, 2013 Bacteria, fungi, and plants have metabolic pathways for the utilization of nitrogen present in purine bases. In Klebsiella pneumoniae, the genes responsible for the assimilation of purine ring nitrogen are distributed in three separated clusters.
Evangelina Campos +7 more
core +1 more source
Untersuchungen zum Ursprung der Substratspezifität von Enzymen der Amidohydrolase‐Superfamilie
Angewandte Chemie, Volume 138, Issue 4, 22 January 2026.Umfassende Analysen zweier Enzymklassen aus der Amidohydrolase‐Superfamilie (AHS) ergaben, dass die Katalyse über eine 1,4‐ bzw. 1,6‐nukleophile konjugierte Addition abläuft und diese Eigenschaft die Substratspezifität bestimmt. Obwohl alle Substrate und Produkte vollständig achiral sind, führt dieser mechanistische Unterschied zu einer invertierten ...
Lukas Drexler +3 more
wiley +1 more source
Improvement of root architecture under abiotic stress through control of auxin homeostasis in Arabidopsis and Brassica crops [PDF]
, 2015 Auxin plays an important role in many aspects of plant development including stress responses. Here we briefly summarize how auxin is involved in salt stress, drought (i.e.
Gruden, Kristina +4 more
core +2 more sources
Molecular aspects and comparative genomics of bacteriophage endolysins [PDF]
, 2013 Phages are recognized as the most abundant and diverse entities on the planet. Their diversity is predominantly determined by their dynamic adaptation capacities, when confronted with different selective pressures in an endless cycle of co-evolution with
Azeredo, Joana +7 more
core +1 more source
The use of asparaginase to reduce acrylamide levels in cooked food [PDF]
, 2016 Strategies proposed for reducing the formation of the suspected carcinogen acrylamide in cooked foods often rely on a reduction in the extent of the Maillard reaction, in which acrylamide is formed from the reaction between asparagine and reducing sugars.
Elmore, J. Stephen +2 more
core +1 more source
Decoding Urease Inhibition: A Comprehensive Review of Inhibitor Scaffolds
ChemMedChem, Volume 21, Issue 2, January 2026.Representative functional groups known for urease inhibition are reviewed within diverse scaffolds using structure–activity analyses to identify features associated with high inhibitory activity. Urease is a metalloenzyme produced by a wide range of organisms and plays a critical role in nitrogen microbial metabolism by catalyzing the hydrolysis of ...
Nuno Martinho, Natália Aniceto
wiley +1 more source
Using a nitrilase for the surface modification of acrylic fibres [PDF]
, 2007 The surface of an acrylic fibre was modified with a commercial nitrilase (EC 3.5.5.1). The effect of fibre solvents and polyols on nitrilase catalysis efficiency and stability was investigated.
Caparrós Vásquez, Cristina Maria +4 more
core +1 more source
Immunity, Inflammation and Disease, Volume 14, Issue 1, January 2026.The interplay between ferroptosis and the tumor immune microenvironment significantly influences the outcome of cancer immunotherapy. Inducing ferroptosis in tumor cells and immunosuppressive cells, while preventing ferroptosis in effector immune cells, emerges as a promising strategy to enhance the efficacy of immunotherapy. This review highlights the
Fenfen Zhan +3 more
wiley +1 more source
Crystal structure of Methanococcus jannaschii dihydroorotase with substrate bound
Acta Crystallographica Section F, Volume 82, Issue 1, Page 23-31, January 2026.We present the 1.87 Å resolution structure of M. jannaschii dihydroorotase complexed with the substrate carbamoyl aspartate at room temperature. Contrary to expectations, a flexible loop which is important in catalysis and closes upon substrate binding in order to stabilize the substrate and transition state is observed in both the loop‐out and loop‐in
Jacqueline Vitali +3 more
wiley +1 more source